Detailed information NTG0849084

Bioinformatically predicted

Overview

• Name: pilU
• Type: Machinery gene
• Locus tag: V5F93_RS09925
• Genome accession: NZ_CP145035
• Coordinates: 1891172..1892398 (-)
• Length: 408 a.a.
• NCBI ID: WP_047923710.1
• Uniprot ID: -
• Organism: Neisseria gonorrhoeae strain WHO_P_2024
• Function: mediate the depolymerization of the type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1886172..1897398

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V5F93_RS09915 (V5F93_09935)	-	1888141..1888425 (+)	285	WP_003692093.1	GIY-YIG nuclease family protein	-
V5F93_RS09920 (V5F93_09940)	yccS	1888905..1891055 (-)	2151	WP_003697785.1	YccS family putative transporter	-
V5F93_RS09925 (V5F93_09945)	pilU	1891172..1892398 (-)	1227	WP_047923710.1	PilT/PilU family type 4a pilus ATPase	Machinery gene
V5F93_RS09930 (V5F93_09950)	pilT	1892562..1893605 (-)	1044	WP_003690200.1	type IV pilus twitching motility protein PilT	Machinery gene
V5F93_RS09935 (V5F93_09955)	-	1893725..1894411 (+)	687	WP_003690201.1	YggS family pyridoxal phosphate-dependent enzyme	-
V5F93_RS09940 (V5F93_09960)	-	1894411..1894818 (+)	408	WP_003701818.1	hypothetical protein	-
V5F93_RS09945 (V5F93_09965)	proC	1894867..1895658 (+)	792	WP_003692105.1	pyrroline-5-carboxylate reductase	-
V5F93_RS09950 (V5F93_09970)	dksA	1895807..1896223 (+)	417	WP_003692108.1	RNA polymerase-binding protein DksA	-

Sequence

Protein

• Length: 408 a.a.
• Molecular weight: 45611.20 Da
• Isoelectric Point: 6.9230

>NTDB_id=849084 V5F93_RS09925 WP_047923710.1 1891172..1892398(-) (pilU) [Neisseria gonorrhoeae strain WHO_P_2024]
MNTDNLHDILDETVQVYSQKNKAESETPAEIGAHFHPLLDRLCETAEAQNASDILISKGFPPSLKINSALTPQPQKALTG
EETAAIAASTMNAEQSEIFRRDGEINYSVQSRSGTRYRANAYYSQGSAGLVLRRINHVIPQMRELGLPEKLKDLAVAPRG
LLIIVGPTGSGKSTTMATMLEHRNKTLPGHIVTIEDPIEFIYKPRRCIFTQREIGVDTINWQTAVQNAMRQSPDVVCIGE
VRSRESMEYAMQLAQTGHLCIFTLHANTAPQSLERILNFYPKEQHNQILIDIALNLTGIICQRLALKKDKTGRTAVVDLL
INTPAIQDFILKGDLMNISKIMETAKTDGMQTMDQNLFELYRHGIISYEEALRQSVSANNLRLHIQLHKEGKTPELLYDR
VNGLNLIS

Nucleotide

• Length: 1227 bp

>NTDB_id=849084 V5F93_RS09925 WP_047923710.1 1891172..1892398(-) (pilU) [Neisseria gonorrhoeae strain WHO_P_2024]
ATGAATACCGATAACCTGCACGACATCTTGGACGAAACGGTTCAAGTGTATTCTCAAAAAAACAAAGCCGAATCCGAAAC
CCCGGCCGAAATCGGCGCACACTTCCACCCGCTGCTCGACCGCCTGTGCGAAACCGCAGAAGCACAAAACGCGTCCGACA
TCCTTATCAGCAAAGGATTCCCGCCCTCGTTGAAAATCAACAGCGCATTAACCCCGCAGCCGCAAAAGGCTCTGACGGGC
GAGGAAACCGCCGCCATCGCCGCATCGACGATGAACGCCGAACAATCGGAAATATTCCGGCGCGACGGCGAAATCAACTA
CTCCGTCCAATCGCGCAGCGGCACGCGCTACCGCGCCAACGCCTACTACAGCCAAGGCAGCGCAGGTTTGGTTTTGCGGC
GCATCAACCACGTCATCCCGCAAATGCGGGAATTGGGCTTGCCCGAAAAACTCAAAGACCTCGCCGTCGCACCGCGCGGG
CTGCTGATTATCGTCGGGCCTACCGGTTCGGGCAAATCCACCACGATGGCGACTATGCTCGAACACCGCAACAAAACCCT
GCCCGGCCATATCGTTACCATCGAAGACCCGATTGAGTTTATCTACAAACCGCGCCGCTGCATCTTTACCCAGCGCGAAA
TCGGCGTCGACACCATAAACTGGCAGACGGCGGTACAAAACGCTATGCGCCAATCCCCAGACGTGGTCTGTATCGGCGAA
GTCCGCAGCAGGGAAAGTATGGAATACGCGATGCAGCTCGCCCAAACCGGCCACCTGTGCATTTTTACGCTCCACGCCAA
CACCGCGCCGCAGTCGCTCGAACGCATACTCAACTTCTACCCCAAAGAACAGCACAACCAAATACTGATTGACATCGCCC
TCAATCTGACCGGCATCATCTGCCAACGCCTCGCCCTCAAAAAAGACAAAACGGGCAGGACGGCGGTTGTCGACTTGCTC
ATCAACACGCCCGCCATCCAAGACTTCATCCTGAAGGGCGACCTGATGAACATCAGTAAAATCATGGAAACCGCCAAAAC
CGACGGAATGCAGACGATGGACCAAAACCTTTTCGAACTGTACCGTCACGGCATCATCAGTTACGAAGAAGCCCTGCGCC
AGTCCGTTTCCGCCAACAACCTGCGATTGCACATCCAACTGCACAAAGAAGGCAAAACGCCCGAACTCCTTTACGACAGG
GTCAACGGTCTCAACCTCATTTCCTGA

Domains

Predicted by InterProScan.

• Type II/IV secretion system protein (T2SSE) (49-305)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilU	Acinetobacter baylyi ADP1	44.875	88.48	0.397
pilU	Pseudomonas stutzeri DSM 10701	45.225	87.255	0.395
pilU	Vibrio cholerae strain A1552	47.024	82.353	0.387