Detailed information NTG0852895

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: V6T01_RS00315
• Genome accession: NZ_CP145856
• Coordinates: 51076..53607 (+)
• Length: 843 a.a.
• NCBI ID: WP_410541683.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain KSS1
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 46076..58607

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6T01_RS00290 (V6T01_00290)	-	46413..47261 (+)	849	WP_084915136.1	hypothetical protein	-
V6T01_RS00295 (V6T01_00295)	-	47301..47546 (+)	246	Protein_37	adenylosuccinate lyase	-
V6T01_RS00300 (V6T01_00300)	argS	48423..50114 (-)	1692	WP_002889584.1	arginine--tRNA ligase	-
V6T01_RS00305 (V6T01_00305)	argR	50269..50697 (+)	429	WP_171963598.1	arginine repressor	-
V6T01_RS00310 (V6T01_00310)	-	50697..51056 (+)	360	WP_410541268.1	YlbF family regulator	-
V6T01_RS00315 (V6T01_00315)	hexA	51076..53607 (+)	2532	WP_410541683.1	DNA mismatch repair protein MutS	Machinery gene
V6T01_RS00320 (V6T01_00320)	-	53641..54096 (-)	456	WP_060972120.1	DUF3021 domain-containing protein	-
V6T01_RS00325 (V6T01_00325)	-	54093..54530 (-)	438	WP_013989911.1	LytTR family DNA-binding domain-containing protein	-
V6T01_RS00330 (V6T01_00330)	-	54709..55014 (+)	306	WP_410541266.1	hypothetical protein	-
V6T01_RS00335 (V6T01_00335)	hexB	55066..57009 (+)	1944	WP_410541265.1	DNA mismatch repair endonuclease MutL	Machinery gene
V6T01_RS00340 (V6T01_00340)	-	57141..57362 (+)	222	WP_073690141.1	hypothetical protein	-
V6T01_RS00345 (V6T01_00345)	ruvA	57520..58110 (+)	591	WP_013989915.1	Holliday junction branch migration protein RuvA	Machinery gene

Sequence

Protein

• Length: 843 a.a.
• Molecular weight: 94745.73 Da
• Isoelectric Point: 4.6147

>NTDB_id=852895 V6T01_RS00315 WP_410541683.1 51076..53607(+) (hexA) [Streptococcus salivarius strain KSS1]
MQQYLDIKENYPDAFLLFRMGDFYELFYDDAVKAAQILEISLTSRNKNADNPIPMAGVPYHSAQAYIDVLVEMGYKVAIA
EQMEDPKQAVGVVKREVVQVITPGTVVDSSKPDNANNFLVAIDKVESRFGLAYMDVSTGEFFATELDDFSSVCSEIQNLK
AREVVVGYDLPEADEQVLVKQLNLLLSKETEVYDDVHLIDTSLTDLESSVAGKLLQYVHRTQMRELSHLQKAQHYEIKDY
LQMSYATKSSLDLLENARTGKKHGSLFWLLDETKTAMGMRLLRTWIDRPLVNQATITERQNIIQVFLDNFFERSDLTESL
KGVYDIERLASRVSFGKANPKDLIQLGHTLAQVPVIKAILESFNDEALSRLLQELDALPELESLIRSAIDPDAPATITEG
GIIRAGFDETLDKYRKVMSEGTSWIADIEAKEREASGITTLKIDYNRKDGYYFHVTNSNLSLVPDHFFRKATLKNSERFG
TAELAKIEGEMLEAREKSSTLEYDIFMRVREQVERYIDRLQYLAKAIATVDVLQSLAVVAETNHYVRPVFNDEHRIVIDQ
GRHAVVEKVMGVQEYIPNTITFDSQTNIQLITGPNMSGKSTYMRQLALSVVMAQMGSYVPADSIDLPVFDAIYTRIGAAD
DLISGQSTFMVEMMEANQAIKRATPNSLIIFDELGRGTATYDGMALAQSIIEFIHDKVGAKTMFATHYHELTALSNSLTH
LVNVHVATLEKDGEVTFLHKIVDGPADKSYGIHVAKIAGLPADLLERADTILTQLEGDTVTIQPQEKVSPQEKSATETHV
NEQISLFDDFTENPVLQELRDLDIYNMTPMQVMMAVADLKQKL

