Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   QYE83_RS04030 Genome accession   NZ_CP129372
Coordinates   879108..879824 (-) Length   238 a.a.
NCBI ID   WP_001829999.1    Uniprot ID   C0LF82
Organism   Staphylococcus epidermidis strain CCSH-141     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 874108..884824
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QYE83_RS04015 - 875389..876342 (+) 954 WP_002447518.1 LacI family DNA-binding transcriptional regulator -
  QYE83_RS04020 - 876602..878074 (+) 1473 WP_150871544.1 sucrose-6-phosphate hydrolase -
  QYE83_RS04025 - 878081..879040 (+) 960 WP_060546487.1 carbohydrate kinase -
  QYE83_RS04030 agrA 879108..879824 (-) 717 WP_001829999.1 quorum-sensing response regulator AgrA Regulator
  QYE83_RS04035 agrC 879841..881130 (-) 1290 WP_150871541.1 quorum-sensing sensor histidine kinase AgrC -
  QYE83_RS04040 agrD 881155..881295 (-) 141 WP_002447513.1 cyclic lactone autoinducer peptide AgrD -
  QYE83_RS04045 - 881301..881864 (-) 564 WP_002457915.1 accessory gene regulator AgrB -
  QYE83_RS04050 hld 882181..882258 (+) 78 WP_002494082.1 delta-hemolysin -
  QYE83_RS04055 - 882638..883423 (-) 786 WP_002457916.1 carbon-nitrogen family hydrolase -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27936.97 Da        Isoelectric Point: 5.6250

>NTDB_id=852882 QYE83_RS04030 WP_001829999.1 879108..879824(-) (agrA) [Staphylococcus epidermidis strain CCSH-141]
MKIFVCEDDQRQREHMVSIIKNYIMIEEKPMELALATNDPYEVLEQSKELNDIGCYFLDIQLEADMNGIKLASEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPSELKMRIIDCLETAHTRLKLLSKESNVDTIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELAQLDERFFRCHNSFVINRHNIESIDSKERIVYFKNGENCFASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=852882 QYE83_RS04030 WP_001829999.1 879108..879824(-) (agrA) [Staphylococcus epidermidis strain CCSH-141]
ATGAAAATTTTTGTTTGTGAAGATGACCAAAGACAAAGAGAACATATGGTATCAATCATTAAAAACTACATAATGATTGA
AGAAAAGCCAATGGAGTTAGCTTTAGCAACAAATGATCCTTATGAGGTCTTAGAGCAATCAAAAGAACTTAATGACATTG
GTTGTTACTTCCTTGATATTCAATTAGAAGCTGATATGAACGGTATTAAATTAGCCAGTGAAATTCGTAAACATGATCCT
GTTGGTAATATTATATTTGTAACCAGTCACAGTGAACTGACTTATTTGACGTTTGTTTATAAAGTGGCTGCTATGGATTT
TATTTTTAAGGATGATCCATCTGAATTAAAAATGAGAATCATAGATTGTCTTGAAACAGCACATACACGACTCAAATTAT
TATCTAAAGAAAGTAATGTAGATACGATTGAGTTAAAACGTGGAAGTAATTCAGTATACGTTCAATATGATGATATTATG
TTTTTTGAATCATCTACGAAATCTCATAGACTCATCGCACATCTTGATAATCGACAAATTGAATTTTATGGAAATTTAAA
GGAATTAGCACAGCTTGATGAACGTTTTTTTAGATGTCATAACAGTTTTGTAATAAACAGGCATAATATTGAATCTATTG
ATTCAAAAGAACGTATTGTTTACTTTAAGAATGGCGAAAATTGTTTCGCTTCAGTACGTAATGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB C0LF82

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

87.815

100

0.878
  comE/comE2 Streptococcus gordonii strain NCTC7865

35.178

100

0.374
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

35.178

100

0.374