Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   V5A90_RS16395 Genome accession   NZ_CP144885
Coordinates   3368932..3370953 (-) Length   673 a.a.
NCBI ID   WP_000042533.1    Uniprot ID   Q324B3
Organism   Escherichia coli strain TC_EC10     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 3363932..3375953
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V5A90_RS16360 (V5A90_16370) ybhL 3363936..3364640 (-) 705 WP_000373624.1 Bax inhibitor-1/YccA family protein -
  V5A90_RS16365 (V5A90_16375) moaE 3364777..3365229 (-) 453 WP_000852278.1 molybdopterin synthase catalytic subunit MoaE -
  V5A90_RS16370 (V5A90_16380) moaD 3365231..3365476 (-) 246 WP_000598612.1 molybdopterin synthase sulfur carrier subunit -
  V5A90_RS16375 (V5A90_16385) moaC 3365469..3365954 (-) 486 WP_000080885.1 cyclic pyranopterin monophosphate synthase MoaC -
  V5A90_RS16380 (V5A90_16390) moaB 3365957..3366469 (-) 513 WP_000084639.1 molybdenum cofactor biosynthesis protein B -
  V5A90_RS16385 (V5A90_16395) moaA 3366491..3367480 (-) 990 WP_001305603.1 GTP 3',8-cyclase MoaA -
  V5A90_RS16390 (V5A90_16400) yvcK 3367877..3368785 (+) 909 WP_001305602.1 uridine diphosphate-N-acetylglucosamine-binding protein YvcK -
  V5A90_RS16395 (V5A90_16405) uvrB 3368932..3370953 (-) 2022 WP_000042533.1 excinuclease ABC subunit UvrB Machinery gene
  V5A90_RS16400 (V5A90_16410) bioD 3371532..3372209 (-) 678 WP_000044833.1 dethiobiotin synthase -
  V5A90_RS16405 (V5A90_16415) bioC 3372202..3372957 (-) 756 WP_000246782.1 malonyl-ACP O-methyltransferase BioC -
  V5A90_RS16410 (V5A90_16420) bioF 3372944..3374098 (-) 1155 WP_000118805.1 8-amino-7-oxononanoate synthase -
  V5A90_RS16415 (V5A90_16425) bioB 3374095..3375135 (-) 1041 WP_000951213.1 biotin synthase BioB -

Sequence

Protein


Download         Length: 673 a.a.        Molecular weight: 76226.06 Da        Isoelectric Point: 4.8843

>NTDB_id=847809 V5A90_RS16395 WP_000042533.1 3368932..3370953(-) (uvrB) [Escherichia coli strain TC_EC10]
MSKPFKLNSAFKPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSGKTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEF
FPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKAMLERRDVVVVASVSAIYGLGDPDLYLKMMLH
LTVGMIIDQRAILRRLAELQYARNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFDEEVERLSLFDPLTGQIVSTIPR
FTIYPKTHYVTPRERIVQAMEEIKEELAARRKVLLENNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGE
PPPTLFDYLPADGLLVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYVSATPGNYE
LEKSGGDVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVLVTTLTKRMAEDLTEYLEEHGERVRYLHSDI
DTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPS
MAKAIGETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGRGKSRPIVEPDNVPMDMSPKALQQKIHELE
GLMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS

