Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   V5G19_RS02950 Genome accession   NZ_CP145028
Coordinates   558734..560761 (+) Length   675 a.a.
NCBI ID   WP_003691336.1    Uniprot ID   B4RMI9
Organism   Neisseria gonorrhoeae strain WHO_R_2024     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 553734..565761
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V5G19_RS02935 (V5G19_02940) - 554119..554679 (-) 561 WP_003691340.1 CreA family protein -
  V5G19_RS02940 (V5G19_02945) - 555006..556802 (+) 1797 WP_003691339.1 peptidoglycan DD-metalloendopeptidase family protein -
  V5G19_RS02945 (V5G19_02950) - 556929..558404 (+) 1476 WP_003691337.1 S41 family peptidase -
  V5G19_RS02950 (V5G19_02960) uvrB 558734..560761 (+) 2028 WP_003691336.1 excinuclease ABC subunit UvrB Machinery gene
  V5G19_RS02955 (V5G19_02965) cah 560939..561697 (-) 759 WP_003688976.1 carbonic anhydrase -
  V5G19_RS02960 (V5G19_02970) - 562106..562453 (-) 348 WP_010357745.1 hypothetical protein -
  V5G19_RS02965 (V5G19_02975) trmB 562777..563493 (-) 717 WP_003691335.1 tRNA (guanosine(46)-N7)-methyltransferase TrmB -
  V5G19_RS02970 (V5G19_02980) - 563615..565019 (-) 1405 Protein_580 tetratricopeptide repeat protein -

Sequence

Protein


Download         Length: 675 a.a.        Molecular weight: 77015.52 Da        Isoelectric Point: 5.0489

>NTDB_id=848903 V5G19_RS02950 WP_003691336.1 558734..560761(+) (uvrB) [Neisseria gonorrhoeae strain WHO_R_2024]
MEVIRYPNSPFKLHQPFPPAGDQPTAIAGLLEGLSDGLAYQTLLGVTGSGKTYTMANVIAQSGRPAIIMAHNKTLAAQLY
AEMREFFPENAVEYFVSYYDYYQPEAYVPSRDLFIEKDSAINEHIEQMRLSATKNLMTRDDVIIVATVSAIYGIGDPTEY
QQMVLSVKEGDTIEQRDIIATLVSMQYERGDLDFKRGSFRVRGDVIDVYPAESSENALRISLFDDEIDRLDMFDPLSGSL
HQRVGRYTVFPSSHYVTPRDTVLRACESIKEELRERIEFFAREQRPVEQQRIEQRTRFDLEMLYEMGFCKGIENYSRHFS
GKKEGEPPPTLMDYLPDNAIMFIDESHVTVTQIGGMYKGDALRKQNLVDYGFRLPSARDNRPLKFHEFEKVMPQTVFVSA
TPAKYEEEHAGQVVEQVVRPTGLVDPQIIIRPVATQVDDLMSEINDRIQKGERVLVTTLTKRMAEQLTDYYSELGIKVRY
LHSDIDTVERVEIIRDLRLGLFDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSHRSLIQTIGRAARNVNGVAILYAD
KITDSMKAAVDETERRREKQIKFNEEHGIVPQQIKKQVKDIIDGVYHEEDSGKGRRQGKNKVKVGEIHNEEDAIKEIAKL
EKAMQQAARDLQFEEAAVLRDRIRNIKENLLFGAE

