Detailed information NTG0847002

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: QQM35_RS10600
• Genome accession: NZ_CP128355
• Coordinates: 2112233..2113276 (-)
• Length: 347 a.a.
• NCBI ID: WP_251518486.1
• Uniprot ID: -
• Organism: Staphylococcus hsinchuensis strain H164
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2107233..2118276

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QQM35_RS10575 (QQM35_10565)	-	2108445..2108648 (-)	204	WP_251518501.1	DUF1128 family protein	-
QQM35_RS10580 (QQM35_10570)	-	2109221..2109685 (+)	465	WP_251942705.1	low molecular weight protein-tyrosine-phosphatase	-
QQM35_RS10585 (QQM35_10575)	-	2109692..2109976 (+)	285	WP_251518492.1	YtxH domain-containing protein	-
QQM35_RS10590 (QQM35_10580)	-	2110300..2111493 (+)	1194	WP_251518490.1	YihY/virulence factor BrkB family protein	-
QQM35_RS10595 (QQM35_10585)	vraR	2111614..2112243 (-)	630	WP_251518488.1	response regulator transcription factor	Regulator
QQM35_RS10600 (QQM35_10590)	vraS	2112233..2113276 (-)	1044	WP_251518486.1	sensor histidine kinase	Regulator
QQM35_RS10605 (QQM35_10595)	liaF	2113273..2113974 (-)	702	WP_251518484.1	cell wall-active antibiotics response protein LiaF	-
QQM35_RS10610 (QQM35_10600)	-	2113993..2114379 (-)	387	WP_251518482.1	hypothetical protein	-
QQM35_RS10615 (QQM35_10605)	map	2114484..2115236 (-)	753	WP_251518480.1	type I methionyl aminopeptidase	-
QQM35_RS10620 (QQM35_10610)	-	2115403..2116389 (+)	987	WP_251518478.1	aromatic acid exporter family protein	-
QQM35_RS10625 (QQM35_10615)	-	2116481..2117200 (-)	720	WP_251518476.1	glutamine amidotransferase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39945.39 Da
• Isoelectric Point: 6.4218

>NTDB_id=847002 QQM35_RS10600 WP_251518486.1 2112233..2113276(-) (vraS) [Staphylococcus hsinchuensis strain H164]
MNHYIRAIGSMLILVYSTFFAIFFIDKVFVNIMYFQGMFYTQIFGIPVLLFVNLLVILLCIIVGSVLAYKINQQNHWLQT
QIERSIEGQTVGINDKNIELYNETIELYQTLVPLNQEVHKLRMKTQNLTNESYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLSQQIPTLEKMIQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLKKKVPMKVVHDI
EEFEVPKGIEDHLFRITQEAISNTLRHSQGTKVTVELFNKDKYLLLRIQDDGKGFNVDDKVEQSYGLKNMRERAIEIGAN
FHIVSLPDSGTRVEVKAPLNKEDSDAD

Nucleotide

• Length: 1044 bp

>NTDB_id=847002 QQM35_RS10600 WP_251518486.1 2112233..2113276(-) (vraS) [Staphylococcus hsinchuensis strain H164]
ATGAATCACTATATAAGAGCAATTGGATCAATGCTAATATTAGTTTATAGCACGTTTTTTGCTATCTTTTTTATCGATAA
AGTTTTTGTTAACATAATGTACTTCCAAGGTATGTTTTATACTCAAATTTTTGGAATACCCGTATTATTATTTGTTAACT
TATTAGTTATATTATTATGTATTATTGTAGGGTCAGTATTAGCTTACAAAATTAATCAACAAAATCATTGGTTACAAACG
CAAATAGAACGTTCCATTGAAGGACAGACAGTCGGTATAAACGATAAAAACATCGAACTGTACAATGAAACGATTGAGTT
ATATCAGACATTAGTACCGTTAAATCAAGAAGTCCACAAACTGAGAATGAAGACCCAAAATTTAACAAACGAATCTTATA
ATATTAATGACGTTAAAGTAAAGAAAATTATAGAAGATGAACGACAAAGACTTGCACGTGAATTACATGATTCAGTGAGT
CAACAATTATTTGCAGCAAGCATGATGTTATCAGCTATTAAAGAGACGAAACTTGAGCCACCATTAAGCCAACAAATCCC
TACACTTGAAAAGATGATTCAAGATTCGCAACTAGAAATGAGAGCATTACTATTGCATTTAAGACCAATTGGCTTAAAAG
ATAAGTCACTTGGAGAAGGAATAAAGGATTTAGTAATTGATTTAAAGAAAAAAGTGCCAATGAAAGTGGTACACGATATA
GAAGAATTTGAAGTTCCTAAAGGGATAGAGGATCACTTATTCAGAATTACGCAAGAGGCGATATCTAATACTTTGAGACA
CTCTCAAGGTACAAAAGTGACCGTTGAACTATTTAATAAAGATAAGTATTTATTGCTACGTATTCAAGATGATGGGAAAG
GCTTTAATGTTGATGACAAAGTTGAACAAAGTTACGGTCTTAAAAACATGAGAGAAAGAGCGATAGAAATTGGTGCAAAC
TTTCATATCGTATCGTTACCTGATTCAGGTACGAGAGTTGAAGTTAAAGCACCTTTAAATAAGGAGGATTCAGATGCCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	87.32	100	0.873