Detailed information NTG0848872

Bioinformatically predicted

Overview

• Name: pilU
• Type: Machinery gene
• Locus tag: V5G02_RS09880
• Genome accession: NZ_CP145026
• Coordinates: 1889531..1890757 (-)
• Length: 408 a.a.
• NCBI ID: WP_047923710.1
• Uniprot ID: -
• Organism: Neisseria gonorrhoeae strain WHO_S2_2024
• Function: mediate the depolymerization of the type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1884531..1895757

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V5G02_RS09870 (V5G02_09885)	-	1886496..1886780 (+)	285	WP_003692093.1	GIY-YIG nuclease family protein	-
V5G02_RS09875 (V5G02_09890)	yccS	1887264..1889414 (-)	2151	WP_003697785.1	YccS family putative transporter	-
V5G02_RS09880 (V5G02_09895)	pilU	1889531..1890757 (-)	1227	WP_047923710.1	PilT/PilU family type 4a pilus ATPase	Machinery gene
V5G02_RS09885 (V5G02_09900)	pilT	1890921..1891964 (-)	1044	WP_003690200.1	type IV pilus twitching motility protein PilT	Machinery gene
V5G02_RS09890 (V5G02_09905)	-	1892084..1892770 (+)	687	WP_003690201.1	YggS family pyridoxal phosphate-dependent enzyme	-
V5G02_RS09895 (V5G02_09910)	-	1892770..1893177 (+)	408	WP_003701818.1	hypothetical protein	-
V5G02_RS09900 (V5G02_09915)	proC	1893226..1894017 (+)	792	WP_003692105.1	pyrroline-5-carboxylate reductase	-
V5G02_RS09905 (V5G02_09920)	dksA	1894166..1894582 (+)	417	WP_003692108.1	RNA polymerase-binding protein DksA	-
V5G02_RS09910 (V5G02_09925)	-	1894597..1894725 (+)	129	WP_256204576.1	hypothetical protein	-

Sequence

Protein

• Length: 408 a.a.
• Molecular weight: 45611.20 Da
• Isoelectric Point: 6.9230

>NTDB_id=848872 V5G02_RS09880 WP_047923710.1 1889531..1890757(-) (pilU) [Neisseria gonorrhoeae strain WHO_S2_2024]
MNTDNLHDILDETVQVYSQKNKAESETPAEIGAHFHPLLDRLCETAEAQNASDILISKGFPPSLKINSALTPQPQKALTG
EETAAIAASTMNAEQSEIFRRDGEINYSVQSRSGTRYRANAYYSQGSAGLVLRRINHVIPQMRELGLPEKLKDLAVAPRG
LLIIVGPTGSGKSTTMATMLEHRNKTLPGHIVTIEDPIEFIYKPRRCIFTQREIGVDTINWQTAVQNAMRQSPDVVCIGE
VRSRESMEYAMQLAQTGHLCIFTLHANTAPQSLERILNFYPKEQHNQILIDIALNLTGIICQRLALKKDKTGRTAVVDLL
INTPAIQDFILKGDLMNISKIMETAKTDGMQTMDQNLFELYRHGIISYEEALRQSVSANNLRLHIQLHKEGKTPELLYDR
VNGLNLIS

Nucleotide

• Length: 1227 bp

>NTDB_id=848872 V5G02_RS09880 WP_047923710.1 1889531..1890757(-) (pilU) [Neisseria gonorrhoeae strain WHO_S2_2024]
ATGAATACCGATAACCTGCACGACATCTTGGACGAAACGGTTCAAGTGTATTCTCAAAAAAACAAAGCCGAATCCGAAAC
CCCGGCCGAAATCGGCGCACACTTCCACCCGCTGCTCGACCGCCTGTGCGAAACCGCAGAAGCACAAAACGCGTCCGACA
TCCTTATCAGCAAAGGATTCCCGCCCTCGTTGAAAATCAACAGCGCATTAACCCCGCAGCCGCAAAAGGCTCTGACGGGC
GAGGAAACCGCCGCCATCGCCGCATCGACGATGAACGCCGAACAATCGGAAATATTCCGGCGCGACGGCGAAATCAACTA
CTCCGTCCAATCGCGCAGCGGCACGCGCTACCGCGCCAACGCCTACTACAGCCAAGGCAGCGCAGGTTTGGTTTTGCGGC
GCATCAACCACGTCATCCCGCAAATGCGGGAATTGGGCTTGCCCGAAAAACTCAAAGACCTCGCCGTCGCACCGCGCGGG
CTGCTGATTATCGTCGGGCCTACCGGTTCGGGCAAATCCACCACGATGGCGACTATGCTCGAACACCGCAACAAAACCCT
GCCCGGCCATATCGTTACCATCGAAGACCCGATTGAGTTTATCTACAAACCGCGCCGCTGCATCTTTACCCAGCGCGAAA
TCGGCGTCGACACCATAAACTGGCAGACGGCGGTACAAAACGCTATGCGCCAATCCCCAGACGTGGTCTGTATCGGCGAA
GTCCGCAGCAGGGAAAGTATGGAATACGCGATGCAGCTCGCCCAAACCGGCCACCTGTGCATTTTTACGCTCCACGCCAA
CACCGCGCCGCAGTCGCTCGAACGCATACTCAACTTCTACCCCAAAGAACAGCACAACCAAATACTGATTGACATCGCCC
TCAATCTGACCGGCATCATCTGCCAACGCCTCGCCCTCAAAAAAGACAAAACGGGCAGGACGGCGGTTGTCGACTTGCTC
ATCAACACGCCCGCCATCCAAGACTTCATCCTGAAGGGCGACCTGATGAACATCAGTAAAATCATGGAAACCGCCAAAAC
CGACGGAATGCAGACGATGGACCAAAACCTTTTCGAACTGTACCGTCACGGCATCATCAGTTACGAAGAAGCCCTGCGCC
AGTCCGTTTCCGCCAACAACCTGCGATTGCACATCCAACTGCACAAAGAAGGCAAAACGCCCGAACTCCTTTACGACAGG
GTCAACGGTCTCAACCTCATTTCCTGA

Domains

Predicted by InterProScan.

• Type II/IV secretion system protein (T2SSE) (49-305)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilU	Acinetobacter baylyi ADP1	44.875	88.48	0.397
pilU	Pseudomonas stutzeri DSM 10701	45.225	87.255	0.395
pilU	Vibrio cholerae strain A1552	47.024	82.353	0.387