Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   QUE31_RS18670 Genome accession   NZ_AP027254
Coordinates   3726249..3726881 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain JNE120442     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3721249..3731881
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QUE31_RS18645 (JNE120442_35470) yheS 3721418..3723331 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  QUE31_RS18650 (JNE120442_35480) yheT 3723331..3724353 (+) 1023 WP_042103628.1 hydrolase -
  QUE31_RS18655 (JNE120442_35490) yheU 3724347..3724565 (+) 219 WP_000907085.1 YheU family protein -
  QUE31_RS18660 (JNE120442_35500) prkB 3724619..3725488 (+) 870 WP_001274680.1 phosphoribulokinase -
  QUE31_RS18665 (JNE120442_35510) yhfA 3725543..3725947 (-) 405 WP_001148908.1 OsmC family protein -
  QUE31_RS18670 (JNE120442_35520) crp 3726249..3726881 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  QUE31_RS18675 (JNE120442_35530) yhfK 3726932..3729022 (+) 2091 WP_001571992.1 YccS/YhfK family putative transporter -
  QUE31_RS18680 (JNE120442_35540) argD 3729089..3730309 (-) 1221 WP_001525813.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  QUE31_RS18685 (JNE120442_35550) pabA 3730395..3730958 (-) 564 WP_042103625.1 aminodeoxychorismate synthase component 2 -
  QUE31_RS18690 (JNE120442_35560) fic 3730990..3731592 (-) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  QUE31_RS18695 (JNE120442_35570) yhfG 3731582..3731749 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=85182 QUE31_RS18670 WP_000242755.1 3726249..3726881(+) (crp) [Escherichia coli strain JNE120442]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=85182 QUE31_RS18670 WP_000242755.1 3726249..3726881(+) (crp) [Escherichia coli strain JNE120442]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467