Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   VKP35_RS06030 Genome accession   NZ_CP142349
Coordinates   1169388..1171379 (-) Length   663 a.a.
NCBI ID   WP_002989569.1    Uniprot ID   P0DH39
Organism   Streptococcus pyogenes strain 11RS100     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1164388..1176379
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VKP35_RS06005 (VKP35_06005) dltD 1164678..1165928 (-) 1251 WP_002984219.1 D-alanyl-lipoteichoic acid biosynthesis protein DltD -
  VKP35_RS06010 (VKP35_06010) dltC 1165921..1166160 (-) 240 WP_002984216.1 D-alanine--poly(phosphoribitol) ligase subunit DltC -
  VKP35_RS06015 (VKP35_06015) dltB 1166178..1167434 (-) 1257 WP_002984207.1 D-alanyl-lipoteichoic acid biosynthesis protein DltB -
  VKP35_RS06020 (VKP35_06020) dltA 1167431..1168969 (-) 1539 WP_326622445.1 D-alanine--poly(phosphoribitol) ligase subunit DltA -
  VKP35_RS06025 (VKP35_06025) - 1168981..1169124 (-) 144 WP_002984200.1 teichoic acid D-Ala incorporation-associated protein DltX -
  VKP35_RS06030 (VKP35_06030) uvrB 1169388..1171379 (-) 1992 WP_002989569.1 excinuclease ABC subunit UvrB Machinery gene
  VKP35_RS06035 (VKP35_06035) - 1171572..1173746 (+) 2175 WP_002984191.1 ABC transporter substrate-binding protein/permease -
  VKP35_RS06040 (VKP35_06040) - 1173746..1174486 (+) 741 WP_002984187.1 amino acid ABC transporter ATP-binding protein -
  VKP35_RS06045 (VKP35_06045) - 1174633..1174755 (-) 123 WP_002984182.1 hypothetical protein -
  VKP35_RS06050 (VKP35_06050) - 1174781..1176160 (-) 1380 WP_111713289.1 PTS sugar transporter subunit IIC -

Sequence

Protein


Download         Length: 663 a.a.        Molecular weight: 75664.72 Da        Isoelectric Point: 4.6420

>NTDB_id=840048 VKP35_RS06030 WP_002989569.1 1169388..1171379(-) (uvrB) [Streptococcus pyogenes strain 11RS100]
MIDKRDDKPFKLKSKYKPSGDQPQAIESLVDNIEGGEKAQILLGATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYG
EFKEFFPDNAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEYA
DSAVSLRPGQEISRDTLLNQLVDIQFERNDIDFQRGCFRVRGDVVEVFPASRDEHAFRVEFFGDEIDRICEIESLTGKTI
GEVDHLVLFPATHFVTNDEHMEQSIAKIQAELAEQLQLFESEGKLLEAQRLRQRTEYDIEMLREMGYTSGVENYSRHMDG
RSPGEPPYTLLDFFPEDFLIMIDESHMTMGQIKGMYNGDQARKQMLVDYGFRLPSALDNRPLRREEFESHVHQIVYVSAT
PGEYEMSQTNTIIEQIIRPTGLLDPEIDVRPSMGQMDDLLGEINQRVARDERTFITTLTKKMAEDLTDYLKEMGVKVKYM
HSDIKTLERTEIIRDLRLGVFDVLIGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNVDGHVIMYADK
MTDSMQRAIDETARRREIQIAYNKAHGIVPQTIKKDIRGLISISKTSHNDISKEEMDYESMSRGERKEAINALQKQMQEA
AELLDFELAAQMRDLILELKLMD

