Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   VVB72_RS02105 Genome accession   NZ_CP142589
Coordinates   418486..419928 (-) Length   480 a.a.
NCBI ID   WP_052230896.1    Uniprot ID   -
Organism   Lactococcus lactis subsp. lactis strain C20     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 413486..424928
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VVB72_RS02080 (VVB72_02080) nox 413520..414860 (+) 1341 WP_039114608.1 H2O-forming NADH oxidase -
  VVB72_RS02085 (VVB72_02085) - 414950..415339 (+) 390 WP_010905314.1 single-stranded DNA-binding protein -
  VVB72_RS02090 (VVB72_02090) groES 415459..415743 (+) 285 WP_003131589.1 co-chaperone GroES -
  VVB72_RS02095 (VVB72_02095) groL 415831..417459 (+) 1629 WP_003131585.1 chaperonin GroEL -
  VVB72_RS02100 (VVB72_02100) vicX 417505..418317 (-) 813 WP_039114610.1 MBL fold metallo-hydrolase Regulator
  VVB72_RS02105 (VVB72_02105) vicK 418486..419928 (-) 1443 WP_052230896.1 sensor histidine kinase Regulator
  VVB72_RS02110 (VVB72_02110) yycF 419921..420622 (-) 702 WP_003131580.1 response regulator YycF -
  VVB72_RS02115 (VVB72_02115) tmk 420800..421435 (+) 636 WP_012897230.1 dTMP kinase -
  VVB72_RS02120 (VVB72_02120) - 421568..422428 (+) 861 WP_003131573.1 DNA polymerase III subunit delta' -
  VVB72_RS02125 (VVB72_02125) yaaT 422480..423262 (+) 783 WP_039114615.1 stage 0 sporulation family protein Regulator
  VVB72_RS02130 (VVB72_02130) yabA 423255..423581 (+) 327 WP_003131570.1 DNA replication initiation control protein YabA -
  VVB72_RS02135 (VVB72_02135) rsmI 423581..424456 (+) 876 WP_039114617.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
  VVB72_RS02140 (VVB72_02140) - 424533..424724 (-) 192 WP_012897234.1 hypothetical protein -

Sequence

Protein


Download         Length: 480 a.a.        Molecular weight: 54663.14 Da        Isoelectric Point: 4.5889

>NTDB_id=841195 VVB72_RS02105 WP_052230896.1 418486..419928(-) (vicK) [Lactococcus lactis subsp. lactis strain C20]
MIKFFNSMIFKGVVAHLLLFVILFMSSFDYNFAHLSTFIGYYLFSLVFVLVFLNQQHRMIVNVSKQMNDIKNGYLNRDKI
PKGTSEINELYDEILKLGEDIIRTQNNLENQRNQLDSILAYMVDGVIATDRRGNIIMANKSALHYLNTDNDLLMQKNIVE
VLKIADQYNFYDLLEKEPEITIETHDAGNESISLHIKFALFRRESGFISGIIAVLHDMTEQDKAERERRLFVSNVSHELR
TPLTSVKAYLEALEDGAIEDKETASSFINVSLTETNRMIRMISDLLTLSRMDQDRIVLNKEMINLIAFLDYQINRLDQIL
ETESNDLISSNFTLVRKYSEQPIWVEIDTDKIAQVIDNIIGNAIKYSPKGGTITISVEKRESDVLISISDQGMGIPKSDL
LKIFDRFYRVDNASRNSKVGGTGLGLSIVHDIVKIHGGTIFASSEGEGKGTTFSFTLPYSLEAADDWDDGTDEFEFEDNE

Nucleotide


Download         Length: 1443 bp        

>NTDB_id=841195 VVB72_RS02105 WP_052230896.1 418486..419928(-) (vicK) [Lactococcus lactis subsp. lactis strain C20]
ATGATTAAATTTTTTAATTCAATGATTTTTAAAGGAGTAGTTGCACACCTACTTCTTTTTGTCATCCTTTTTATGAGCAG
TTTTGATTACAATTTTGCTCATTTAAGTACTTTTATTGGTTATTACTTATTTTCACTCGTCTTTGTTTTAGTCTTTCTCA
ATCAGCAACATCGCATGATTGTGAATGTTTCTAAACAGATGAATGACATAAAAAATGGCTATTTAAATCGGGATAAAATC
CCAAAAGGGACGAGTGAAATCAATGAATTATATGATGAAATTTTAAAACTTGGTGAAGATATTATTCGCACGCAGAACAA
TCTTGAAAATCAGCGTAATCAATTAGATAGTATTCTCGCATATATGGTTGATGGCGTCATTGCCACCGATCGTCGTGGAA
ATATTATTATGGCCAATAAATCAGCTTTGCATTATTTGAATACAGATAATGATCTCTTGATGCAAAAAAATATTGTTGAA
GTTTTAAAAATTGCTGACCAATATAATTTTTATGATTTATTAGAAAAAGAACCTGAAATAACTATTGAGACACATGATGC
TGGGAATGAATCCATTTCGCTCCACATTAAATTTGCCCTCTTTCGTCGTGAATCTGGTTTCATCTCAGGAATTATTGCCG
TCTTACATGATATGACTGAACAAGACAAGGCCGAACGAGAGCGCCGTCTCTTTGTTTCCAATGTTTCTCATGAACTCCGA
ACTCCGCTCACCTCAGTAAAAGCCTACTTGGAAGCACTAGAAGACGGAGCCATTGAGGATAAAGAAACAGCTTCATCCTT
TATTAATGTTTCACTTACTGAAACTAATCGGATGATTCGAATGATTTCCGACCTTTTGACTTTATCAAGAATGGATCAAG
ACCGAATCGTTCTTAATAAAGAAATGATTAATTTAATTGCCTTCTTAGACTATCAAATTAACCGTTTAGACCAAATTTTA
GAAACCGAATCAAACGATTTAATCTCTTCTAATTTCACTCTAGTCAGAAAATACTCTGAACAGCCCATCTGGGTCGAAAT
TGATACCGATAAAATTGCTCAAGTCATTGACAATATCATCGGAAATGCAATTAAGTATTCACCTAAAGGTGGAACTATTA
CAATTTCCGTTGAAAAACGTGAAAGTGACGTTCTAATCTCCATCAGTGACCAAGGAATGGGAATTCCAAAATCTGATTTA
CTTAAGATTTTTGACCGTTTCTACCGAGTTGATAATGCTTCAAGAAATTCAAAAGTTGGGGGGACAGGTTTAGGCCTTTC
CATTGTCCATGATATTGTTAAAATACATGGCGGAACAATTTTTGCAAGCTCCGAAGGAGAAGGAAAAGGAACGACCTTTA
GTTTCACTCTTCCATATTCTTTAGAAGCCGCAGATGACTGGGATGATGGCACTGATGAGTTTGAATTTGAGGATAATGAA
TAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(348-459)

PAS domain (PAS_9)

(124-220)

His Kinase A (phospho-acceptor) domain (HisKA)

(228-293)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

51.559

86.875

0.448
  micB Streptococcus pneumoniae Cp1015

47.748

92.5

0.442