Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   VVB72_RS02740 Genome accession   NZ_CP142589
Coordinates   529725..531803 (+) Length   692 a.a.
NCBI ID   WP_039114709.1    Uniprot ID   -
Organism   Lactococcus lactis subsp. lactis strain C20     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 524725..536803
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VVB72_RS02720 (VVB72_02720) - 526671..527141 (-) 471 WP_003130820.1 Rrf2 family transcriptional regulator -
  VVB72_RS02725 (VVB72_02725) gap 527314..528327 (+) 1014 WP_039114704.1 type I glyceraldehyde-3-phosphate dehydrogenase -
  VVB72_RS02730 (VVB72_02730) def 528470..529105 (-) 636 WP_003130816.1 peptide deformylase -
  VVB72_RS02735 (VVB72_02735) - 529253..529714 (+) 462 WP_310574176.1 RNA pyrophosphohydrolase -
  VVB72_RS02740 (VVB72_02740) uvrB 529725..531803 (+) 2079 WP_039114709.1 excinuclease ABC subunit UvrB Machinery gene
  VVB72_RS02745 (VVB72_02745) - 531999..532808 (+) 810 WP_080756652.1 ABC transporter substrate-binding protein -
  VVB72_RS02750 (VVB72_02750) - 532823..533941 (+) 1119 WP_033899697.1 M20 family metallopeptidase -
  VVB72_RS02755 (VVB72_02755) fabZ 534009..534464 (-) 456 WP_003130498.1 3-hydroxyacyl-ACP dehydratase FabZ -
  VVB72_RS02760 (VVB72_02760) fabI 534740..535492 (+) 753 WP_039114714.1 enoyl-ACP reductase FabI -

Sequence

Protein


Download         Length: 692 a.a.        Molecular weight: 79121.44 Da        Isoelectric Point: 4.5652

>NTDB_id=841202 VVB72_RS02740 WP_039114709.1 529725..531803(+) (uvrB) [Lactococcus lactis subsp. lactis strain C20]
MAIERITDNKFELVSKYEPAGDQGEAIAELVDNIENGEKAQILRGATGTGKTYTMSQVIARTGKPTLVMAHNKTLAGQLY
SEFKEFFPNNAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEY
QDSVVSLRPGQEISRDQLLNDLVGIQFERNDIDFQRGCFRVRGDVVEVFPASRDEHAFRVEFFGDEIDRIREIEVLTGQV
LGEVDHLAIFPATHFMTNDDRMEESIAKIEAELEEQLKVFRSEGKLLEAQRLEQRTNYDIEMLREMGYCNGVENYSRHMD
GREEGEPPYTLLDFFPDDFMIMIDESHMTMGQVKGMYNGDRARKEMLCNYGFRLPSALDNRPLKREEFESHVHQMVYVSA
TPGDYEMEQTDTIVEQIIRPTGLLDPVVEVRPMMGQIDDLVGEIHKRAEKNERVFVTTLTKKMSEDLTAYFKEMGIKVKY
MHSDIKTLERTEIIRDLRLGVFDVLVGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVILYSD
MAKALDENDPADKEILDSGYYTEYEGQKYKITRSMKHAMDETARRREIQMAYNEEHGITPQTIKKEIRDLIAITKKTDSG
EIEEVDASAMTKKERKALVKKLEKEMQQAASALDFEGAAQLRDMVLELRAMD

