Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   QQM35_RS10595 Genome accession   NZ_CP128355
Coordinates   2111614..2112243 (-) Length   209 a.a.
NCBI ID   WP_251518488.1    Uniprot ID   -
Organism   Staphylococcus hsinchuensis strain H164     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2106614..2117243
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QQM35_RS10565 (QQM35_10555) - 2106628..2107158 (-) 531 WP_251518504.1 acyl-CoA thioesterase -
  QQM35_RS10570 (QQM35_10560) - 2107193..2108431 (-) 1239 WP_251518502.1 aminopeptidase -
  QQM35_RS10575 (QQM35_10565) - 2108445..2108648 (-) 204 WP_251518501.1 DUF1128 family protein -
  QQM35_RS10580 (QQM35_10570) - 2109221..2109685 (+) 465 WP_251942705.1 low molecular weight protein-tyrosine-phosphatase -
  QQM35_RS10585 (QQM35_10575) - 2109692..2109976 (+) 285 WP_251518492.1 YtxH domain-containing protein -
  QQM35_RS10590 (QQM35_10580) - 2110300..2111493 (+) 1194 WP_251518490.1 YihY/virulence factor BrkB family protein -
  QQM35_RS10595 (QQM35_10585) vraR 2111614..2112243 (-) 630 WP_251518488.1 response regulator transcription factor Regulator
  QQM35_RS10600 (QQM35_10590) vraS 2112233..2113276 (-) 1044 WP_251518486.1 sensor histidine kinase Regulator
  QQM35_RS10605 (QQM35_10595) liaF 2113273..2113974 (-) 702 WP_251518484.1 cell wall-active antibiotics response protein LiaF -
  QQM35_RS10610 (QQM35_10600) - 2113993..2114379 (-) 387 WP_251518482.1 hypothetical protein -
  QQM35_RS10615 (QQM35_10605) map 2114484..2115236 (-) 753 WP_251518480.1 type I methionyl aminopeptidase -
  QQM35_RS10620 (QQM35_10610) - 2115403..2116389 (+) 987 WP_251518478.1 aromatic acid exporter family protein -
  QQM35_RS10625 (QQM35_10615) - 2116481..2117200 (-) 720 WP_251518476.1 glutamine amidotransferase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23688.22 Da        Isoelectric Point: 4.9144

>NTDB_id=847001 QQM35_RS10595 WP_251518488.1 2111614..2112243(-) (vraR) [Staphylococcus hsinchuensis strain H164]
MPIKVLFVDDHEMVRIGISSYLSTQPDIEVVGEGKSGKEAIEKAHELHPDLILMDLLMDDMDGVEATEQVKKDLPHTKVL
MLTSYIEDNEVYRALDSGVDSYILKTTSASDIAEAIRKTHEGESVFEAEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=847001 QQM35_RS10595 WP_251518488.1 2111614..2112243(-) (vraR) [Staphylococcus hsinchuensis strain H164]
ATGCCGATTAAAGTATTATTTGTTGATGATCATGAGATGGTTCGCATTGGTATTTCAAGTTATTTATCTACGCAACCAGA
TATTGAAGTAGTTGGGGAAGGGAAATCTGGTAAAGAAGCAATTGAAAAAGCCCATGAACTTCATCCGGATTTAATTTTAA
TGGATTTGCTCATGGATGACATGGATGGGGTAGAAGCGACAGAACAAGTTAAAAAAGATTTACCTCATACGAAAGTATTG
ATGTTAACAAGTTATATCGAGGATAACGAAGTGTACCGTGCTCTAGATTCTGGCGTTGATAGTTATATCTTAAAGACAAC
GAGTGCGAGTGATATTGCAGAAGCGATTCGTAAAACTCATGAAGGTGAATCAGTCTTTGAAGCAGAAGTGCTCGTGAAAA
TGCGTAATAGAATGAAAAAACGTGCTGAGTTATATGAAATGTTAACTGAACGTGAAATGGAGATACTACTATTAATTGCT
AAAGGTTATTCTAATCAAGAAATTGCAAGCGCCTCACATATTACGATCAAAACGGTTAAAACCCATGTAAGTAATATCTT
AAGTAAACTAGAAGTCCAAGATCGAACACAAGCTGTTATTTATGCTTTCCAACACAACTTAATACAGTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-117)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

90.909

100

0.909
  degU Bacillus subtilis subsp. subtilis str. 168

36.161

100

0.388