Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QMG74_RS25735 Genome accession   NZ_AP027185
Coordinates   5012806..5013327 (+) Length   173 a.a.
NCBI ID   WP_000633683.1    Uniprot ID   -
Organism   Escherichia coli strain NIID080884     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 5007806..5018327
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QMG74_RS25705 (NI080884_4948) emrD 5008288..5009472 (-) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  QMG74_RS25710 ysdE 5009554..5009628 (+) 75 WP_211180519.1 protein YsdE -
  QMG74_RS25715 (NI080884_4949) tisB 5009891..5009980 (-) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  QMG74_RS25720 (NI080884_4950) ivbL 5010545..5010643 (+) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  QMG74_RS25725 (NI080884_4951) ilvB 5010749..5012437 (+) 1689 WP_000168497.1 acetolactate synthase large subunit -
  QMG74_RS25730 (NI080884_4952) ilvN 5012441..5012731 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  QMG74_RS25735 (NI080884_4953) letA 5012806..5013327 (+) 522 WP_000633683.1 transcriptional regulator UhpA Regulator
  QMG74_RS25740 (NI080884_4954) uhpB 5013327..5014829 (+) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  QMG74_RS25745 (NI080884_4955) uhpC 5014839..5016158 (+) 1320 WP_001341770.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  QMG74_RS25750 (NI080884_4956) uhpT 5016414..5017805 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 173 a.a.        Molecular weight: 18565.67 Da        Isoelectric Point: 6.9500

>NTDB_id=84557 QMG74_RS25735 WP_000633683.1 5012806..5013327(+) (letA) [Escherichia coli strain NIID080884]
MITVALIDDHLIVRSGFAQLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSVHDSPALVEQALNAGARGFLSKRC
SPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAAELGLSPKTVHVHRANLMEKLGVS
NDVELARRMFDGW

Nucleotide


Download         Length: 522 bp        

>NTDB_id=84557 QMG74_RS25735 WP_000633683.1 5012806..5013327(+) (letA) [Escherichia coli strain NIID080884]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCCGGGGCGCGGTGTGCAGGT
GTGTATTTGCGATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAA
TGCTCTCTGTTCATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTCTCCAAACGCTGT
AGCCCTGACGAACTGATTGCGGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACT
GGCATCCGGTCGTCAGGACCCGCTAACCAAACGCGAACGGCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAG
AGATTGCTGCCGAACTGGGCTTGTCGCCGAAAACGGTGCACGTCCATCGCGCCAACCTGATGGAAAAACTGGGTGTCAGT
AACGACGTAGAGCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(17-89)

Bacterial regulatory proteins, luxR family (GerE)

(113-168)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

33.5

100

0.387
  letA Legionella pneumophila strain ERS1305867

33.5

100

0.387
  degU Bacillus subtilis subsp. subtilis str. 168

29.596

100

0.381

Multiple sequence alignment