Nucleotide


Download         Length: 1992 bp        

>NTDB_id=840048 VKP35_RS06030 WP_002989569.1 1169388..1171379(-) (uvrB) [Streptococcus pyogenes strain 11RS100]
ATGATTGATAAACGTGATGATAAACCATTTAAACTAAAATCAAAGTATAAACCGTCTGGTGATCAGCCACAAGCTATTGA
AAGCCTAGTTGATAATATCGAGGGCGGAGAAAAAGCTCAGATTCTCCTAGGTGCTACAGGAACGGGAAAAACATACACCA
TGAGCCAAGTAATTAGTAAAGTAAATAAACCTACCTTAGTGATAGCTCACAATAAAACCTTAGCAGGACAATTATATGGT
GAATTTAAAGAATTTTTTCCAGACAATGCTGTGGAATATTTTGTTTCCTATTATGATTACTACCAACCTGAAGCATATGT
CCCATCAAGCGACACCTATATCGAAAAAGATAGTTCAGTCAATGATGAAATCGATAAACTTCGCCATTCAGCCACCTCTT
CTTTACTTGAGCGTAACGATGTCATAGTGGTAGCTTCTGTATCTTGTATTTATGGACTAGGTTCGCCAAAAGAGTACGCA
GATTCAGCAGTCAGTCTACGTCCAGGTCAGGAGATATCACGTGACACTTTGCTAAATCAATTAGTAGATATTCAATTTGA
GCGTAATGATATTGATTTTCAACGCGGCTGTTTTCGTGTACGTGGCGATGTTGTTGAGGTCTTTCCAGCATCCAGGGATG
AACATGCTTTTCGGGTGGAATTTTTCGGGGATGAGATTGACCGTATATGTGAAATCGAAAGTTTAACTGGGAAAACTATT
GGAGAAGTTGATCATTTGGTTTTATTTCCAGCTACTCACTTTGTAACAAATGACGAGCATATGGAGCAATCAATAGCCAA
AATTCAAGCAGAGTTAGCAGAGCAGTTACAGTTATTTGAATCTGAAGGTAAACTACTAGAAGCACAGCGATTACGCCAAA
GAACGGAATATGATATTGAAATGTTACGTGAAATGGGCTATACTAGCGGAGTCGAAAACTATTCCCGTCATATGGATGGC
AGGTCACCAGGAGAACCTCCTTATACCTTGTTAGATTTCTTCCCAGAAGATTTTTTAATTATGATTGATGAAAGTCACAT
GACAATGGGACAAATCAAAGGCATGTATAATGGTGACCAAGCCAGAAAACAAATGCTAGTTGACTATGGTTTTCGATTGC
CATCAGCTCTTGATAATCGTCCCTTAAGACGCGAGGAATTTGAAAGTCATGTGCACCAAATTGTCTATGTTTCAGCAACG
CCTGGTGAATACGAAATGTCACAGACTAATACAATTATTGAGCAAATTATTCGTCCGACTGGGCTACTTGATCCTGAAAT
TGATGTAAGGCCAAGTATGGGGCAAATGGATGATTTGTTGGGAGAAATTAACCAGCGCGTAGCGCGCGATGAACGGACGT
TCATCACAACCTTAACTAAAAAAATGGCAGAAGATTTGACTGATTATCTAAAAGAGATGGGTGTCAAGGTCAAGTATATG
CACAGTGATATTAAAACCTTAGAGCGGACAGAAATTATTCGTGATTTACGACTTGGTGTTTTTGATGTCTTGATTGGAAT
CAATCTGCTCCGTGAAGGGATTGATGTGCCAGAAGTTAGTCTTGTAGCCATTTTGGATGCTGATAAAGAGGGTTTCCTCC
GTAATGAACGCGGCTTGATTCAGACCATCGGTAGAGCAGCTCGAAACGTAGATGGTCATGTCATTATGTATGCGGACAAG
ATGACAGATTCTATGCAGCGAGCTATTGACGAAACGGCTCGTCGTCGTGAGATTCAAATAGCATATAACAAAGCGCACGG
CATCGTTCCACAAACTATAAAAAAAGACATCAGAGGCCTTATTAGTATAAGTAAAACAAGCCACAATGATATATCAAAAG
AAGAGATGGATTATGAAAGTATGTCAAGAGGAGAACGAAAAGAAGCGATCAATGCTCTGCAAAAACAAATGCAAGAGGCA
GCTGAATTACTTGATTTCGAATTGGCAGCTCAAATGCGAGACTTGATTTTAGAACTTAAATTAATGGACTAG

Domains

Predicted by InterProScan.

Ultra-violet resistance protein B (UvrB)

(556-598)

UvrB interaction domain (UvrB_inter)

(164-254)

Helicase conserved C-terminal domain (Helicase_C)

(443-548)

Type III restriction enzyme, res subunit (ResIII)

(17-142)

UvrB/uvrC motif (UVR)

(627-660)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0DH39

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

85.068

100

0.851
  uvrB Streptococcus pneumoniae D39

85.068

100

0.851
  uvrB Streptococcus pneumoniae TIGR4

84.917

100

0.849