NTDB

Overview

Name	ruvA	Type	Machinery gene
Locus tag	VKP36_RS08520	Genome accession	NZ_CP142357
Coordinates	1715907..1716503 (-)	Length	198 a.a.
NCBI ID	WP_002992186.1	Uniprot ID	P0DF49
Organism	Streptococcus pyogenes strain AW-534
Function	homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1710907..1721503

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VKP36_RS08485 (VKP36_08485)	-	1710966..1711271 (-)	306	WP_002982199.1	DUF1292 domain-containing protein	-
VKP36_RS08490 (VKP36_08490)	ruvX	1711283..1711702 (-)	420	WP_002982196.1	Holliday junction resolvase RuvX	-
VKP36_RS08495 (VKP36_08495)	-	1711699..1711968 (-)	270	WP_002982194.1	IreB family regulatory phosphoprotein	-
VKP36_RS08500 (VKP36_08500)	spx	1712083..1712481 (-)	399	WP_002982188.1	transcriptional regulator Spx	-
VKP36_RS08505 (VKP36_08505)	recA	1712772..1713908 (-)	1137	WP_023612663.1	recombinase RecA	Machinery gene
VKP36_RS08510 (VKP36_08510)	cinA	1713997..1715268 (-)	1272	WP_032465305.1	competence/damage-inducible protein A	Machinery gene
VKP36_RS08515 (VKP36_08515)	-	1715337..1715897 (-)	561	WP_010922755.1	DNA-3-methyladenine glycosylase I	-
VKP36_RS08520 (VKP36_08520)	ruvA	1715907..1716503 (-)	597	WP_002992186.1	Holliday junction branch migration protein RuvA	Machinery gene
VKP36_RS08525 (VKP36_08525)	-	1716505..1717725 (-)	1221	WP_014407934.1	MDR family MFS transporter	-
VKP36_RS08530 (VKP36_08530)	hexB	1717736..1719718 (-)	1983	WP_010922757.1	DNA mismatch repair endonuclease MutL	Machinery gene
VKP36_RS08535 (VKP36_08535)	-	1719813..1720964 (-)	1152	WP_003058754.1	tyrosine-type recombinase/integrase	-
VKP36_RS08540 (VKP36_08540)	-	1721213..1721356 (+)	144	WP_326624817.1	putative holin-like toxin	-

Sequence

Protein

Download Length: 198 a.a. Molecular weight: 21879.26 Da Isoelectric Point: 6.8838

                                >NTDB_id=840832 VKP36_RS08520 WP_002992186.1 1715907..1716503(-) (ruvA) [Streptococcus pyogenes strain AW-534]

MYDYIKGQLTKITAKYIVVEANGLGYMINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGI

GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGHTKARSNKAGNTQLDEAIEAL

LALGYKAKELKKIRAFFEGTSETAEQYIKSALKLLMKG

Nucleotide

Download Length: 597 bp

                                >NTDB_id=840832 VKP36_RS08520 WP_002992186.1 1715907..1716503(-) (ruvA) [Streptococcus pyogenes strain AW-534]

ATGTACGATTATATTAAAGGTCAATTGACCAAAATTACGGCAAAATACATTGTCGTTGAAGCTAATGGATTGGGCTACAT

GATTAATGTTGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAATTGGTAACCATTTATCTGCATCAAGTGATTCGTG

AGGATGCTCACCTGTTGTTTGGGTTTCACACGGAAGATGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCAGGTATT

GGTCCGACAACAGCTCTTGCTATTGTGGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA

GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGCTGGCAAATTTGTGGAGG

CTCCACAAGAGACTGGTCATACCAAAGCGCGCAGCAATAAAGCAGGCAATACTCAACTGGACGAAGCGATTGAAGCCCTC

CTTGCTCTCGGTTATAAAGCAAAAGAGCTGAAAAAAATTCGTGCCTTCTTTGAGGGGACCTCTGAGACGGCAGAGCAATA

CATCAAATCAGCATTGAAACTGTTAATGAAAGGGTAG

Domains

Predicted by InterProScan.

RuvA N terminal domain (RuvA_N)

(1-61)

Helix-hairpin-helix domain (HHH_5)

(71-127)

RuvA, C-terminal domain (RuvA_C)

(152-196)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	P0DF49

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
ruvA	Streptococcus pneumoniae TIGR4	65.99	99.495	0.657
ruvA	Streptococcus pneumoniae R6	65.99	99.495	0.657
ruvA	Streptococcus pneumoniae D39	65.99	99.495	0.657
ruvA	Bacillus subtilis subsp. subtilis str. 168	40.887	100	0.419

Detailed information NTG0840832