Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   QMK35_RS04860 Genome accession   NZ_CP126540
Coordinates   1048773..1049402 (+) Length   209 a.a.
NCBI ID   WP_019469616.1    Uniprot ID   A0A6N7XUN7
Organism   Staphylococcus cohnii strain SDAQ-1     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1043773..1054402
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QMK35_RS04830 (QMK35_04830) - 1043808..1044530 (+) 723 WP_064264271.1 type 1 glutamine amidotransferase -
  QMK35_RS04835 (QMK35_04835) - 1044619..1045605 (-) 987 WP_064264273.1 aromatic acid exporter family protein -
  QMK35_RS04840 (QMK35_04840) map 1045782..1046534 (+) 753 WP_064264275.1 type I methionyl aminopeptidase -
  QMK35_RS04845 (QMK35_04845) - 1046639..1047025 (+) 387 WP_019469613.1 hypothetical protein -
  QMK35_RS04850 (QMK35_04850) liaF 1047042..1047743 (+) 702 WP_019469614.1 cell wall-active antibiotics response protein LiaF -
  QMK35_RS04855 (QMK35_04855) vraS 1047740..1048783 (+) 1044 WP_019469615.1 sensor histidine kinase Regulator
  QMK35_RS04860 (QMK35_04860) vraR 1048773..1049402 (+) 630 WP_019469616.1 response regulator transcription factor Regulator
  QMK35_RS04865 (QMK35_04865) - 1049490..1050569 (-) 1080 WP_064264279.1 YihY/virulence factor BrkB family protein -
  QMK35_RS04870 (QMK35_04870) - 1050880..1051164 (-) 285 WP_019469618.1 YtxH domain-containing protein -
  QMK35_RS04875 (QMK35_04875) - 1051172..1051636 (-) 465 WP_064264281.1 low molecular weight protein-tyrosine-phosphatase -
  QMK35_RS04880 (QMK35_04880) - 1051769..1051972 (+) 204 WP_064264282.1 DUF1128 family protein -
  QMK35_RS04885 (QMK35_04885) - 1051987..1053225 (+) 1239 WP_150889860.1 aminopeptidase -
  QMK35_RS04890 (QMK35_04890) - 1053383..1053904 (+) 522 WP_064264286.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23774.31 Da        Isoelectric Point: 4.7152

>NTDB_id=838670 QMK35_RS04860 WP_019469616.1 1048773..1049402(+) (vraR) [Staphylococcus cohnii strain SDAQ-1]
MPIKVLFVDDHEMVRIGISSYLSTQPDIEVVGEGQSGKDAIEKAHELKPDLILMDLLMDDMDGVEATEQIKKDLPHIKVV
MLTSYIEDNEVYRALDSGVDSYILKTTSASDIAEAIRKTYRDESVFEAEVLVKMRNRMKQRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNVLSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=838670 QMK35_RS04860 WP_019469616.1 1048773..1049402(+) (vraR) [Staphylococcus cohnii strain SDAQ-1]
ATGCCGATTAAAGTATTATTTGTTGATGATCATGAAATGGTCAGAATTGGTATTTCTAGTTATTTATCTACTCAACCAGA
TATAGAAGTAGTCGGAGAAGGGCAATCAGGGAAAGATGCAATTGAAAAAGCACATGAACTAAAACCTGATTTAATTTTAA
TGGACTTACTGATGGATGATATGGATGGTGTAGAAGCTACAGAACAAATTAAGAAAGATTTGCCACACATTAAAGTCGTT
ATGCTAACTAGTTATATTGAAGATAATGAAGTGTACCGTGCACTAGATTCTGGCGTAGATAGCTATATTTTAAAAACAAC
AAGTGCCAGTGATATCGCTGAAGCGATACGCAAAACATATCGTGATGAATCTGTATTTGAAGCAGAAGTGCTGGTTAAGA
TGAGAAATCGTATGAAACAACGCGCTGAATTATATGAGATGTTAACTGAGCGTGAAATGGAAATATTATTATTGATTGCA
AAAGGGTACTCAAACCAAGAAATTGCCAGTGCTTCACATATTACAATCAAAACAGTTAAAACACATGTGAGTAACGTATT
GAGCAAATTAGAAGTACAAGATAGAACTCAAGCTGTAATCTATGCATTTCAACATAATTTAATACAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6N7XUN7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

90.431

100

0.904
  degU Bacillus subtilis subsp. subtilis str. 168

33.929

100

0.364