Detailed information NTG0840419

Bioinformatically predicted

Overview

• Name: uvrB
• Type: Machinery gene
• Locus tag: VKP39_RS05195
• Genome accession: NZ_CP142353
• Coordinates: 1020309..1022300 (-)
• Length: 663 a.a.
• NCBI ID: WP_002984194.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain D641
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1015309..1027300

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VKP39_RS05170 (VKP39_05170)	dltD	1015599..1016849 (-)	1251	WP_002984219.1	D-alanyl-lipoteichoic acid biosynthesis protein DltD	-
VKP39_RS05175 (VKP39_05175)	dltC	1016842..1017081 (-)	240	WP_002984216.1	D-alanine--poly(phosphoribitol) ligase subunit DltC	-
VKP39_RS05180 (VKP39_05180)	dltB	1017099..1018355 (-)	1257	WP_002994626.1	D-alanyl-lipoteichoic acid biosynthesis protein DltB	-
VKP39_RS05185 (VKP39_05185)	dltA	1018352..1019890 (-)	1539	WP_020837260.1	D-alanine--poly(phosphoribitol) ligase subunit DltA	-
VKP39_RS05190 (VKP39_05190)	-	1019902..1020045 (-)	144	WP_002984200.1	teichoic acid D-Ala incorporation-associated protein DltX	-
VKP39_RS05195 (VKP39_05195)	uvrB	1020309..1022300 (-)	1992	WP_002984194.1	excinuclease ABC subunit UvrB	Machinery gene
VKP39_RS05200 (VKP39_05200)	-	1022493..1024667 (+)	2175	WP_002984191.1	ABC transporter substrate-binding protein/permease	-
VKP39_RS05205 (VKP39_05205)	-	1024667..1025407 (+)	741	WP_002989563.1	amino acid ABC transporter ATP-binding protein	-
VKP39_RS05210 (VKP39_05210)	-	1025555..1025707 (-)	153	WP_003062002.1	hypothetical protein	-
VKP39_RS05215 (VKP39_05215)	-	1025704..1027083 (-)	1380	WP_011285591.1	PTS sugar transporter subunit IIC	-

Sequence

Protein

• Length: 663 a.a.
• Molecular weight: 75654.68 Da
• Isoelectric Point: 4.6420

>NTDB_id=840419 VKP39_RS05195 WP_002984194.1 1020309..1022300(-) (uvrB) [Streptococcus pyogenes strain D641]
MIDKRDDKPFKLKSKYKPSGDQPQAIESLVDNIEGGEKAQILLGATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYG
EFKEFFPDNAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEYA
DSAVSLRPGQEISRDTLLNQLVDIQFERNDIDFQRGCFRVRGDVVEVFPASRDEHAFRVEFFGDEIDRICEIESLTGKTI
GEVDHLVLFPATHFVTNDEHMEQSIAKIQAELAEQLQLFESEGKLLEAQRLRQRTEYDIEMLREMGYTSGVENYSRHMDG
RSPGEPPYTLLDFFPEDFLIMIDESHMTMGQIKGMYNGDQARKQMLVDYGFRLPSALDNRPLRREEFESHVHQIVYVSAT
PGEYEMSQTNTIIEQIIRPTGLLDPEIDVRSSMGQMDDLLGEINQRVARDERTFITTLTKKMAEDLTDYLKEMGVKVKYM
HSDIKTLERTEIIRDLRLGVFDVLIGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNVDGHVIMYADK
MTDSMQRAIDETARRREIQIAYNKAHGIVPQTIKKDIRGLISISKTSHNDISKEEMDYESMSRGERKEAINALQKQMQEA
AELLDFELAAQMRDLILELKLMD

