Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   VJ737_RS19260 Genome accession   NZ_CP141909
Coordinates   4262437..4263102 (-) Length   221 a.a.
NCBI ID   WP_184594416.1    Uniprot ID   A0ABZ1NW25
Organism   Streptomyces sp. CGMCC 4.1772     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4257437..4268102
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VJ737_RS19235 (VJ737_19235) - 4257815..4258312 (-) 498 WP_184594426.1 MarR family transcriptional regulator -
  VJ737_RS19240 (VJ737_19240) - 4258387..4259301 (+) 915 WP_184594424.1 ABC transporter ATP-binding protein -
  VJ737_RS19245 (VJ737_19245) - 4259298..4260896 (+) 1599 WP_184594422.1 ABC transporter permease -
  VJ737_RS19250 (VJ737_19250) - 4260943..4261167 (+) 225 WP_229845494.1 hypothetical protein -
  VJ737_RS19255 (VJ737_19255) - 4261151..4262368 (-) 1218 WP_184594418.1 cytochrome P450 -
  VJ737_RS19260 (VJ737_19260) vraR 4262437..4263102 (-) 666 WP_184594416.1 response regulator transcription factor Regulator
  VJ737_RS19265 (VJ737_19265) - 4263099..4264436 (-) 1338 WP_184594414.1 histidine kinase -
  VJ737_RS19270 (VJ737_19270) vraR 4264536..4265222 (-) 687 WP_184594412.1 response regulator transcription factor Regulator
  VJ737_RS19275 (VJ737_19275) - 4265219..4266610 (-) 1392 WP_184594410.1 sensor histidine kinase -
  VJ737_RS19280 (VJ737_19280) - 4266603..4267832 (-) 1230 WP_184594408.1 acyltransferase -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 23948.70 Da        Isoelectric Point: 4.5842

>NTDB_id=838701 VJ737_RS19260 WP_184594416.1 4262437..4263102(-) (vraR) [Streptomyces sp. CGMCC 4.1772]
MTIRVLIADDQMMVREGFSVLLNAMPDIEVVGEAVNGREAVAKVRELAPDVVLMDIRMPELNGIEATREIVAADGEAKVL
VLTTFDLDEYVYQALRAGASGFLLKDASARQLADGVRIVATGEALLAPSVTRRLITEFSKLSETPRLMPSAQAAYGDLTD
RETEVLVLIAQGLSNAEIAERLVVAESTIKTHVSRILVKLGLRDRTQAAVFAYEARLVTPG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=838701 VJ737_RS19260 WP_184594416.1 4262437..4263102(-) (vraR) [Streptomyces sp. CGMCC 4.1772]
ATGACCATTCGCGTACTGATCGCGGACGATCAGATGATGGTGCGCGAGGGCTTCTCGGTCCTGCTGAACGCGATGCCGGA
CATCGAGGTCGTCGGCGAGGCGGTGAACGGCCGGGAGGCCGTCGCGAAGGTCCGCGAACTCGCCCCGGACGTCGTGCTGA
TGGACATCCGCATGCCCGAGCTGAACGGCATCGAGGCGACCCGCGAGATCGTCGCCGCCGACGGCGAGGCGAAAGTGCTG
GTGCTCACCACCTTCGACCTCGACGAATACGTGTACCAGGCGCTGCGCGCGGGAGCCTCCGGCTTCCTCCTCAAGGACGC
CTCGGCCCGCCAGCTCGCCGACGGGGTGCGGATCGTGGCCACCGGGGAGGCCCTTCTGGCCCCCTCGGTGACCAGGCGAC
TGATCACCGAGTTCTCCAAGCTCTCCGAGACCCCGCGCCTGATGCCCTCCGCGCAGGCCGCGTACGGCGACCTCACCGAC
CGGGAGACGGAGGTGCTGGTCCTCATCGCGCAAGGCCTGTCGAACGCGGAGATCGCCGAGCGGCTGGTGGTCGCCGAGTC
GACGATCAAGACCCACGTCAGCCGGATCCTGGTGAAGCTGGGGCTGAGGGACCGCACCCAGGCGGCGGTGTTCGCCTACG
AGGCGCGGCTGGTGACGCCCGGCTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(158-212)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.954

98.643

0.443
  degU Bacillus subtilis subsp. subtilis str. 168

42.857

98.19

0.421