Detailed information NTG0838669

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: QMK35_RS04855
• Genome accession: NZ_CP126540
• Coordinates: 1047740..1048783 (+)
• Length: 347 a.a.
• NCBI ID: WP_019469615.1
• Uniprot ID: A0A6N7XY82
• Organism: Staphylococcus cohnii strain SDAQ-1
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1042740..1053783

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QMK35_RS04830 (QMK35_04830)	-	1043808..1044530 (+)	723	WP_064264271.1	type 1 glutamine amidotransferase	-
QMK35_RS04835 (QMK35_04835)	-	1044619..1045605 (-)	987	WP_064264273.1	aromatic acid exporter family protein	-
QMK35_RS04840 (QMK35_04840)	map	1045782..1046534 (+)	753	WP_064264275.1	type I methionyl aminopeptidase	-
QMK35_RS04845 (QMK35_04845)	-	1046639..1047025 (+)	387	WP_019469613.1	hypothetical protein	-
QMK35_RS04850 (QMK35_04850)	liaF	1047042..1047743 (+)	702	WP_019469614.1	cell wall-active antibiotics response protein LiaF	-
QMK35_RS04855 (QMK35_04855)	vraS	1047740..1048783 (+)	1044	WP_019469615.1	sensor histidine kinase	Regulator
QMK35_RS04860 (QMK35_04860)	vraR	1048773..1049402 (+)	630	WP_019469616.1	response regulator transcription factor	Regulator
QMK35_RS04865 (QMK35_04865)	-	1049490..1050569 (-)	1080	WP_064264279.1	YihY/virulence factor BrkB family protein	-
QMK35_RS04870 (QMK35_04870)	-	1050880..1051164 (-)	285	WP_019469618.1	YtxH domain-containing protein	-
QMK35_RS04875 (QMK35_04875)	-	1051172..1051636 (-)	465	WP_064264281.1	low molecular weight protein-tyrosine-phosphatase	-
QMK35_RS04880 (QMK35_04880)	-	1051769..1051972 (+)	204	WP_064264282.1	DUF1128 family protein	-
QMK35_RS04885 (QMK35_04885)	-	1051987..1053225 (+)	1239	WP_150889860.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40030.41 Da
• Isoelectric Point: 5.8532

>NTDB_id=838669 QMK35_RS04855 WP_019469615.1 1047740..1048783(+) (vraS) [Staphylococcus cohnii strain SDAQ-1]
MNHYIRAIGSMLILVYSTFFAMFFIDKVFVNIIYFQGMIYTQIFGIPVLLFINLLVILLCIIVGSVLAYKINQQNHWLQD
QIERSIEGQTVGINDQNIELYNETIELYQTLVPLNQEVHRLRLKTQNLTNESYNMNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETDLKAPLDQQIPVLEKMIQDSQLEMRALLLHLRPIGLKDKSLGQGIKDLVVDLQKKVPMKVVHDI
EEFDVPKGIEDHLFRITQEAISNTLRHSKGTKVTIELFNREEYLLLRIQDDGKGFNVDDKVEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYAD

Nucleotide

• Length: 1044 bp

>NTDB_id=838669 QMK35_RS04855 WP_019469615.1 1047740..1048783(+) (vraS) [Staphylococcus cohnii strain SDAQ-1]
ATGAATCACTACATAAGAGCAATAGGGTCAATGTTGATATTAGTTTATAGTACATTTTTCGCTATGTTTTTTATAGATAA
AGTTTTTGTGAATATTATATATTTTCAAGGCATGATTTATACGCAAATCTTTGGAATACCAGTTTTACTATTTATTAACT
TATTAGTTATATTACTTTGCATCATTGTTGGCTCAGTATTAGCTTATAAAATCAATCAACAAAATCATTGGTTACAAGAC
CAAATTGAGCGTTCTATAGAAGGGCAGACAGTAGGTATCAATGACCAAAATATAGAATTATATAATGAAACAATTGAATT
ATATCAAACGCTTGTACCGCTCAATCAAGAAGTTCATAGATTGCGTTTAAAAACACAAAATTTAACGAATGAATCATATA
ATATGAACGATGTGAAAGTTAAAAAAATAATTGAAGATGAAAGACAAAGACTGGCTCGAGAGTTACATGATTCCGTAAGC
CAGCAATTGTTTGCAGCAAGCATGATGCTCTCTGCCATTAAAGAAACTGATTTGAAAGCGCCTTTAGATCAACAAATTCC
AGTATTGGAAAAAATGATTCAAGATTCACAGCTAGAAATGCGTGCCTTGCTATTACATTTAAGACCAATTGGCTTGAAAG
ATAAATCACTTGGCCAAGGTATCAAAGATTTAGTGGTTGATTTGCAGAAAAAAGTGCCTATGAAAGTTGTACATGATATT
GAAGAATTCGACGTACCTAAAGGTATAGAAGATCATTTATTTAGAATTACACAAGAAGCAATTTCAAATACATTAAGACA
TTCAAAAGGGACAAAAGTTACAATTGAATTGTTTAATAGAGAAGAATATTTATTATTACGTATACAAGATGATGGTAAAG
GCTTTAACGTAGATGATAAGGTAGAACAAAGCTATGGGTTAAAAAATATGCGCGAACGAGCACTTGAAATTGGCGCAACG
TTTCATATAGTATCACTGCCAGATTCAGGAACACGAATTGAAGTCAAAGCCCCATTAAATAAGGAGGATTCATATGCCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A6N7XY82

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	86.455	100	0.865