Nucleotide

• Length: 2532 bp

>NTDB_id=852895 V6T01_RS00315 WP_410541683.1 51076..53607(+) (hexA) [Streptococcus salivarius strain KSS1]
ATGCAGCAGTATTTGGATATCAAGGAAAATTATCCAGATGCTTTTTTGCTGTTTCGGATGGGGGATTTTTACGAATTATT
TTACGATGATGCCGTTAAGGCTGCTCAAATTTTGGAAATTAGCCTAACCAGTCGTAATAAGAACGCAGATAATCCCATTC
CTATGGCAGGTGTTCCTTATCATTCGGCTCAAGCCTATATTGATGTCTTGGTTGAGATGGGCTACAAAGTAGCCATTGCT
GAGCAGATGGAGGACCCTAAACAGGCTGTTGGCGTGGTTAAGCGTGAGGTAGTTCAGGTTATCACGCCAGGGACAGTGGT
TGACAGCTCTAAACCTGATAATGCCAACAATTTCTTAGTAGCCATTGACAAGGTTGAAAGTCGATTCGGCCTGGCCTATA
TGGATGTATCAACGGGTGAATTTTTTGCGACAGAGTTGGATGATTTTAGTTCAGTTTGCAGTGAAATTCAGAATCTTAAG
GCACGTGAAGTAGTCGTTGGGTATGATTTACCTGAAGCTGATGAACAAGTTTTGGTCAAGCAACTCAACCTGCTTCTCTC
CAAGGAAACAGAGGTTTACGATGATGTCCACTTGATTGACACTAGTTTGACAGATTTGGAAAGCAGTGTGGCGGGTAAAC
TTCTCCAGTATGTTCATCGTACTCAGATGCGAGAGCTCAGTCATTTACAAAAGGCTCAGCACTATGAGATTAAAGATTAC
TTGCAGATGTCCTATGCGACCAAGTCAAGTTTGGATTTACTGGAAAATGCTAGGACGGGCAAGAAACACGGATCTCTTTT
CTGGCTCTTGGATGAAACCAAGACAGCTATGGGAATGCGTCTCTTGCGAACTTGGATTGATCGTCCTTTAGTGAATCAAG
CCACTATCACCGAGCGTCAGAATATCATCCAAGTTTTCTTGGACAATTTCTTTGAGCGTAGTGACTTGACTGAGAGTCTA
AAAGGTGTTTACGATATTGAGCGCCTGGCCAGTCGTGTTTCCTTTGGCAAGGCTAATCCAAAAGATTTGATTCAGCTAGG
TCATACTTTGGCTCAAGTACCGGTCATTAAGGCGATTTTGGAGTCTTTTAATGATGAGGCCTTGTCACGTCTTTTACAAG
AGTTAGATGCTCTGCCAGAATTAGAGAGTTTGATTCGGTCGGCTATTGATCCTGATGCCCCTGCAACCATTACAGAAGGT
GGCATTATCCGTGCTGGTTTTGATGAGACCTTGGACAAGTATCGCAAGGTGATGAGTGAGGGAACCTCATGGATCGCAGA
TATCGAAGCCAAGGAACGTGAAGCGTCTGGTATTACAACACTAAAGATTGATTATAACCGTAAAGATGGTTATTACTTCC
ATGTGACCAACTCTAACCTTAGCTTGGTTCCTGACCATTTCTTCCGCAAGGCAACCCTGAAAAATTCAGAGCGCTTTGGA
ACTGCTGAGTTGGCTAAGATAGAAGGTGAAATGCTTGAGGCGCGTGAAAAATCATCAACGCTGGAATATGATATTTTCAT
GCGTGTCCGTGAGCAGGTTGAACGCTATATTGACCGTTTGCAATATTTGGCTAAGGCTATTGCGACAGTCGATGTGCTTC
AGAGTCTAGCTGTTGTAGCAGAGACTAATCATTATGTTCGTCCTGTGTTCAATGATGAGCATCGTATTGTTATTGATCAA
GGCCGTCATGCAGTGGTTGAGAAGGTTATGGGCGTTCAAGAATACATTCCAAACACCATTACCTTTGACAGTCAGACCAA
TATTCAGCTCATCACAGGACCAAATATGAGTGGTAAATCCACCTATATGCGTCAGTTAGCCTTGTCAGTAGTTATGGCTC
AGATGGGGTCTTACGTGCCAGCAGATAGTATTGACTTGCCAGTTTTTGATGCTATCTATACACGTATTGGTGCTGCAGAT
GATCTGATTTCAGGTCAGTCGACCTTCATGGTTGAGATGATGGAGGCTAATCAGGCCATTAAGCGGGCGACACCTAATTC
CTTGATTATTTTTGATGAGTTGGGACGTGGGACAGCTACCTATGATGGTATGGCCTTAGCTCAGTCTATTATTGAGTTTA
TTCATGACAAGGTGGGGGCTAAGACCATGTTTGCTACCCATTATCATGAGTTGACAGCCCTGTCAAACAGTTTGACACAC
CTTGTAAACGTTCATGTGGCGACACTTGAAAAGGACGGTGAAGTGACTTTCCTTCACAAGATTGTCGATGGACCAGCCGA
CAAATCTTATGGTATTCATGTAGCTAAGATTGCAGGTTTACCAGCAGATTTACTGGAACGTGCTGACACCATCTTGACAC
AACTTGAGGGCGATACAGTTACCATCCAACCTCAGGAAAAGGTATCGCCTCAAGAGAAATCTGCCACTGAAACGCATGTC
AACGAGCAAATCTCTCTCTTTGATGATTTTACTGAAAATCCAGTTCTTCAAGAGTTGCGTGATTTAGATATTTACAACAT
GACACCTATGCAGGTCATGATGGCTGTAGCAGATTTAAAACAGAAACTATAA

Domains

Predicted by InterProScan.

• MutS domain III (MutS_III) (247-537)

• MutS domain I (MutS_I) (1-109)

• MutS domain II (MutS_II) (117-230)

• MutS domain V (MutS_V) (590-776)

• MutS family domain IV (MutS_IV) (406-496)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	74.259	100	0.743
mutS	Pseudomonas stutzeri strain ATCC 17587	36.311	100	0.371