Detailed information NTG0084187

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: JN178_RS14980
• Genome accession: NZ_AP024235
• Coordinates: 3378657..3379568 (+)
• Length: 303 a.a.
• NCBI ID: WP_202262235.1
• Uniprot ID: A0A7R7GG36
• Organism: Alteromonas sp. KC3
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 3373657..3384568

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JN178_RS14955 (KUC3_29520)	ampD	3374388..3374957 (-)	570	WP_202262232.1	1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD	-
JN178_RS14960 (KUC3_29530)	-	3375090..3375608 (+)	519	WP_202262233.1	TIGR02281 family clan AA aspartic protease	-
JN178_RS14965 (KUC3_29540)	nadC	3375629..3376483 (+)	855	WP_202266089.1	carboxylating nicotinate-nucleotide diphosphorylase	-
JN178_RS14970 (KUC3_29550)	-	3376877..3377305 (+)	429	WP_269752164.1	prepilin-type N-terminal cleavage/methylation domain-containing protein	-
JN178_RS14975 (KUC3_29560)	pilC	3377398..3378609 (+)	1212	WP_202262234.1	type II secretion system F family protein	Machinery gene
JN178_RS14980 (KUC3_29570)	pilD	3378657..3379568 (+)	912	WP_202262235.1	A24 family peptidase	Machinery gene
JN178_RS14985 (KUC3_29580)	coaE	3379611..3380222 (+)	612	WP_202262236.1	dephospho-CoA kinase	-
JN178_RS14990 (KUC3_29590)	zapD	3380466..3381218 (+)	753	WP_202262237.1	cell division protein ZapD	-
JN178_RS14995 (KUC3_29600)	yacG	3381271..3381498 (+)	228	WP_159626843.1	DNA gyrase inhibitor YacG	-
JN178_RS15000 (KUC3_29610)	-	3381572..3381994 (-)	423	WP_202262238.1	MerR family transcriptional regulator	-
JN178_RS15005 (KUC3_29620)	-	3382081..3383319 (+)	1239	WP_202262239.1	NADH:flavin oxidoreductase/NADH oxidase family protein	-
JN178_RS15010 (KUC3_29630)	-	3383413..3384285 (+)	873	WP_159626840.1	aspartoacylase	-

Sequence

Protein

• Length: 303 a.a.
• Molecular weight: 33712.92 Da
• Isoelectric Point: 7.2939

>NTDB_id=84187 JN178_RS14980 WP_202262235.1 3378657..3379568(+) (pilD) [Alteromonas sp. KC3]
MDVSFAQHLVTLHQVAPLFFYSLIFIVSLMVGSFLNVVIYRLPIMMERSWQREYNDYFAEQGDERVTTAQIDSQEAPFNL
VKPDSTCPSCGHKIRAWENIPVISYLFLKGKCSKCKTGISPRYPAVELFTALVCTFAAYHFGPTPQALWAVLFTYALISL
LFIDLDKMLLPDQLTLPLLWLGLILSTHNVFVTPTEAIIGAAAGYLSLWSVYWLFKLVTGKEGMGYGDFKLLAALGAFTG
WQGLPVIILLSSFVGAVVGIVIMIVQKQGKSLAIPFGPYLAVAGWLTLLYKTDIITAYLNMVL

Nucleotide

• Length: 912 bp

>NTDB_id=84187 JN178_RS14980 WP_202262235.1 3378657..3379568(+) (pilD) [Alteromonas sp. KC3]
ATGGATGTTTCATTCGCTCAGCACTTGGTTACATTACACCAGGTAGCGCCACTATTTTTCTATTCACTTATCTTTATTGT
TAGCTTGATGGTTGGCAGCTTTTTAAATGTTGTAATCTACCGGTTACCAATCATGATGGAGCGTAGTTGGCAGCGTGAAT
ACAATGACTATTTTGCCGAACAAGGTGACGAGCGAGTCACAACGGCCCAAATAGATAGCCAAGAAGCTCCCTTTAACCTT
GTAAAACCAGACAGTACATGTCCGTCGTGTGGACATAAAATTCGCGCTTGGGAAAACATTCCTGTCATAAGTTACCTTTT
CCTGAAAGGGAAGTGTTCGAAATGCAAAACCGGAATTTCACCACGTTATCCGGCAGTTGAGTTATTCACGGCTTTGGTAT
GCACGTTTGCTGCGTACCATTTTGGCCCCACACCACAAGCCTTATGGGCGGTCCTATTCACCTATGCACTTATATCGTTA
CTGTTTATTGATTTAGACAAAATGCTGTTACCCGATCAACTCACGCTTCCACTGCTTTGGTTGGGTTTAATACTCAGTAC
GCATAACGTTTTCGTCACTCCAACAGAGGCAATCATTGGTGCAGCTGCAGGCTACCTTAGTTTATGGTCTGTATATTGGT
TGTTTAAACTTGTTACCGGCAAAGAAGGTATGGGCTATGGCGACTTTAAATTATTAGCCGCTTTAGGGGCTTTTACGGGC
TGGCAAGGCTTGCCCGTTATTATCTTGCTTTCGTCTTTTGTGGGTGCGGTGGTTGGCATTGTAATTATGATTGTACAGAA
ACAAGGAAAGTCTCTGGCCATTCCATTTGGCCCTTACCTCGCGGTAGCTGGATGGTTAACCTTACTGTATAAAACCGATA
TCATTACCGCTTACTTAAATATGGTGTTGTAG

Domains

Predicted by InterproScan.

• Type IV leader peptidase family (Peptidase_A24) (153-260)

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (26-141)

3D structure

• AlphaFold DB: A0A7R7GG36

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Vibrio campbellii strain DS40M4	52.921	96.04	0.508
pilD	Vibrio cholerae strain A1552	53.684	94.059	0.505
pilD	Acinetobacter baumannii D1279779	49.11	92.739	0.455
pilD	Acinetobacter nosocomialis M2	48.754	92.739	0.452
pilD	Neisseria gonorrhoeae MS11	48.881	88.449	0.432