Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   VKP53_RS04065 Genome accession   NZ_CP142354
Coordinates   792342..794333 (+) Length   663 a.a.
NCBI ID   WP_002989569.1    Uniprot ID   P0DH39
Organism   Streptococcus pyogenes strain 6745-99     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 787342..799333
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VKP53_RS04045 (VKP53_04045) - 787559..788938 (+) 1380 WP_011528715.1 PTS sugar transporter subunit IIC -
  VKP53_RS04050 (VKP53_04050) - 788935..789087 (+) 153 WP_011528714.1 hypothetical protein -
  VKP53_RS04055 (VKP53_04055) - 789235..789975 (-) 741 WP_326675155.1 amino acid ABC transporter ATP-binding protein -
  VKP53_RS04060 (VKP53_04060) - 789975..792149 (-) 2175 WP_002984191.1 ABC transporter substrate-binding protein/permease -
  VKP53_RS04065 (VKP53_04065) uvrB 792342..794333 (+) 1992 WP_002989569.1 excinuclease ABC subunit UvrB Machinery gene
  VKP53_RS04070 (VKP53_04070) - 794597..794740 (+) 144 WP_002984200.1 teichoic acid D-Ala incorporation-associated protein DltX -
  VKP53_RS04075 (VKP53_04075) dltA 794752..796290 (+) 1539 WP_136075847.1 D-alanine--poly(phosphoribitol) ligase subunit DltA -
  VKP53_RS04080 (VKP53_04080) dltB 796287..797543 (+) 1257 WP_115230500.1 D-alanyl-lipoteichoic acid biosynthesis protein DltB -
  VKP53_RS04085 (VKP53_04085) dltC 797561..797800 (+) 240 WP_002984216.1 D-alanine--poly(phosphoribitol) ligase subunit DltC -
  VKP53_RS04090 (VKP53_04090) dltD 797793..799043 (+) 1251 WP_002984219.1 D-alanyl-lipoteichoic acid biosynthesis protein DltD -

Sequence

Protein


Download         Length: 663 a.a.        Molecular weight: 75664.72 Da        Isoelectric Point: 4.6420

>NTDB_id=840515 VKP53_RS04065 WP_002989569.1 792342..794333(+) (uvrB) [Streptococcus pyogenes strain 6745-99]
MIDKRDDKPFKLKSKYKPSGDQPQAIESLVDNIEGGEKAQILLGATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYG
EFKEFFPDNAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEYA
DSAVSLRPGQEISRDTLLNQLVDIQFERNDIDFQRGCFRVRGDVVEVFPASRDEHAFRVEFFGDEIDRICEIESLTGKTI
GEVDHLVLFPATHFVTNDEHMEQSIAKIQAELAEQLQLFESEGKLLEAQRLRQRTEYDIEMLREMGYTSGVENYSRHMDG
RSPGEPPYTLLDFFPEDFLIMIDESHMTMGQIKGMYNGDQARKQMLVDYGFRLPSALDNRPLRREEFESHVHQIVYVSAT
PGEYEMSQTNTIIEQIIRPTGLLDPEIDVRPSMGQMDDLLGEINQRVARDERTFITTLTKKMAEDLTDYLKEMGVKVKYM
HSDIKTLERTEIIRDLRLGVFDVLIGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNVDGHVIMYADK
MTDSMQRAIDETARRREIQIAYNKAHGIVPQTIKKDIRGLISISKTSHNDISKEEMDYESMSRGERKEAINALQKQMQEA
AELLDFELAAQMRDLILELKLMD

