Detailed information NTG0084464

Bioinformatically predicted

Overview

• Name: comFA/cflA
• Type: Machinery gene
• Locus tag: L6410_RS01840
• Genome accession: NZ_AP024276
• Coordinates: 365456..366757 (+)
• Length: 433 a.a.
• NCBI ID: WP_237395707.1
• Uniprot ID: -
• Organism: Streptococcus parasuis strain SUT-286
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	365087..365437	365456..366757	flank	19

Gene organization within MGE regions

Location: 365087..366757

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
L6410_RS01840 (SUT286_03420)	comFA/cflA	365456..366757 (+)	1302	WP_237395707.1	DEAD/DEAH box helicase	Machinery gene

Sequence

Protein

• Length: 433 a.a.
• Molecular weight: 49059.70 Da
• Isoelectric Point: 8.7349

>NTDB_id=84464 L6410_RS01840 WP_237395707.1 365456..366757(+) (comFA/cflA) [Streptococcus parasuis strain SUT-286]
MYYFCFILLYHGRLFTKYQLTSEERERAKTISSVVGKNSCFRCGTSFEEENKLPNAAYYCRACLLLGRVRTDEKLYYFPQ
KDFSMNACLLWKGALTDWQQRISDGLVANVEKRQATLVHAVTGAGKTEMMYHAVASVINKGGAVCLASPRIDVCIELYKR
LQNDFSVPISLLHGESDPYFRTPLVVATTHQLLKFYQAFDLVLIDEVDAFPYADNPILYQAADNAVKVDGVLVFLTATST
DELDKKVKSGKLQKLSLPRRFHGNPLVVPQKVWFSKFDTYLKKNKLVPKLRNAIQKQRETGYPLLIFVPEISKGLEFTSI
MEQIFPEETIGFVSSQTDNRLEIVEGFRNKEITILISTTILERGVTFPGVDVIVVQANHYLYTSSSLVQISGRVGRSMDR
PTGLLLFFHEGSTRSIEKAIAEIKQMNKEAGYV

Nucleotide

• Length: 1302 bp

>NTDB_id=84464 L6410_RS01840 WP_237395707.1 365456..366757(+) (comFA/cflA) [Streptococcus parasuis strain SUT-286]
ATGTACTATTTTTGTTTCATTTTACTATACCATGGAAGACTTTTTACTAAATACCAATTAACGTCAGAAGAAAGAGAAAG
AGCAAAAACAATTTCCAGTGTAGTAGGAAAGAATTCTTGTTTCCGATGCGGTACATCGTTTGAGGAAGAAAACAAGCTGC
CAAATGCTGCGTATTATTGTCGGGCTTGTCTCCTTTTGGGGAGAGTTCGAACAGATGAGAAACTCTACTATTTTCCACAG
AAAGATTTTTCAATGAATGCTTGTCTTCTATGGAAGGGGGCGCTGACCGATTGGCAACAACGAATATCAGATGGATTAGT
TGCGAATGTGGAAAAACGACAAGCAACGCTTGTTCATGCTGTAACAGGTGCGGGCAAAACGGAAATGATGTACCATGCTG
TTGCATCAGTAATTAATAAAGGAGGTGCTGTATGTCTAGCCAGTCCAAGAATTGATGTTTGTATTGAACTCTACAAGCGA
CTACAAAATGATTTTTCGGTCCCAATTAGTCTGCTACATGGGGAATCAGACCCATATTTCAGAACGCCACTCGTTGTTGC
GACCACTCATCAGTTGTTAAAGTTCTACCAGGCATTTGATTTGGTCTTGATCGATGAAGTAGATGCTTTCCCCTATGCAG
ACAACCCTATATTATATCAAGCAGCAGATAATGCAGTTAAAGTAGACGGAGTTTTAGTATTTTTAACAGCAACCTCTACG
GATGAATTAGATAAAAAAGTCAAATCAGGCAAATTACAAAAACTCAGTCTCCCTAGACGTTTTCATGGAAATCCGCTTGT
GGTTCCGCAAAAGGTCTGGTTTTCCAAATTCGATACATATTTGAAGAAAAACAAATTAGTTCCAAAACTCAGAAATGCCA
TTCAAAAGCAAAGAGAAACAGGCTATCCATTACTTATTTTTGTACCAGAAATTTCGAAAGGATTGGAATTTACAAGTATA
ATGGAACAAATCTTTCCAGAAGAAACAATTGGTTTTGTATCGAGTCAGACAGACAATAGGCTTGAAATAGTGGAAGGATT
TCGCAACAAAGAAATTACAATTTTAATTTCTACTACAATCTTAGAGCGAGGTGTAACATTCCCAGGAGTAGATGTCATTG
TCGTTCAAGCCAATCACTACTTATACACCTCATCTAGTCTTGTGCAAATTTCAGGTCGCGTCGGAAGAAGTATGGACCGC
CCGACGGGCTTGCTTCTGTTTTTTCATGAAGGAAGTACGCGATCAATTGAAAAGGCAATTGCAGAAATTAAACAAATGAA
TAAGGAGGCAGGTTATGTCTAG

Domains

Predicted by InterproScan.

• Helicase conserved C-terminal domain (Helicase_C) (290-396)

• Type III restriction enzyme, res subunit (ResIII) (95-168)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comFA/cflA	Streptococcus pneumoniae Rx1	65.34	98.614	0.644
comFA/cflA	Streptococcus pneumoniae D39	65.34	98.614	0.644
comFA/cflA	Streptococcus pneumoniae R6	65.34	98.614	0.644
comFA/cflA	Streptococcus pneumoniae TIGR4	65.34	98.614	0.644
comFA/cflA	Streptococcus mitis NCTC 12261	65.412	98.152	0.642
comFA/cflA	Streptococcus mitis SK321	65.176	98.152	0.64
comFA	Lactococcus lactis subsp. cremoris KW2	51.508	91.917	0.473
comFA	Latilactobacillus sakei subsp. sakei 23K	37.063	99.076	0.367