Nucleotide


Download         Length: 2079 bp        

>NTDB_id=841202 VVB72_RS02740 WP_039114709.1 529725..531803(+) (uvrB) [Lactococcus lactis subsp. lactis strain C20]
ATGGCTATAGAAAGAATAACAGATAATAAATTTGAACTTGTTTCAAAATATGAGCCAGCCGGTGACCAAGGTGAGGCGAT
TGCTGAGTTAGTAGATAATATTGAGAATGGGGAAAAAGCTCAAATTTTACGTGGAGCAACAGGAACAGGGAAAACTTACA
CCATGAGTCAAGTGATTGCACGGACAGGTAAACCTACTCTTGTTATGGCTCATAATAAAACACTGGCTGGTCAATTATAC
AGTGAATTTAAAGAGTTTTTCCCAAATAATGCAGTCGAGTATTTCGTATCCTACTATGATTATTATCAACCCGAAGCCTA
TGTGCCAAGTTCTGACACCTATATTGAAAAAGACAGTTCGGTCAATGATGAAATTGATAAATTGCGTCATAGTGCGACCT
CAAGCTTATTGGAACGTAATGATGTGATTGTTGTGGCCTCAGTTTCTTGTATTTATGGTTTGGGTTCACCCAAAGAGTAT
CAAGATTCGGTGGTTTCATTGCGCCCAGGTCAAGAAATTTCTCGTGACCAACTTTTAAATGATTTGGTAGGAATTCAATT
TGAGCGAAATGATATTGACTTTCAACGGGGCTGTTTCCGAGTTCGTGGGGATGTTGTAGAAGTTTTTCCAGCCTCTCGTG
ATGAACATGCCTTTCGTGTTGAATTTTTCGGTGATGAAATTGACCGTATCCGTGAAATTGAAGTTTTGACCGGACAAGTT
TTAGGTGAAGTAGACCATTTGGCAATTTTTCCAGCGACACATTTCATGACAAATGATGACCGTATGGAAGAATCAATTGC
CAAGATAGAAGCAGAATTAGAAGAACAACTAAAAGTTTTCCGCTCAGAAGGAAAACTTCTTGAGGCTCAACGTTTAGAAC
AAAGAACCAACTACGATATCGAAATGCTCCGTGAAATGGGTTATTGTAATGGGGTTGAAAACTATTCACGTCATATGGAT
GGGCGCGAGGAAGGCGAACCTCCGTATACTTTGCTTGATTTCTTTCCTGATGATTTCATGATTATGATTGATGAATCACA
CATGACAATGGGGCAAGTAAAAGGAATGTATAACGGTGACAGAGCCCGTAAAGAAATGCTTTGTAATTATGGATTCCGCC
TGCCTTCAGCCCTCGATAACCGTCCTTTAAAAAGAGAAGAATTTGAAAGTCATGTGCATCAAATGGTTTATGTTTCAGCA
ACCCCTGGGGATTATGAGATGGAGCAGACCGATACCATTGTTGAACAAATTATTCGTCCAACAGGTCTATTAGATCCTGT
CGTAGAAGTTCGACCAATGATGGGACAAATCGATGATTTAGTTGGTGAAATTCATAAACGAGCTGAGAAAAACGAACGAG
TATTCGTCACGACTTTGACTAAAAAGATGTCAGAAGATTTGACTGCCTATTTCAAGGAAATGGGGATAAAAGTTAAATAT
ATGCACTCGGATATCAAAACATTAGAACGAACCGAAATTATTCGGGATTTGCGTTTAGGAGTCTTTGATGTTCTGGTGGG
AATTAATTTGCTTCGTGAAGGGATAGACGTGCCAGAAGTTTCTTTAGTAGCAATTTTGGATGCTGATAAAGAAGGATTTT
TACGTAATGAGCGTGGCTTGATTCAGACCATTGGTCGTGCAGCACGTAATAGTGAAGGTCATGTTATTCTTTATTCTGAT
ATGGCTAAAGCCCTTGATGAAAATGATCCTGCGGATAAAGAAATCTTAGACAGTGGTTATTATACAGAATACGAGGGTCA
AAAGTATAAAATAACGCGTTCAATGAAACATGCGATGGATGAAACGGCCCGCCGGCGTGAAATTCAAATGGCTTATAATG
AAGAACATGGAATCACACCTCAAACGATCAAAAAAGAAATTCGTGATTTGATTGCCATTACTAAGAAAACTGATTCTGGT
GAGATTGAAGAAGTCGATGCAAGTGCGATGACTAAGAAAGAACGTAAAGCATTAGTCAAAAAACTTGAAAAAGAAATGCA
ACAAGCGGCTAGCGCCCTCGACTTTGAAGGAGCTGCTCAGTTACGTGATATGGTATTAGAATTACGTGCAATGGATTGA

Domains

Predicted by InterProScan.

UvrB interaction domain (UvrB_inter)

(165-255)

Helicase conserved C-terminal domain (Helicase_C)

(441-550)

Type III restriction enzyme, res subunit (ResIII)

(19-144)

Ultra-violet resistance protein B (UvrB)

(590-628)

UvrB/uvrC motif (UVR)

(657-690)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

81.884

99.711

0.816
  uvrB Streptococcus pneumoniae D39

81.884

99.711

0.816
  uvrB Streptococcus pneumoniae TIGR4

81.739

99.711

0.815