Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   VJ737_RS19270 Genome accession   NZ_CP141909
Coordinates   4264536..4265222 (-) Length   228 a.a.
NCBI ID   WP_184594412.1    Uniprot ID   A0A7W4ZSY7
Organism   Streptomyces sp. CGMCC 4.1772     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4259536..4270222
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VJ737_RS19250 (VJ737_19250) - 4260943..4261167 (+) 225 WP_229845494.1 hypothetical protein -
  VJ737_RS19255 (VJ737_19255) - 4261151..4262368 (-) 1218 WP_184594418.1 cytochrome P450 -
  VJ737_RS19260 (VJ737_19260) vraR 4262437..4263102 (-) 666 WP_184594416.1 response regulator transcription factor Regulator
  VJ737_RS19265 (VJ737_19265) - 4263099..4264436 (-) 1338 WP_184594414.1 histidine kinase -
  VJ737_RS19270 (VJ737_19270) vraR 4264536..4265222 (-) 687 WP_184594412.1 response regulator transcription factor Regulator
  VJ737_RS19275 (VJ737_19275) - 4265219..4266610 (-) 1392 WP_184594410.1 sensor histidine kinase -
  VJ737_RS19280 (VJ737_19280) - 4266603..4267832 (-) 1230 WP_184594408.1 acyltransferase -
  VJ737_RS19285 (VJ737_19285) - 4267825..4268826 (-) 1002 WP_184594406.1 alpha/beta hydrolase -
  VJ737_RS19290 (VJ737_19290) - 4269012..4269878 (-) 867 WP_184594404.1 alpha/beta hydrolase -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 24497.16 Da        Isoelectric Point: 4.6905

>NTDB_id=838702 VJ737_RS19270 WP_184594412.1 4264536..4265222(-) (vraR) [Streptomyces sp. CGMCC 4.1772]
MTSGGTGDPIRVLIVDDQAMVRQGFTVLLGIQPDIEVVGEAREGREAIAKAAETAPDVVLMDIRMPGVGGIEATELITAA
HPDIKVLVLTTFDLDEYVYDALRAGASGFLLKDASSEQLAEAVRVVAAGEALLAPVITRKLIAEFSRLDDRPRAPLKERI
GDLTERETEVLALIAQGLSNGEIARHLFVAEQTVKTHVGRILVKLGLRDRTQAAVFAYESGLVRPSGY

Nucleotide


Download         Length: 687 bp        

>NTDB_id=838702 VJ737_RS19270 WP_184594412.1 4264536..4265222(-) (vraR) [Streptomyces sp. CGMCC 4.1772]
ATGACGAGCGGCGGCACCGGCGATCCCATCCGGGTACTCATCGTCGACGACCAGGCGATGGTCCGGCAGGGCTTCACCGT
GCTGCTCGGCATCCAGCCCGACATAGAGGTCGTCGGCGAGGCGCGGGAGGGCCGGGAAGCCATCGCGAAGGCCGCCGAGA
CCGCCCCGGACGTCGTCCTCATGGACATCCGCATGCCCGGGGTCGGCGGTATCGAGGCCACCGAGCTGATCACGGCCGCG
CACCCGGACATCAAGGTGCTGGTGCTCACCACCTTCGACCTCGACGAGTACGTGTACGACGCGCTGCGCGCCGGGGCCTC
CGGGTTCCTGCTGAAGGACGCGTCGTCGGAGCAGCTGGCCGAGGCGGTCCGGGTGGTGGCGGCCGGGGAGGCGCTGCTCG
CCCCGGTCATCACCCGCAAGCTGATCGCCGAGTTCTCCCGGCTGGACGACCGGCCCCGAGCCCCGCTCAAGGAACGCATC
GGCGACCTGACCGAGCGGGAGACGGAGGTGCTCGCCCTGATCGCGCAGGGCCTGTCGAACGGGGAGATCGCCCGGCACCT
CTTCGTCGCCGAGCAGACGGTGAAGACCCACGTGGGCCGGATCCTGGTGAAGCTGGGCCTCAGGGACCGGACGCAGGCGG
CGGTGTTCGCGTACGAGTCGGGGCTGGTACGGCCCTCGGGGTACTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(12-124)

Bacterial regulatory proteins, luxR family (GerE)

(163-217)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7W4ZSY7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

47.442

94.298

0.447
  degU Bacillus subtilis subsp. subtilis str. 168

41.256

97.807

0.404