Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   VM636_RS23065 Genome accession   NZ_CP144555
Coordinates   5251478..5253610 (+) Length   710 a.a.
NCBI ID   WP_338485542.1    Uniprot ID   -
Organism   Streptomyces sp. SCSIO 75703     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 5246478..5258610
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VM636_RS23040 (VM636_23040) - 5247128..5248033 (-) 906 WP_338486431.1 pseudouridine-5'-phosphate glycosidase -
  VM636_RS23045 (VM636_23045) - 5248320..5248748 (+) 429 WP_338485534.1 VOC family protein -
  VM636_RS23050 (VM636_23050) - 5248789..5249343 (-) 555 WP_338485536.1 methylated-DNA--[protein]-cysteine S-methyltransferase -
  VM636_RS23055 (VM636_23055) - 5249403..5250290 (-) 888 WP_338485538.1 glycerophosphodiester phosphodiesterase family protein -
  VM636_RS23060 (VM636_23060) - 5250569..5251438 (+) 870 WP_338485540.1 MHYT domain-containing protein -
  VM636_RS23065 (VM636_23065) uvrB 5251478..5253610 (+) 2133 WP_338485542.1 excinuclease ABC subunit UvrB Machinery gene
  VM636_RS23070 (VM636_23070) - 5253756..5254334 (+) 579 WP_030423143.1 TerD family protein -
  VM636_RS23075 (VM636_23075) - 5254425..5256389 (+) 1965 WP_338485544.1 TerD family protein -
  VM636_RS23080 (VM636_23080) - 5256844..5257845 (+) 1002 WP_338485545.1 TerC family protein -

Sequence

Protein


Download         Length: 710 a.a.        Molecular weight: 79936.38 Da        Isoelectric Point: 4.6905

>NTDB_id=847144 VM636_RS23065 WP_338485542.1 5251478..5253610(+) (uvrB) [Streptomyces sp. SCSIO 75703]
MRPVSQIERTVAPFEVVSPYQPSGDQPAAIAELARRIEAGEKDVVLLGATGTGKSATTAWVIEKLQRPTLVMAPNKTLAA
QLANEFRELLPNNAVEYFVSYYDYYQPEAYVPQSDTYIEKDSSINEEVERLRHSATNSLLTRRDVVVVASVSCIYGLGTP
QEYVDRMVPLRVGDEFDRDELLRRFVDIQYTRNDMAFTRGTFRVRGDTIEIFPVYEELAVRIEMFGDEIEALSTLHPLTG
EIVSDDRQLYVFPASHYVAGPERMERAVNDIEKELAERLADLEKQGKLLEAQRLRMRTTYDIEMLRQIGSCSGVENYSMH
FDGRSPGSPPNTLLDYFPDDFLLVIDESHVTVPQIGAMYEGDASRKRTLVDHGFRLPSALDNRPLKWEEFQERVGQAVYL
SATPGTYELSRSDGAVEQIIRPTGLVDPEVVVKPTEGQIDDLVHEIRERTEKDERVLVTTLTKKMAEDLTDYFVELGIQV
RYLHSDVDTLRRVELLRELRTGEYDVLVGINLLREGLDLPEVSLVAILDADKEGFLRSGTSLIQTIGRAARNVSGQVHMY
ADKITPAMEKAIDETNRRREKQIAFNQANGIDPQPLRKKINDIVAQIAREDVDTEQLLGSGYRQSLDGKAPKAPVPALGG
QQTATKARGRGKETVPTDRPAAELAEQIEELTTRMRAAAADLQFEIAARLRDEVSEMKKELRQMREAGLA