Nucleotide


Download         Length: 2028 bp        

>NTDB_id=848903 V5G19_RS02950 WP_003691336.1 558734..560761(+) (uvrB) [Neisseria gonorrhoeae strain WHO_R_2024]
ATGGAAGTCATCCGATACCCAAATTCCCCCTTCAAACTCCACCAACCCTTCCCGCCCGCAGGCGACCAGCCCACCGCCAT
TGCGGGCCTGCTCGAAGGGCTTTCAGACGGCCTTGCCTACCAAACCCTGCTCGGCGTAACCGGTTCGGGCAAAACCTACA
CGATGGCGAACGTCATCGCGCAAAGCGGCAGACCCGCCATCATTATGGCGCACAACAAAACCCTTGCCGCCCAGCTTTAT
GCCGAAATGCGCGAGTTTTTCCCCGAAAACGCAGTGGAATATTTCGTGTCGTATTACGACTATTACCAGCCCGAAGCCTA
TGTGCCCAGCCGCGATTTGTTCATCGAAAAAGACAGCGCGATCAACGAACACATCGAGCAGATGCGCCTTTCCGCCACCA
AAAACCTGATGACGCGCGACGACGTGATTATCGTCGCCACCGTGTCCGCCATTTACGGTATCGGCGACCCGACCGAGTAT
CAACAAATGGTGCTGTCCGTAAAAGAAGGCGACACCATCGAGCAGCGCGACATCATCGCCACGCTCGTTTCCATGCAGTA
CGAACGCGGCGATTTGGACTTCAAACGCGGCAGCTTCCGCGTGCGCGGCGACGTGATTGACGTGTACCCCGCCGAAAGCT
CCGAAAACGCCTTGCGTATCAGCCTGTTTGATGACGAAATCGACCGCCTCGATATGTTCGACCCGCTTTCAGGCAGCCTG
CACCAGCGTGTCGGACGCTACACCGTCTTCCCGTCCAGCCACTACGTTACCCCGCGCGACACCGTATTGCGCGCCTGCGA
ATCCATCAAAGAAGAATTGCGCGAACGCATCGAATTTTTCGCTCGCGAACAACGCCCCGTCGAGCAACAACGCATCGAAC
AGCGCACCCGTTTCGACCTCGAAATGCTCTACGAAATGGGCTTCTGCAAAGGCATTGAAAACTACTCCCGCCACTTCTCC
GGTAAAAAAGAAGGCGAACCGCCGCCCACGCTGATGGACTACCTGCCCGACAACGCCATCATGTTCATCGACGAAAGCCA
CGTTACCGTTACCCAAATCGGCGGCATGTACAAAGGCGACGCATTGCGCAAGCAAAACCTCGTGGACTACGGCTTCCGCC
TGCCTTCCGCCCGCGACAACCGCCCGCTCAAATTCCACGAATTTGAAAAAGTCATGCCGCAAACCGTCTTCGTTTCCGCC
ACCCCCGCGAAATACGAAGAAGAACACGCCGGACAAGTCGTCGAACAAGTCGTCCGCCCCACAGGGCTGGTCGACCCCCA
AATCATCATCCGCCCCGTCGCCACCCAAGTCGACGATTTAATGAGCGAAATCAACGACCGTATTCAAAAAGGCGAACGTG
TGCTCGTTACCACCCTTACCAAACGCATGGCGGAGCAACTCACCGACTATTACAGCGAACTCGGCATCAAAGTGCGCTAC
CTGCACAGCGACATCGACACCGTCGAACGCGTTGAAATCATTAGAGATTTGCGGCTCGGCCTGTTTGACGTACTCGTTGG
CATCAACCTGTTGCGCGAAGGCCTCGACATCCCCGAAGTCTCCCTCGTCGCCATCCTCGATGCCGACAAAGAAGGCTTCC
TGCGCTCCCACCGCAGCCTGATTCAAACCATAGGCCGCGCCGCGCGCAACGTGAACGGCGTCGCCATCCTGTACGCCGAC
AAAATTACCGACTCCATGAAAGCCGCCGTCGACGAAACCGAACGCCGCCGCGAAAAACAGATTAAATTCAACGAAGAACA
CGGTATCGTGCCGCAGCAGATTAAAAAACAGGTCAAAGACATCATCGACGGCGTGTACCACGAAGAAGACAGTGGCAAAG
GCCGTAGACAAGGCAAAAACAAGGTCAAAGTCGGCGAAATCCACAACGAAGAAGACGCGATTAAAGAAATCGCCAAACTG
GAAAAAGCCATGCAGCAGGCGGCTAGGGATTTACAGTTTGAAGAAGCTGCTGTGTTGAGGGATAGGATTAGGAATATTAA
AGAGAATTTGTTGTTTGGGGCGGAGTGA

Domains

Predicted by InterProScan.

Ultra-violet resistance protein B (UvrB)

(557-598)

Helicase conserved C-terminal domain (Helicase_C)

(444-549)

UvrB interaction domain (UvrB_inter)

(165-255)

Type III restriction enzyme, res subunit (ResIII)

(23-144)

UvrB/uvrC motif (UVR)

(635-668)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B4RMI9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae TIGR4

55.053

98.222

0.541
  uvrB Streptococcus pneumoniae R6

55.053

98.222

0.541
  uvrB Streptococcus pneumoniae D39

55.053

98.222

0.541