Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   V4942_RS00890 Genome accession   NZ_CP144687
Coordinates   155461..157671 (-) Length   736 a.a.
NCBI ID   WP_011172629.1    Uniprot ID   Q72L86
Organism   Thermus thermophilus strain TTHB27_delta_cmr4     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Genomic Context

Location: 150461..162671
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V4942_RS00870 (V4942_00870) sucC 150924..152099 (-) 1176 WP_011172625.1 ADP-forming succinate--CoA ligase subunit beta -
  V4942_RS00875 (V4942_00875) - 152144..153178 (+) 1035 WP_011228011.1 bis-aminopropyl spermidine synthase family protein -
  V4942_RS00880 (V4942_00880) - 153172..154182 (-) 1011 WP_011172627.1 PIN domain-containing protein -
  V4942_RS00885 (V4942_00885) radA 154179..155450 (-) 1272 WP_011172628.1 DNA repair protein RadA Machinery gene
  V4942_RS00890 (V4942_00890) clpC 155461..157671 (-) 2211 WP_011172629.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  V4942_RS00895 (V4942_00895) - 157800..159320 (+) 1521 WP_011172630.1 glycine--tRNA ligase -
  V4942_RS00900 (V4942_00900) - 159501..159737 (+) 237 WP_011172631.1 hypothetical protein -
  V4942_RS00905 (V4942_00905) - 159734..160729 (+) 996 WP_011172632.1 aspartate-semialdehyde dehydrogenase -
  V4942_RS00910 (V4942_00910) - 160716..161423 (-) 708 WP_011172633.1 TlyA family RNA methyltransferase -
  V4942_RS00915 (V4942_00915) - 161441..161752 (+) 312 WP_008631869.1 DUF3234 domain-containing protein -
  V4942_RS00920 (V4942_00920) - 161745..162173 (+) 429 WP_011172634.1 hypothetical protein -

Sequence

Protein


Download         Length: 736 a.a.        Molecular weight: 81424.36 Da        Isoelectric Point: 5.4038

>NTDB_id=847371 V4942_RS00890 WP_011172629.1 155461..157671(-) (clpC) [Thermus thermophilus strain TTHB27_delta_cmr4]
MNRYDDRARLVFHYAREEGSRLGHSMIGPEHLLLGLMREGGTAARILQEYGASLEAMRRMVEELVGRGEGGRTGEPPAIT
PRARRVMELASAEARNMGSPVIGTEHILLGIIREGDGIAYRILSHFAKDVDAIRWRVLAMAEGREREKPVNTPFLDEYGR
DLTKEAREGKLDPVIGRQEEINRVIQILARRTKNNPVLIGDPGVGKTAIVEGLAQAIVEGRVPPILKGARVVAIDLAGVV
AGTKYRGEFEERLRQIIEELKNAKVIAFIDELHTLIGAGGAEGTLDAANILKPALARGEIQVIGATTTGEYHRYIEKDAA
LERRFQPVIVLEPSPEETLEILKGLRPRYEAHHGVIIPDEILELAVKIGIRSLPGRNFPDKAIDLIDEAASRVRLNASLG
LPVAEEEDGTPIVTREDVEAVVDSWGGVYVDDKDDEKLMRLEEELRKRVVGQEEAIRALANALRRARVGLGGRTRVAASF
LFVGQSGVGKTQLAKALAEVLFGSERALIRFDMSEFQEPHSISKLIGAPPGYVGYEQGGRLTEAVRRQPFSVVLLDEIEK
AHPDIYNTFLQVLDEGRLTDGMGRTVDFRRVILIMTSNTGYNVGPAIGFTSKEVDTESPLKALFTPEFLDRLDEVIRFRP
LTEEELVRVAEMMLEDIRKELQARDVQVSFAPELARFLVDQAPKTGSARALRSVLRERIEDPLAVALLRKPTGRIHVSVE
GGQVAFHEVEGEELLV