Nucleotide


Download         Length: 1992 bp        

>NTDB_id=840515 VKP53_RS04065 WP_002989569.1 792342..794333(+) (uvrB) [Streptococcus pyogenes strain 6745-99]
ATGATTGATAAACGTGATGATAAACCATTTAAACTAAAATCAAAGTATAAACCGTCTGGTGATCAGCCACAAGCTATTGA
AAGCCTAGTTGATAATATCGAGGGCGGAGAAAAAGCTCAGATTCTCCTAGGTGCTACAGGAACGGGAAAAACATACACCA
TGAGCCAAGTAATTAGTAAAGTAAATAAACCTACCTTAGTGATAGCTCACAATAAAACCTTAGCAGGACAATTATATGGT
GAATTTAAAGAATTTTTTCCAGACAATGCTGTGGAATATTTTGTTTCTTATTATGATTACTACCAACCTGAAGCATATGT
CCCATCAAGCGACACCTATATCGAAAAAGATAGTTCAGTCAATGATGAAATCGATAAACTTCGCCATTCAGCCACCTCTT
CTTTACTTGAGCGTAACGATGTCATAGTGGTAGCTTCTGTATCTTGTATTTATGGACTAGGTTCGCCAAAAGAGTACGCA
GATTCAGCAGTCAGCCTACGTCCAGGTCAGGAGATATCACGTGACACTTTGCTAAATCAATTAGTAGATATTCAATTTGA
GCGTAATGATATTGATTTTCAACGCGGCTGTTTTCGTGTACGTGGCGATGTTGTTGAGGTCTTTCCAGCATCCAGGGATG
AACATGCTTTTCGGGTGGAATTTTTCGGGGATGAGATTGACCGTATATGTGAAATCGAAAGTTTAACTGGGAAAACTATT
GGAGAAGTTGACCATTTGGTTTTATTTCCAGCTACTCACTTTGTAACAAATGATGAGCATATGGAGCAATCAATAGCCAA
AATTCAAGCAGAGTTAGCAGAGCAGTTACAGTTATTTGAATCTGAAGGTAAACTACTAGAAGCACAGCGATTACGCCAAA
GAACGGAATATGATATTGAAATGTTACGTGAAATGGGCTATACTAGCGGAGTCGAAAACTATTCCCGTCATATGGATGGC
AGGTCACCAGGAGAACCTCCTTATACCTTGTTAGATTTCTTCCCAGAAGATTTTTTAATTATGATTGATGAAAGTCACAT
GACAATGGGACAAATCAAAGGCATGTATAATGGTGACCAAGCCAGAAAACAAATGCTAGTTGACTATGGTTTTCGATTGC
CATCAGCTCTTGATAATCGTCCCTTAAGACGCGAGGAATTTGAAAGTCATGTGCACCAAATTGTCTATGTTTCAGCAACG
CCTGGTGAATACGAAATGTCACAGACTAATACAATTATTGAGCAAATTATTCGTCCGACTGGGCTACTTGATCCTGAAAT
TGATGTAAGGCCAAGTATGGGGCAAATGGATGATTTGTTGGGAGAAATTAACCAGCGCGTAGCGCGCGATGAACGGACGT
TCATCACAACCTTAACTAAAAAAATGGCAGAAGATTTGACTGATTATCTAAAAGAGATGGGTGTCAAGGTCAAGTATATG
CACAGTGATATTAAAACCTTAGAGCGGACAGAAATTATTCGTGATTTACGACTTGGTGTTTTTGATGTCTTGATTGGAAT
CAATCTGCTCCGTGAAGGGATTGATGTGCCAGAAGTTAGTCTTGTAGCCATTTTGGATGCTGATAAAGAGGGTTTCCTCC
GTAATGAACGCGGCTTGATTCAGACCATCGGTAGAGCAGCTCGAAACGTAGATGGTCATGTCATTATGTATGCGGACAAG
ATGACAGATTCTATGCAGCGGGCTATTGACGAAACGGCTCGTCGTCGTGAGATTCAAATAGCATATAACAAAGCGCACGG
CATCGTTCCACAAACTATAAAAAAAGACATCAGAGGCCTTATTAGTATAAGTAAAACAAGCCACAATGATATATCGAAAG
AAGAGATGGATTATGAAAGTATGTCAAGAGGAGAACGAAAAGAAGCGATCAATGCTCTGCAAAAACAAATGCAAGAGGCA
GCTGAATTACTTGATTTCGAATTGGCAGCTCAAATGCGAGACTTGATTTTAGAACTTAAATTAATGGACTAG

Domains

Predicted by InterProScan.

Ultra-violet resistance protein B (UvrB)

(556-598)

UvrB interaction domain (UvrB_inter)

(164-254)

Helicase conserved C-terminal domain (Helicase_C)

(443-548)

Type III restriction enzyme, res subunit (ResIII)

(17-142)

UvrB/uvrC motif (UVR)

(627-660)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0DH39

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

85.068

100

0.851
  uvrB Streptococcus pneumoniae D39

85.068

100

0.851
  uvrB Streptococcus pneumoniae TIGR4

84.917

100

0.849