Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   V6T01_RS00335 Genome accession   NZ_CP145856
Coordinates   55066..57009 (+) Length   647 a.a.
NCBI ID   WP_410541265.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS1     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 50066..62009
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6T01_RS00305 (V6T01_00305) argR 50269..50697 (+) 429 WP_171963598.1 arginine repressor -
  V6T01_RS00310 (V6T01_00310) - 50697..51056 (+) 360 WP_410541268.1 YlbF family regulator -
  V6T01_RS00315 (V6T01_00315) hexA 51076..53607 (+) 2532 WP_410541683.1 DNA mismatch repair protein MutS Machinery gene
  V6T01_RS00320 (V6T01_00320) - 53641..54096 (-) 456 WP_060972120.1 DUF3021 domain-containing protein -
  V6T01_RS00325 (V6T01_00325) - 54093..54530 (-) 438 WP_013989911.1 LytTR family DNA-binding domain-containing protein -
  V6T01_RS00330 (V6T01_00330) - 54709..55014 (+) 306 WP_410541266.1 hypothetical protein -
  V6T01_RS00335 (V6T01_00335) hexB 55066..57009 (+) 1944 WP_410541265.1 DNA mismatch repair endonuclease MutL Machinery gene
  V6T01_RS00340 (V6T01_00340) - 57141..57362 (+) 222 WP_073690141.1 hypothetical protein -
  V6T01_RS00345 (V6T01_00345) ruvA 57520..58110 (+) 591 WP_013989915.1 Holliday junction branch migration protein RuvA Machinery gene
  V6T01_RS00350 (V6T01_00350) - 58119..58673 (+) 555 WP_073951167.1 DNA-3-methyladenine glycosylase I -
  V6T01_RS00355 (V6T01_00355) cinA 58770..60035 (+) 1266 WP_410533800.1 competence/damage-inducible protein A Machinery gene
  V6T01_RS00360 (V6T01_00360) recA 60076..61215 (+) 1140 WP_002889600.1 recombinase RecA Machinery gene
  V6T01_RS00365 (V6T01_00365) spx 61383..61781 (+) 399 WP_002886328.1 transcriptional regulator Spx -

Sequence

Protein


Download         Length: 647 a.a.        Molecular weight: 72534.62 Da        Isoelectric Point: 5.2831

>NTDB_id=852896 V6T01_RS00335 WP_410541265.1 55066..57009(+) (hexB) [Streptococcus salivarius strain KSS1]
MPKIIELPEVLANQIAAGEVVERPASVVKELVENAIDAGSTQITIEVEESGLSKIQITDNGEGMAQADVAMSLRRHATSK
IKNQGDLFRIRTLGFRGEALPSIASISHLTIVTAADGEAYGTKLVAKGGEIESQDPISTPVGTKITVENLFYNTPARLKY
MKSLQAELAHIVDVVNRLSLAHPEVAFTLLNDGRQLTQTSGTGDLRQAIAGIYGLTTAKKMVEISNSDLDFEVSGYVSLP
ELTRANRNYITILINGRYIKNFLLNRAIFDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKEKELMALISS
AIAQSLREQDLIPDALENLAKSSTRGATKPVQTSLPLKQTNLYYDSSRNDFFVKPETVQEDIKPLVSESESSVSSVENKP
QPTVKQAKRLADDSDSEHEKLDYKNKSKMKRMLENLDNEETSTFPELEFFGQMHGTYLFAQGQGGLYIIDQHAAQERVKY
EYYREKIGEVDSSLQQLLVPYLFEFSGSDYISLQEKMALLNQVGIYLEPYGNNTFILREHPIWMKEEEIESAVYEMCDML
LLTNEVSVKTYRAELAIMMSCKRSIKANHALDDYSARDLLVQLAQCKNPYNCPHGRPVLVNFTKSDMEKMFRRIQENHTS
LRDLGKY