Nucleotide

• Length: 1992 bp

>NTDB_id=840419 VKP39_RS05195 WP_002984194.1 1020309..1022300(-) (uvrB) [Streptococcus pyogenes strain D641]
ATGATTGATAAACGTGATGATAAACCATTTAAACTAAAATCAAAGTATAAACCGTCTGGTGATCAGCCACAAGCTATTGA
AAGCCTAGTTGATAATATCGAGGGCGGAGAAAAAGCTCAGATTCTCCTAGGTGCTACAGGAACGGGAAAAACATACACCA
TGAGCCAAGTAATTAGTAAAGTAAATAAACCTACCTTAGTGATAGCTCACAATAAAACCTTAGCAGGACAATTATATGGT
GAATTTAAAGAATTTTTTCCAGACAATGCTGTGGAATATTTTGTTTCTTATTATGATTACTACCAACCTGAAGCATATGT
CCCATCAAGCGACACCTATATCGAAAAAGATAGTTCAGTCAATGATGAAATCGATAAACTTCGCCATTCAGCCACCTCTT
CTTTACTTGAGCGTAACGATGTCATAGTGGTAGCTTCTGTATCTTGTATTTATGGACTAGGTTCGCCAAAAGAGTACGCA
GATTCAGCAGTCAGCCTACGTCCAGGTCAGGAGATATCACGTGACACTTTGCTAAATCAATTAGTAGATATTCAATTTGA
GCGTAATGATATTGATTTTCAACGCGGCTGTTTTCGTGTACGTGGCGATGTTGTTGAGGTCTTTCCAGCATCCAGGGATG
AACATGCTTTTCGGGTGGAATTTTTCGGGGATGAGATTGACCGTATATGTGAAATCGAAAGTTTAACTGGGAAAACTATT
GGAGAAGTTGACCATTTGGTTTTATTTCCAGCTACTCACTTTGTAACAAATGATGAGCATATGGAGCAATCAATAGCCAA
AATTCAAGCAGAGTTAGCAGAGCAGTTACAGTTATTTGAATCTGAAGGTAAACTACTAGAAGCACAGCGATTACGCCAAA
GAACGGAATATGATATTGAAATGTTACGTGAAATGGGCTATACTAGCGGAGTCGAAAACTATTCCCGTCATATGGATGGC
AGGTCACCAGGAGAACCTCCTTATACCTTGTTAGATTTCTTCCCAGAAGATTTTTTAATTATGATTGATGAAAGTCACAT
GACAATGGGACAAATCAAAGGCATGTATAATGGTGACCAAGCCAGAAAACAAATGCTAGTTGACTATGGTTTTCGATTGC
CATCAGCTCTTGATAATCGTCCCTTAAGACGCGAGGAATTTGAAAGTCATGTGCACCAAATTGTCTATGTTTCAGCAACG
CCTGGTGAATACGAAATGTCACAGACTAATACAATTATTGAGCAAATTATTCGTCCGACTGGGCTACTTGATCCTGAAAT
TGATGTAAGGTCAAGTATGGGGCAAATGGATGATTTGTTGGGAGAAATTAACCAGCGCGTAGCGCGCGATGAACGGACGT
TCATCACAACCTTAACTAAAAAAATGGCAGAAGATTTGACTGATTATCTAAAAGAGATGGGTGTCAAGGTCAAGTATATG
CACAGTGATATTAAAACCTTAGAGCGAACAGAAATTATTCGTGATTTACGACTTGGTGTTTTTGATGTCTTGATTGGAAT
CAATCTGCTCCGTGAAGGGATTGATGTGCCAGAAGTTAGTCTTGTAGCCATTTTGGATGCTGATAAAGAGGGTTTCCTCC
GTAATGAACGCGGCTTGATTCAGACCATCGGTAGAGCAGCTCGAAACGTAGATGGTCATGTCATTATGTATGCGGACAAG
ATGACAGATTCTATGCAGCGAGCTATTGACGAAACGGCTCGTCGTCGTGAGATTCAAATAGCATATAACAAAGCGCACGG
CATCGTTCCACAAACTATAAAAAAAGACATCAGAGGCCTTATTAGTATAAGTAAAACAAGCCACAATGATATATCAAAAG
AAGAGATGGATTATGAAAGTATGTCAAGAGGAGAACGAAAAGAAGCGATCAATGCTCTGCAAAAACAAATGCAAGAGGCA
GCTGAATTACTTGATTTCGAATTGGCAGCTCAAATGCGAGACTTGATTTTAGAACTTAAATTAATGGACTAG

Domains

Predicted by InterProScan.

• Ultra-violet resistance protein B (UvrB) (556-598)

• UvrB interaction domain (UvrB_inter) (164-254)

• Helicase conserved C-terminal domain (Helicase_C) (443-548)

• UvrB/uvrC motif (UVR) (627-660)

• Type III restriction enzyme, res subunit (ResIII) (17-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrB	Streptococcus pneumoniae R6	84.917	100	0.849
uvrB	Streptococcus pneumoniae D39	84.917	100	0.849
uvrB	Streptococcus pneumoniae TIGR4	84.766	100	0.848