Detailed information NTG0083943

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: JN157_RS09080
• Genome accession: NZ_AP024200
• Coordinates: 1914226..1915269 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus argenteus strain Tokyo13064
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1909226..1920269

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JN157_RS09050 (TMSFP064_17340)	-	1909637..1910884 (-)	1248	WP_000656301.1	aminopeptidase	-
JN157_RS09055 (TMSFP064_17350)	-	1910896..1911096 (-)	201	WP_000180459.1	DUF1128 family protein	-
JN157_RS09060 (TMSFP064_17360)	-	1911243..1911707 (+)	465	WP_000228669.1	low molecular weight protein-tyrosine-phosphatase	-
JN157_RS09065 (TMSFP064_17370)	-	1911714..1911989 (+)	276	WP_000428174.1	YtxH domain-containing protein	-
JN157_RS09070 (TMSFP064_17380)	-	1912268..1913491 (+)	1224	WP_000037065.1	YihY/virulence factor BrkB family protein	-
JN157_RS09075 (TMSFP064_17390)	vraR	1913607..1914236 (-)	630	WP_000153529.1	two-component system response regulator VraR	Regulator
JN157_RS09080 (TMSFP064_17400)	vraS	1914226..1915269 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
JN157_RS09085 (TMSFP064_17410)	liaF	1915266..1915967 (-)	702	WP_047528366.1	cell wall-active antibiotics response protein LiaF	-
JN157_RS09090 (TMSFP064_17420)	-	1915982..1916368 (-)	387	WP_047528367.1	hypothetical protein	-
JN157_RS09095 (TMSFP064_17430)	map	1916622..1917380 (-)	759	WP_031788218.1	type I methionyl aminopeptidase	-
JN157_RS09100 (TMSFP064_17440)	-	1917904..1918890 (+)	987	WP_047557232.1	FUSC family protein	-
JN157_RS09105 (TMSFP064_17450)	-	1919292..1919672 (-)	381	WP_225995313.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=83943 JN157_RS09080 WP_001017131.1 1914226..1915269(-) (vraS) [Staphylococcus argenteus strain Tokyo13064]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=83943 JN157_RS09080 WP_001017131.1 1914226..1915269(-) (vraS) [Staphylococcus argenteus strain Tokyo13064]
ATGAACCATTATATTAGAACAATTGGTTCGATGCTCATCTTAGTATACAGCATGCTAGCGGCATTTCTTTTTATAGATAA
AGTTTTCGTTAATATTATTTATTTTCAAGGCATGTTTTATACACAAATATTTGGGATTCCAGTCTTTTTATTTTTAAATC
TCATTATCATTTTATTGTGTATCATCGTTGGATCGGTGCTTGCCTACAAAATTAATCAACAAAATGACTGGATTAAGACA
CAAATTGAGCGTTCTATGGAAGGCGAAACAGTAGGTATCAATGATCAAAATATAGAAATATATAGTGAAACATTAGATTT
ATATCATACGTTAGTACCTTTAAATCAAGAATTGCATAAGTTAAGACTCAAAACGCAAAATTTAACAAATGAAAATTACA
ATATTAATGATGTTAAAGTTAAAAAGATTATCGAAGATGAAAGACAACGTTTAGCTAGAGAACTACACGACTCTGTTAGT
CAACAACTTTTTGCGGCAAGTATGATGTTATCTGCAATTAAAGAAACAAAATTAGAACCACCTTTAGATCAACAAATACC
TATTTTAGAGAAAATGGTTCAAGATTCTCAGTTAGAAATGCGTGCTCTGCTGCTACACTTAAGACCACTCGGCTTGAAAG
ATAAGTCATTAGGCGAAGGTATTAAAGATTTAGTTATTGATTTACAAAAGAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCAAAAGGTATTGAGGATCATTTATTTAGAATTACGCAAGAAGCAATATCTAATACATTGAGACA
TTCAAATGGTACGAAAGTAACTGTAGAATTATTTAATAAAGATGATTATTTATTGTTAAGGATACAAGATAATGGTAAAG
GTTTTAATGTAGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCACTACCAGATTCAGGTACACGTATTGAGGTGAAAGCACCTCTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1