Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   L6410_RS05980 Genome accession   NZ_AP024276
Coordinates   1187865..1188605 (-) Length   246 a.a.
NCBI ID   WP_222381069.1    Uniprot ID   -
Organism   Streptococcus parasuis strain SUT-286     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1182865..1193605
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L6410_RS05960 - 1184084..1185445 (+) 1362 Protein_1143 bacteriocin secretion accessory protein -
  L6410_RS05965 (SUT286_11450) - 1185544..1185699 (+) 156 WP_237395091.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  L6410_RS05970 (SUT286_11460) tnpA 1185908..1186372 (+) 465 WP_029172398.1 IS200/IS605-like element ISSsu4 family transposase -
  L6410_RS05975 (SUT286_11470) - 1186508..1187854 (-) 1347 WP_237395092.1 GHKL domain-containing protein -
  L6410_RS05980 (SUT286_11480) comE/blpR 1187865..1188605 (-) 741 WP_222381069.1 response regulator transcription factor Regulator
  L6410_RS05985 (SUT286_11490) - 1188607..1188948 (-) 342 WP_222381070.1 LytR/AlgR family response regulator transcription factor -
  L6410_RS05990 (SUT286_11500) - 1189147..1189542 (+) 396 WP_237395093.1 hypothetical protein -
  L6410_RS05995 (SUT286_11510) - 1189478..1189888 (-) 411 Protein_1150 helical hairpin domain-containing protein -
  L6410_RS06000 - 1189938..1190785 (+) 848 WP_237395094.1 IS630 family transposase -
  L6410_RS06005 (SUT286_11530) - 1191001..1191468 (-) 468 WP_172130292.1 8-oxo-dGTP diphosphatase -

Sequence

Protein


Download         Length: 246 a.a.        Molecular weight: 28919.26 Da        Isoelectric Point: 8.4156

>NTDB_id=84480 L6410_RS05980 WP_222381069.1 1187865..1188605(-) (comE/blpR) [Streptococcus parasuis strain SUT-286]
MNIFVLEDDFKQQARIEKIITKLLEKHNIVPKKFEISGKPHQLLQAIEEKGVHQLFFLDIEIKEDELKGLQVAKQIREID
PYASIVFVTTHSEFMPLSFRYQVSALDYIDKELGATEFESRIEAALFHVYGKNHKAVAEDSFYFKSKYAQVQYPFNEVYY
IETSPRPHRVILYTKTDRMEFTASLSDILKQDKRLLQCHRSFAINPRNVVKVDRQEKQVYFPNSSTCLVSRQKLESTLAV
IDRLHR

Nucleotide


Download         Length: 741 bp        

>NTDB_id=84480 L6410_RS05980 WP_222381069.1 1187865..1188605(-) (comE/blpR) [Streptococcus parasuis strain SUT-286]
ATGAATATCTTTGTATTGGAAGATGATTTTAAGCAACAAGCGAGAATTGAGAAGATTATTACTAAGCTGTTAGAAAAGCA
CAACATCGTTCCGAAAAAATTTGAAATTTCAGGAAAACCTCATCAGCTACTTCAAGCAATAGAAGAAAAAGGAGTACATC
AGCTCTTCTTTTTAGATATTGAGATTAAGGAAGACGAACTAAAAGGACTTCAAGTCGCTAAACAAATTAGAGAGATTGAC
CCTTATGCTAGTATTGTTTTTGTGACAACACACTCCGAGTTTATGCCCTTATCTTTCAGGTACCAGGTATCTGCCCTAGA
TTATATTGATAAAGAACTTGGAGCTACTGAATTTGAATCGCGAATAGAAGCTGCTTTATTTCATGTTTATGGTAAGAATC
ATAAAGCAGTGGCGGAGGATTCATTTTATTTTAAATCTAAATATGCCCAAGTACAGTACCCCTTTAATGAAGTTTACTAC
ATCGAGACTTCTCCACGTCCTCATCGTGTTATCCTTTACACCAAAACAGACCGAATGGAGTTTACAGCAAGTTTATCAGA
TATTCTGAAACAAGATAAGCGACTGTTACAATGTCATCGTTCATTTGCAATCAATCCGAGGAATGTTGTTAAGGTTGATC
GGCAAGAAAAGCAGGTCTATTTTCCAAATAGCTCTACCTGTCTTGTCTCAAGGCAAAAGCTAGAATCAACTTTAGCTGTT
ATTGATAGACTGCATAGATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-235)

Response regulator receiver domain (Response_reg)

(3-122)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

54.132

98.374

0.533
  comE/comE1 Streptococcus equinus JB1

43.096

97.154

0.419
  comE/comE2 Streptococcus equinus JB1

38.115

99.187

0.378

Multiple sequence alignment