Detailed information    

insolico Bioinformatically predicted

Overview

Name   scnR   Type   Regulator
Locus tag   VKP40_RS06765 Genome accession   NZ_CP142355
Coordinates   1349422..1350120 (+) Length   232 a.a.
NCBI ID   WP_085613747.1    Uniprot ID   O31050
Organism   Streptococcus pyogenes strain A946     
Function   regulate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1344422..1355120
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VKP40_RS06745 (VKP40_06745) - 1345724..1348507 (-) 2784 WP_109821249.1 type 2 lanthipeptide synthetase LanM family protein -
  VKP40_RS06750 (VKP40_06750) - 1348528..1348683 (-) 156 WP_023612118.1 lacticin 481 family lantibiotic -
  VKP40_RS06755 (VKP40_06755) - 1348883..1349038 (-) 156 WP_085613746.1 lacticin 481 family lantibiotic -
  VKP40_RS06760 (VKP40_06760) - 1349069..1349224 (-) 156 WP_023612114.1 lacticin 481 family lantibiotic -
  VKP40_RS06765 (VKP40_06765) scnR 1349422..1350120 (+) 699 WP_085613747.1 response regulator transcription factor Regulator
  VKP40_RS06770 (VKP40_06770) - 1350138..1351499 (+) 1362 WP_109821250.1 sensor histidine kinase -
  VKP40_RS06775 (VKP40_06775) - 1351715..1352230 (-) 516 WP_136022160.1 helical hairpin domain-containing protein -
  VKP40_RS06780 (VKP40_06780) - 1352250..1353376 (+) 1127 WP_326675587.1 IS3 family transposase -
  VKP40_RS06785 (VKP40_06785) - 1353750..1354166 (-) 417 WP_326675589.1 hypothetical protein -
  VKP40_RS06790 (VKP40_06790) - 1354163..1354519 (-) 357 WP_011054285.1 hypothetical protein -
  VKP40_RS06795 (VKP40_06795) - 1354496..1354630 (-) 135 Protein_1286 portal protein -
  VKP40_RS09120 - 1354824..1354955 (-) 132 WP_011106853.1 hypothetical protein -

Sequence

Protein


Download         Length: 232 a.a.        Molecular weight: 26246.39 Da        Isoelectric Point: 6.1274

>NTDB_id=840629 VKP40_RS06765 WP_085613747.1 1349422..1350120(+) (scnR) [Streptococcus pyogenes strain A946]
MNFESQLLNKRILIVDDDVALSKSIKEVLISRDFKNISCAYSISEGIDIFSVSKIDLIILDVMLPDGEGHLLAKYIRKYS
DVPILFLTAKNNPDDEIRGLESGGDDYVTKPFLPKSLTYRIIALLRRAYKDESELIELTNCTIDLNNASVEKNGQHLSLT
PTEIQILRKLFSNKNYIASTESICDTVWGLESLGYEKSLMVHIRNIREKIEITPSKPNHLITVKGLGYKLVI

Nucleotide


Download         Length: 699 bp        

>NTDB_id=840629 VKP40_RS06765 WP_085613747.1 1349422..1350120(+) (scnR) [Streptococcus pyogenes strain A946]
ATGAATTTTGAGTCTCAATTATTGAATAAACGCATATTGATTGTCGACGATGATGTCGCACTTAGCAAATCAATTAAAGA
GGTACTTATCAGTCGGGATTTCAAGAATATCAGCTGTGCTTATAGTATAAGCGAAGGAATTGATATCTTCTCAGTTTCTA
AAATTGATCTCATTATTTTAGATGTTATGCTACCAGATGGAGAAGGGCACTTACTTGCAAAATACATTAGGAAATATTCA
GATGTGCCAATTCTCTTTTTAACAGCCAAAAACAATCCTGATGATGAAATTCGAGGACTTGAATCCGGAGGGGATGATTA
TGTTACGAAGCCATTTCTTCCCAAATCTTTAACATATCGTATTATTGCACTGTTGAGAAGGGCTTATAAAGATGAATCGG
AACTAATTGAGCTAACAAATTGTACCATAGACTTAAACAATGCAAGTGTTGAAAAAAATGGTCAACATTTGTCACTCACT
CCAACAGAAATACAAATCCTACGAAAATTATTTTCAAATAAAAATTATATTGCATCAACTGAATCGATTTGTGATACCGT
TTGGGGACTTGAGAGCCTTGGCTACGAAAAATCACTTATGGTACATATTCGTAATATCAGAGAAAAAATCGAGATAACTC
CATCTAAGCCAAATCATCTTATTACTGTAAAAGGGCTTGGTTATAAACTAGTTATATAA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-230)

Response regulator receiver domain (Response_reg)

(12-121)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB O31050

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  scnR Streptococcus mutans UA159

40.948

100

0.409
  vicR Streptococcus mutans UA159

38.528

99.569

0.384
  micA Streptococcus pneumoniae Cp1015

37.826

99.138

0.375