Nucleotide


Download         Length: 2022 bp        

>NTDB_id=847809 V5A90_RS16395 WP_000042533.1 3368932..3370953(-) (uvrB) [Escherichia coli strain TC_EC10]
ATGAGTAAACCGTTCAAACTGAATTCCGCTTTTAAACCTTCTGGCGATCAGCCAGAGGCGATTCGACGTCTCGAAGAGGG
GCTGGAAGATGGCCTGGCGCACCAGACGTTACTTGGCGTGACTGGCTCCGGGAAAACCTTCACCATTGCCAATGTCATTG
CTGATCTTCAGCGCCCTACCATGGTACTTGCGCCCAACAAAACGCTGGCGGCCCAGTTGTATGGCGAAATGAAAGAGTTC
TTCCCGGAAAACGCGGTGGAATATTTCGTCTCCTACTACGACTACTATCAGCCGGAAGCCTATGTACCGAGTTCCGACAC
CTTCATTGAGAAAGATGCCTCGGTTAACGAACATATTGAACAGATGCGTTTGTCCGCCACCAAAGCGATGCTGGAGCGGC
GTGATGTGGTTGTGGTGGCGTCTGTTTCCGCGATTTATGGTCTGGGCGATCCTGATTTATATCTCAAGATGATGCTCCAT
CTCACGGTCGGCATGATTATCGATCAGCGCGCGATCCTGCGCCGACTGGCGGAGCTGCAATACGCTCGTAATGATCAGGC
ATTCCAGCGTGGTACTTTCCGCGTTCGTGGTGAGGTGATTGATATCTTCCCAGCAGAATCGGATGACATTGCACTTCGCG
TGGAGCTGTTTGACGAGGAAGTGGAACGATTGTCGTTATTTGACCCGCTCACCGGGCAGATTGTTTCCACTATTCCACGT
TTTACCATCTACCCGAAAACGCACTACGTCACGCCGCGCGAGCGCATCGTACAGGCGATGGAAGAGATCAAAGAAGAACT
GGCCGCCAGACGCAAAGTGCTGTTGGAGAATAACAAACTGCTGGAAGAGCAGCGGCTGACCCAGCGTACCCAGTTTGATC
TGGAGATGATGAACGAGCTGGGCTACTGTTCCGGGATTGAGAACTACTCGCGCTTCCTCTCCGGTCGTGGACCGGGTGAG
CCACCGCCGACGCTGTTTGATTACCTGCCTGCCGATGGGCTGCTGGTGGTCGATGAATCACACGTCACCATTCCGCAAAT
TGGCGGCATGTATCGCGGTGACCGGGCGCGTAAAGAGACGCTGGTGGAGTACGGCTTCCGCCTGCCATCAGCGCTGGATA
ACCGTCCGCTGAAATTTGAAGAGTTCGAAGCATTAGCGCCGCAAACCATCTATGTTTCGGCGACGCCGGGTAATTACGAG
CTGGAAAAATCGGGCGGCGATGTGGTGGATCAGGTGGTGCGTCCAACCGGATTGCTGGATCCGATTATCGAAGTGCGGCC
AGTGGCGACACAGGTCGATGATCTTCTATCGGAGATTCGTCAGCGAGCGGCAATTAACGAACGCGTACTGGTTACAACTC
TGACCAAGCGAATGGCGGAAGATCTCACGGAATATCTCGAAGAACACGGCGAGCGCGTGCGTTATCTTCACTCCGATATC
GACACCGTCGAGCGTATGGAGATTATCCGCGACTTGCGTCTGGGCGAGTTCGACGTGCTGGTGGGGATCAACTTACTGCG
CGAAGGTCTGGATATGCCGGAGGTTTCGCTGGTGGCGATCCTCGACGCCGACAAAGAAGGCTTCCTGCGTTCTGAACGTT
CGTTAATCCAGACTATTGGTCGTGCGGCGCGTAACGTTAACGGTAAAGCGATTCTCTACGGCGATAAGATCACCCCGTCA
ATGGCGAAAGCGATTGGCGAAACCGAACGTCGTCGCGAGAAACAGCAGAAGTACAACGAGGAACACGGTATTACGCCGCA
GGGCTTGAACAAGAAAGTGGTCGATATCCTGGCGCTGGGGCAGAACATTGCTAAAACCAAAGCGAAGGGCAGAGGAAAAT
CGCGACCGATTGTTGAGCCGGATAATGTGCCGATGGATATGTCGCCTAAAGCGTTGCAGCAGAAGATCCATGAACTGGAA
GGGTTGATGATGCAACACGCGCAGAATCTGGAGTTCGAAGAAGCGGCGCAAATTCGTGACCAGTTGCATCAGCTGCGTGA
ATTGTTCATTGCCGCGTCGTGA

Domains

Predicted by InterProScan.

UvrB interaction domain (UvrB_inter)

(159-249)

UvrB/uvrC motif (UVR)

(634-667)

Ultra-violet resistance protein B (UvrB)

(552-593)

Type III restriction enzyme, res subunit (ResIII)

(13-92)

Helicase conserved C-terminal domain (Helicase_C)

(436-544)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q324B3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae TIGR4

56.372

99.108

0.559
  uvrB Streptococcus pneumoniae R6

56.222

99.108

0.557
  uvrB Streptococcus pneumoniae D39

56.222

99.108

0.557