Nucleotide


Download         Length: 2211 bp        

>NTDB_id=847371 V4942_RS00890 WP_011172629.1 155461..157671(-) (clpC) [Thermus thermophilus strain TTHB27_delta_cmr4]
ATGAACCGATACGACGACCGCGCCAGGCTGGTCTTTCACTACGCAAGAGAGGAGGGGAGCCGCTTAGGCCACTCCATGAT
CGGCCCGGAGCACCTCCTCCTGGGCCTGATGCGCGAGGGGGGTACGGCGGCCCGCATCCTCCAGGAGTACGGCGCGAGCC
TCGAGGCCATGCGCCGCATGGTGGAGGAGCTGGTGGGCCGGGGGGAGGGCGGGCGCACCGGGGAGCCCCCCGCCATCACC
CCGAGGGCGAGGCGGGTCATGGAGCTCGCCAGCGCCGAGGCCCGCAACATGGGCTCCCCCGTCATCGGCACGGAGCACAT
CCTCCTCGGCATCATCCGGGAGGGGGACGGGATCGCCTACCGCATCCTCAGCCACTTCGCCAAGGACGTGGACGCCATCC
GCTGGAGGGTCCTGGCCATGGCCGAGGGCCGCGAGCGGGAAAAGCCCGTGAACACCCCCTTCCTGGACGAGTACGGCCGC
GACCTCACCAAGGAGGCCCGGGAAGGGAAGCTGGACCCGGTGATCGGCCGCCAGGAGGAGATCAACCGGGTGATCCAGAT
CCTCGCCCGGCGCACCAAGAACAACCCCGTGCTCATCGGCGACCCCGGGGTGGGCAAGACGGCCATCGTGGAGGGCCTGG
CCCAGGCCATCGTGGAGGGCCGGGTCCCCCCCATCCTCAAGGGGGCCCGGGTGGTGGCCATTGACCTCGCCGGAGTGGTG
GCGGGGACCAAGTACCGGGGCGAGTTTGAGGAGCGCCTGCGGCAGATCATTGAGGAGCTCAAGAACGCCAAGGTCATCGC
CTTCATTGACGAGCTTCACACCCTGATCGGGGCGGGCGGGGCCGAGGGCACCCTGGACGCCGCCAACATCCTCAAGCCCG
CCCTGGCCCGCGGGGAGATCCAGGTGATCGGGGCCACCACCACCGGGGAGTACCACCGCTACATAGAGAAGGACGCGGCC
CTGGAGCGGCGCTTCCAGCCGGTGATCGTCCTCGAGCCCTCCCCCGAGGAAACCCTGGAGATCCTCAAGGGCCTCCGCCC
CCGCTACGAGGCCCACCACGGGGTGATCATCCCCGACGAGATCCTGGAGCTTGCGGTGAAGATCGGGATCCGCTCGCTTC
CCGGGCGCAACTTCCCCGACAAGGCCATTGACCTCATTGACGAGGCGGCCTCGAGGGTGCGCCTCAACGCCTCCTTGGGC
CTCCCCGTGGCGGAGGAAGAGGACGGCACCCCCATCGTCACCCGGGAGGACGTGGAAGCGGTGGTGGACTCCTGGGGCGG
GGTCTACGTGGACGACAAGGACGACGAGAAACTCATGCGCCTGGAGGAGGAGCTCAGGAAGCGGGTGGTGGGCCAGGAGG
AGGCCATCCGCGCCCTGGCGAACGCCCTCCGCCGGGCCCGGGTGGGGCTTGGGGGAAGGACCCGGGTGGCGGCGAGCTTC
CTCTTCGTGGGGCAAAGCGGCGTGGGCAAGACCCAGCTCGCCAAGGCCCTGGCCGAGGTCCTCTTCGGCTCGGAGAGGGC
CCTCATCCGCTTTGACATGTCCGAGTTCCAGGAGCCCCACTCCATCTCCAAGCTCATCGGGGCCCCGCCGGGCTATGTGG
GCTACGAGCAGGGGGGCCGCCTCACCGAGGCCGTGCGCCGCCAACCCTTCAGCGTGGTCCTCCTGGACGAGATTGAGAAG
GCCCACCCCGACATCTACAACACCTTCCTCCAGGTGCTGGACGAGGGCCGCCTCACGGACGGCATGGGCCGCACCGTGGA
CTTCCGCCGGGTCATCCTCATCATGACCTCCAACACCGGCTACAACGTGGGCCCCGCCATCGGCTTCACCTCCAAGGAGG
TGGACACGGAGTCCCCCCTGAAGGCCCTCTTCACCCCCGAGTTTCTGGACCGGCTGGACGAGGTCATCCGCTTCCGACCC
CTCACGGAGGAGGAGCTGGTGCGGGTGGCCGAGATGATGCTGGAGGACATCCGCAAGGAGCTCCAGGCCCGGGACGTCCA
GGTGAGCTTCGCCCCCGAATTGGCCCGCTTCCTGGTGGACCAGGCTCCCAAGACGGGGAGCGCCCGCGCCCTGCGGAGCG
TCCTAAGGGAGCGCATAGAGGACCCCTTGGCCGTCGCCCTCCTGCGGAAGCCCACGGGCCGGATCCACGTGAGCGTGGAG
GGAGGTCAGGTGGCCTTCCACGAGGTGGAGGGGGAAGAGCTCCTCGTCTAG

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(641-711)

ATPase family associated with various cellular activities (AAA) (AAA)

(197-330)

AAA domain (Cdc48 subfamily) (AAA_2)

(478-635)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(15-66)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(90-140)

AAA lid domain (AAA_lid_9)

(334-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q72L86

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Bacillus subtilis subsp. subtilis str. 168

48.02

100

0.527
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

42.588

100

0.461
  clpC Streptococcus pneumoniae Rx1

41.762

100

0.444
  clpC Streptococcus pneumoniae D39

41.762

100

0.444
  clpC Streptococcus pneumoniae TIGR4

41.379

100

0.44
  clpC Streptococcus thermophilus LMD-9

39.698

100

0.429
  clpC Streptococcus thermophilus LMG 18311

39.447

100

0.427
  clpC Streptococcus mutans UA159

39.544

100

0.424
  clpE Streptococcus mutans UA159

48.445

83.016

0.402
  clpC Lactococcus lactis subsp. cremoris KW2

47.463

83.016

0.394
  clpE Streptococcus pneumoniae D39

47.222

83.152

0.393
  clpE Streptococcus pneumoniae Rx1

47.222

83.152

0.393
  clpE Streptococcus pneumoniae R6

47.222

83.152

0.393
  clpE Streptococcus pneumoniae TIGR4

47.059

83.152

0.391
  clpA Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

38.968

94.837

0.37