Nucleotide


Download         Length: 1944 bp        

>NTDB_id=852896 V6T01_RS00335 WP_410541265.1 55066..57009(+) (hexB) [Streptococcus salivarius strain KSS1]
ATGCCAAAAATCATCGAATTGCCTGAAGTTCTAGCCAATCAGATTGCTGCTGGAGAGGTCGTAGAGCGACCAGCTAGTGT
AGTTAAAGAGCTGGTGGAAAATGCTATTGATGCAGGCAGCACCCAGATTACTATTGAAGTTGAAGAATCAGGCCTCTCAA
AAATTCAAATTACAGACAATGGCGAAGGAATGGCTCAAGCTGACGTGGCTATGAGTTTGCGCCGTCATGCAACAAGTAAA
ATCAAAAATCAAGGAGACCTCTTTCGTATTCGAACTCTTGGTTTTCGAGGTGAGGCCCTGCCATCAATAGCTTCTATCAG
TCATCTTACCATTGTGACGGCGGCTGATGGAGAAGCCTATGGGACTAAACTGGTTGCTAAAGGTGGAGAAATTGAGAGTC
AGGATCCTATTTCAACACCAGTTGGAACAAAGATTACCGTTGAAAACTTATTTTATAATACCCCTGCTCGTCTCAAGTAT
ATGAAGAGTTTACAGGCCGAGTTGGCTCATATTGTCGATGTTGTCAATCGTCTGAGTCTAGCTCATCCCGAAGTTGCCTT
CACCTTGCTTAATGACGGCCGTCAGTTGACACAGACCTCAGGTACTGGAGACCTCCGTCAAGCTATTGCCGGGATTTATG
GTTTGACAACGGCTAAAAAAATGGTGGAAATTTCAAATTCTGACCTTGATTTTGAAGTTTCTGGCTATGTTAGTCTCCCT
GAGTTGACCCGTGCGAATCGTAACTACATCACGATTCTCATTAACGGACGTTATATAAAAAACTTCCTACTTAACCGTGC
TATTTTTGATGGTTATGGTTCTAAACTCATGGTAGGGCGCTTCCCTATTGCGGTTATTGATATTCAAATTGATCCCTATT
TGGCTGATGTCAATGTTCACCCAACAAAGCAGGAAGTACGTATCTCTAAAGAAAAGGAGCTTATGGCCCTCATCAGCTCT
GCCATTGCTCAAAGCCTTAGAGAGCAGGATTTGATTCCTGATGCCCTTGAAAATCTAGCCAAGTCTAGTACTAGAGGTGC
AACTAAGCCGGTTCAAACCAGTCTTCCACTCAAACAAACCAATCTTTACTATGATAGCAGTCGTAATGATTTCTTTGTCA
AACCAGAGACAGTTCAAGAGGATATCAAACCTCTTGTATCAGAGTCAGAGTCTTCAGTTTCATCGGTAGAAAACAAACCG
CAACCTACTGTTAAACAGGCAAAACGTTTAGCAGATGATAGTGATAGTGAACACGAAAAACTTGATTATAAAAACAAGTC
GAAAATGAAGCGCATGCTTGAAAATCTGGACAATGAGGAAACATCAACCTTCCCTGAGTTGGAGTTTTTTGGTCAAATGC
ATGGAACCTATCTCTTTGCTCAAGGACAAGGTGGACTTTACATCATTGACCAGCATGCTGCCCAAGAACGTGTCAAGTAT
GAGTACTATCGCGAAAAGATTGGTGAGGTTGACAGTAGCTTACAACAGCTTTTGGTTCCCTATCTCTTTGAATTTTCAGG
TTCGGATTACATTAGTTTACAAGAAAAAATGGCTCTTCTTAACCAGGTTGGTATCTATTTAGAGCCTTATGGGAATAACA
CCTTCATTCTTCGTGAACATCCTATCTGGATGAAGGAAGAAGAGATTGAATCTGCAGTCTATGAGATGTGCGACATGCTT
CTTTTGACGAATGAAGTGTCTGTTAAGACCTACCGTGCTGAGTTAGCCATCATGATGAGTTGTAAACGTTCAATCAAGGC
CAATCATGCTCTTGATGATTACTCTGCGCGTGACCTCCTAGTGCAGCTTGCACAGTGTAAAAACCCCTACAATTGCCCTC
ACGGACGTCCTGTACTTGTCAACTTTACAAAGTCTGATATGGAAAAAATGTTCCGTCGAATTCAAGAAAATCATACTAGT
CTACGTGACCTAGGGAAGTATTAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)

MutL C terminal dimerisation domain (MutL_C)

(448-591)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

70

100

0.703