Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   QMG97_RS23125 Genome accession   NZ_AP027197
Coordinates   4429845..4430477 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 02E060     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4424845..4435477
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QMG97_RS23100 (F02E060_4433) yheS 4425014..4426927 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  QMG97_RS23105 (F02E060_4434) yheT 4426927..4427949 (+) 1023 WP_000057356.1 hydrolase -
  QMG97_RS23110 (F02E060_4435) yheU 4427943..4428161 (+) 219 WP_000907085.1 YheU family protein -
  QMG97_RS23115 (F02E060_4436) prkB 4428215..4429084 (+) 870 WP_001274680.1 phosphoribulokinase -
  QMG97_RS23120 (F02E060_4437) yhfA 4429139..4429543 (-) 405 WP_001148908.1 OsmC family protein -
  QMG97_RS23125 (F02E060_4438) crp 4429845..4430477 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  QMG97_RS23130 (F02E060_4439) yhfK 4430528..4432618 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  QMG97_RS23135 (F02E060_4440) argD 4432685..4433905 (-) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  QMG97_RS23140 (F02E060_4441) pabA 4433991..4434554 (-) 564 WP_000601850.1 aminodeoxychorismate synthase component 2 -
  QMG97_RS23145 (F02E060_4442) fic 4434586..4435188 (-) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  QMG97_RS23150 (F02E060_4443) yhfG 4435178..4435345 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=84783 QMG97_RS23125 WP_000242755.1 4429845..4430477(+) (crp) [Escherichia coli strain 02E060]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=84783 QMG97_RS23125 WP_000242755.1 4429845..4430477(+) (crp) [Escherichia coli strain 02E060]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment