Detailed information NTG0840892

Bioinformatically predicted

Overview

• Name: uvrB
• Type: Machinery gene
• Locus tag: VKP34_RS05445
• Genome accession: NZ_CP142358
• Coordinates: 1058533..1060524 (-)
• Length: 663 a.a.
• NCBI ID: WP_002984194.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain 6702-99
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1053533..1065524

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VKP34_RS05420 (VKP34_05420)	dltD	1053823..1055073 (-)	1251	WP_002984219.1	D-alanyl-lipoteichoic acid biosynthesis protein DltD	-
VKP34_RS05425 (VKP34_05425)	dltC	1055066..1055305 (-)	240	WP_002984216.1	D-alanine--poly(phosphoribitol) ligase subunit DltC	-
VKP34_RS05430 (VKP34_05430)	dltB	1055323..1056579 (-)	1257	WP_002994626.1	D-alanyl-lipoteichoic acid biosynthesis protein DltB	-
VKP34_RS05435 (VKP34_05435)	dltA	1056576..1058114 (-)	1539	WP_020837260.1	D-alanine--poly(phosphoribitol) ligase subunit DltA	-
VKP34_RS05440 (VKP34_05440)	-	1058126..1058269 (-)	144	WP_002984200.1	teichoic acid D-Ala incorporation-associated protein DltX	-
VKP34_RS05445 (VKP34_05445)	uvrB	1058533..1060524 (-)	1992	WP_002984194.1	excinuclease ABC subunit UvrB	Machinery gene
VKP34_RS05450 (VKP34_05450)	-	1060717..1062891 (+)	2175	WP_002984191.1	ABC transporter substrate-binding protein/permease	-
VKP34_RS05455 (VKP34_05455)	-	1062891..1063631 (+)	741	WP_002984187.1	amino acid ABC transporter ATP-binding protein	-
VKP34_RS05460 (VKP34_05460)	-	1063779..1063931 (-)	153	WP_002992847.1	hypothetical protein	-
VKP34_RS05465 (VKP34_05465)	-	1063928..1065307 (-)	1380	WP_002992849.1	PTS sugar transporter subunit IIC	-

Sequence

Protein

• Length: 663 a.a.
• Molecular weight: 75654.68 Da
• Isoelectric Point: 4.6420

>NTDB_id=840892 VKP34_RS05445 WP_002984194.1 1058533..1060524(-) (uvrB) [Streptococcus pyogenes strain 6702-99]
MIDKRDDKPFKLKSKYKPSGDQPQAIESLVDNIEGGEKAQILLGATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYG
EFKEFFPDNAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEYA
DSAVSLRPGQEISRDTLLNQLVDIQFERNDIDFQRGCFRVRGDVVEVFPASRDEHAFRVEFFGDEIDRICEIESLTGKTI
GEVDHLVLFPATHFVTNDEHMEQSIAKIQAELAEQLQLFESEGKLLEAQRLRQRTEYDIEMLREMGYTSGVENYSRHMDG
RSPGEPPYTLLDFFPEDFLIMIDESHMTMGQIKGMYNGDQARKQMLVDYGFRLPSALDNRPLRREEFESHVHQIVYVSAT
PGEYEMSQTNTIIEQIIRPTGLLDPEIDVRSSMGQMDDLLGEINQRVARDERTFITTLTKKMAEDLTDYLKEMGVKVKYM
HSDIKTLERTEIIRDLRLGVFDVLIGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNVDGHVIMYADK
MTDSMQRAIDETARRREIQIAYNKAHGIVPQTIKKDIRGLISISKTSHNDISKEEMDYESMSRGERKEAINALQKQMQEA
AELLDFELAAQMRDLILELKLMD

Nucleotide

• Length: 1992 bp

>NTDB_id=840892 VKP34_RS05445 WP_002984194.1 1058533..1060524(-) (uvrB) [Streptococcus pyogenes strain 6702-99]
ATGATTGATAAACGTGATGATAAACCATTTAAACTAAAATCAAAGTATAAACCGTCTGGTGATCAGCCACAAGCTATTGA
AAGCCTAGTTGATAATATCGAGGGCGGAGAAAAAGCTCAGATTCTCCTAGGTGCTACAGGAACGGGAAAAACATACACCA
TGAGCCAAGTAATTAGTAAAGTAAATAAACCTACCTTAGTGATAGCTCACAATAAAACCTTAGCAGGACAATTATATGGT
GAATTTAAAGAATTTTTTCCAGACAATGCTGTGGAATACTTTGTTTCCTATTATGATTACTACCAACCTGAAGCATATGT
CCCATCAAGCGACACCTATATCGAAAAAGATAGTTCAGTCAATGATGAAATCGATAAACTTCGCCATTCAGCCACCTCTT
CTTTACTTGAGCGTAACGATGTCATAGTGGTAGCTTCTGTATCTTGTATTTATGGACTAGGTTCGCCAAAAGAGTACGCA
GATTCAGCAGTCAGCCTACGTCCAGGTCAGGAGATATCACGTGACACTTTGCTAAATCAATTAGTAGATATTCAATTTGA
GCGTAATGATATTGATTTTCAACGCGGCTGTTTTCGTGTACGTGGCGATGTTGTTGAGGTCTTTCCAGCATCCAGGGATG
AACATGCTTTTCGGGTGGAATTTTTCGGGGATGAGATTGACCGTATATGTGAAATCGAAAGTTTAACTGGGAAAACTATT
GGAGAAGTTGACCATTTGGTTTTATTTCCAGCTACTCACTTTGTAACAAATGATGAGCATATGGAGCAATCAATAGCCAA
AATTCAAGCAGAGTTAGCAGAGCAGTTACAGTTATTTGAATCTGAAGGTAAACTACTAGAAGCACAGCGATTACGCCAAA
GAACGGAATATGATATTGAAATGTTACGTGAAATGGGCTATACTAGCGGAGTCGAAAACTATTCCCGTCATATGGATGGC
AGGTCACCAGGAGAACCTCCTTATACCTTGTTAGATTTCTTCCCAGAAGATTTTTTAATTATGATTGATGAAAGTCACAT
GACAATGGGACAAATCAAAGGCATGTATAATGGTGACCAAGCCAGAAAACAAATGCTAGTTGACTATGGTTTTCGATTGC
CATCAGCTCTTGATAATCGTCCCTTAAGACGCGAGGAATTTGAAAGTCATGTGCACCAAATTGTCTATGTTTCAGCAACG
CCTGGTGAATACGAAATGTCACAGACTAATACAATTATTGAGCAAATTATTCGTCCGACTGGACTACTTGATCCTGAAAT
TGATGTAAGGTCAAGTATGGGGCAAATGGATGATTTGTTGGGAGAAATTAACCAGCGCGTAGCGCGCGATGAACGGACGT
TCATCACAACCTTAACTAAAAAAATGGCAGAAGATTTGACTGATTATCTAAAAGAGATGGGTGTCAAGGTCAAGTATATG
CACAGTGATATTAAAACCTTAGAGCGAACAGAAATTATTCGTGATTTACGACTTGGTGTTTTTGATGTCTTGATTGGAAT
CAATCTGCTCCGTGAAGGGATTGATGTGCCAGAAGTTAGTCTTGTAGCCATTTTGGATGCTGATAAAGAGGGTTTCCTCC
GTAATGAACGCGGCTTGATTCAGACCATCGGTAGAGCAGCTCGAAACGTAGATGGTCATGTCATTATGTATGCGGACAAG
ATGACAGATTCTATGCAGCGAGCTATTGACGAAACGGCTCGTCGTCGTGAGATTCAAATAGCATATAACAAAGCGCACGG
CATCGTTCCACAAACTATAAAAAAAGACATCAGAGGCCTTATTAGTATAAGTAAAACAAGCCACAATGATATATCAAAAG
AAGAGATGGATTATGAAAGTATGTCAAGAGGAGAACGAAAAGAAGCGATCAATGCTCTGCAAAAACAAATGCAAGAGGCA
GCTGAATTACTTGATTTCGAATTGGCAGCTCAAATGCGAGACTTGATTTTAGAACTTAAATTAATGGACTAG

Domains

Predicted by InterProScan.

• Ultra-violet resistance protein B (UvrB) (556-598)

• UvrB interaction domain (UvrB_inter) (164-254)

• Helicase conserved C-terminal domain (Helicase_C) (443-548)

• UvrB/uvrC motif (UVR) (627-660)

• Type III restriction enzyme, res subunit (ResIII) (17-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrB	Streptococcus pneumoniae R6	84.917	100	0.849
uvrB	Streptococcus pneumoniae D39	84.917	100	0.849
uvrB	Streptococcus pneumoniae TIGR4	84.766	100	0.848