Nucleotide


Download         Length: 2133 bp        

>NTDB_id=847144 VM636_RS23065 WP_338485542.1 5251478..5253610(+) (uvrB) [Streptomyces sp. SCSIO 75703]
ATGCGGCCCGTTTCCCAGATCGAACGCACGGTGGCGCCCTTCGAGGTCGTCAGCCCCTACCAGCCGAGCGGCGACCAGCC
CGCGGCCATCGCCGAGCTCGCCCGGCGCATCGAAGCAGGCGAGAAGGACGTCGTGCTCCTCGGCGCGACCGGCACCGGCA
AGTCCGCCACCACCGCGTGGGTGATCGAGAAGCTCCAGCGGCCCACCCTCGTGATGGCGCCCAACAAGACGCTGGCCGCC
CAGCTGGCGAACGAGTTCCGCGAGCTGCTGCCGAACAACGCCGTCGAGTACTTCGTCTCGTACTACGACTACTACCAGCC
CGAGGCGTACGTCCCGCAGTCGGACACCTACATCGAGAAGGACTCCTCGATCAACGAGGAGGTGGAGCGCCTGCGCCACT
CCGCCACCAACTCGCTGCTCACCCGCCGCGACGTCGTCGTGGTCGCCTCCGTCTCCTGCATCTACGGCCTCGGCACACCC
CAGGAGTACGTGGACCGGATGGTCCCGCTGCGGGTCGGCGACGAGTTCGACCGCGACGAACTGCTGCGCCGCTTCGTCGA
CATCCAGTACACGCGCAACGACATGGCCTTCACCCGCGGCACCTTCCGGGTACGCGGCGACACCATCGAGATCTTCCCGG
TCTACGAGGAACTGGCCGTCCGCATCGAGATGTTCGGTGACGAGATCGAGGCCCTCTCCACCCTGCACCCGCTCACCGGC
GAGATCGTCAGCGACGACCGGCAGCTCTACGTGTTCCCCGCCTCCCACTACGTGGCCGGCCCCGAACGCATGGAGCGGGC
CGTCAACGACATCGAGAAGGAACTGGCCGAACGCCTGGCCGACCTGGAGAAGCAGGGCAAGCTCCTGGAGGCCCAGCGGC
TGCGGATGCGCACCACCTACGACATCGAGATGCTCCGCCAGATCGGCTCCTGCTCCGGCGTGGAGAACTACTCCATGCAC
TTCGACGGCCGCTCGCCCGGCTCCCCGCCGAACACCCTGCTGGACTACTTCCCGGACGACTTCCTGCTGGTCATCGACGA
GTCGCACGTCACCGTGCCCCAGATCGGCGCCATGTACGAAGGCGACGCCTCGCGCAAGCGGACCCTCGTCGACCACGGTT
TCCGGCTGCCCTCCGCGCTGGACAACCGCCCGCTGAAGTGGGAGGAGTTCCAGGAGCGCGTCGGTCAGGCCGTCTACCTG
TCGGCCACCCCCGGCACCTACGAACTCTCCCGCTCCGACGGCGCCGTGGAGCAGATCATCCGCCCCACCGGCCTCGTCGA
CCCGGAGGTCGTCGTCAAGCCCACCGAGGGCCAGATCGACGACCTGGTGCACGAGATCCGCGAGCGGACCGAGAAGGACG
AACGCGTCCTCGTCACCACCCTCACCAAGAAGATGGCCGAGGACCTCACCGACTACTTCGTCGAACTCGGCATCCAGGTC
CGCTACCTGCACAGCGACGTCGACACCCTGCGCCGCGTGGAACTCCTGCGCGAACTGCGCACCGGCGAGTACGACGTACT
GGTCGGCATCAACCTCCTGCGCGAGGGCCTGGACCTGCCCGAGGTCTCCCTGGTGGCGATCCTCGACGCCGACAAGGAGG
GCTTCCTGCGCTCCGGAACCTCCCTCATCCAGACCATCGGCCGTGCCGCGCGCAACGTCTCCGGTCAGGTCCACATGTAC
GCGGACAAGATCACGCCGGCGATGGAGAAGGCCATCGACGAGACCAACCGGCGCCGCGAGAAGCAGATCGCCTTCAACCA
GGCGAACGGCATCGACCCGCAGCCGCTCCGCAAGAAGATCAACGACATCGTCGCGCAGATCGCCCGCGAGGACGTCGACA
CCGAGCAGCTCCTCGGCTCCGGCTACCGCCAGTCCCTGGACGGCAAGGCGCCCAAGGCGCCCGTGCCCGCCCTCGGTGGG
CAGCAGACGGCCACGAAGGCCAGGGGCCGGGGCAAGGAGACCGTGCCGACCGACCGGCCCGCCGCGGAGCTGGCCGAGCA
GATCGAGGAGCTGACCACGCGGATGCGGGCCGCCGCCGCCGACCTCCAGTTCGAGATCGCGGCCCGGCTGCGCGACGAGG
TCTCCGAGATGAAGAAGGAGCTGCGCCAGATGAGGGAGGCGGGCCTCGCCTGA

Domains

Predicted by InterProScan.

Helicase conserved C-terminal domain (Helicase_C)

(441-551)

UvrB/uvrC motif (UVR)

(666-699)

Type III restriction enzyme, res subunit (ResIII)

(25-134)

UvrB interaction domain (UvrB_inter)

(169-257)

Ultra-violet resistance protein B (UvrB)

(559-600)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae TIGR4

58.017

96.62

0.561
  uvrB Streptococcus pneumoniae R6

58.017

96.62

0.561
  uvrB Streptococcus pneumoniae D39

58.017

96.62

0.561