Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   VF946_RS09070 Genome accession   NZ_CP141824
Coordinates   1775789..1776430 (-) Length   213 a.a.
NCBI ID   WP_002937025.1    Uniprot ID   A0A0H3MTV8
Organism   Streptococcus suis strain HB18     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1770789..1781430
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VF946_RS09045 comFA/cflA 1770940..1772232 (-) 1293 WP_012774986.1 DEAD/DEAH box helicase Machinery gene
  VF946_RS09050 - 1772289..1772921 (+) 633 WP_014636235.1 YigZ family protein -
  VF946_RS09055 cysK 1773014..1773940 (+) 927 WP_012774985.1 cysteine synthase A -
  VF946_RS09060 - 1773966..1774337 (-) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -
  VF946_RS09065 - 1774339..1775739 (-) 1401 WP_024406021.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  VF946_RS09070 vraR 1775789..1776430 (-) 642 WP_002937025.1 response regulator transcription factor Regulator
  VF946_RS09075 - 1776402..1777418 (-) 1017 WP_002937028.1 sensor histidine kinase -
  VF946_RS09080 liaF 1777415..1778074 (-) 660 WP_223375661.1 cell wall-active antibiotics response protein LiaF -
  VF946_RS11705 - 1778531..1778803 (-) 273 WP_395387773.1 PASTA domain-containing protein -
  VF946_RS09085 pknB 1778867..1780525 (-) 1659 Protein_1754 Stk1 family PASTA domain-containing Ser/Thr kinase -
  VF946_RS09090 - 1780525..1781262 (-) 738 WP_012774983.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23790.36 Da        Isoelectric Point: 4.8970

>NTDB_id=838211 VF946_RS09070 WP_002937025.1 1775789..1776430(-) (vraR) [Streptococcus suis strain HB18]
MNTIRVMLVDDHEMVRLGLKSYLNLQPDVEVVAEASDGEEGLAKALEVKPDVVVMDLVMPKMTGVEATLALLKEWPQAQI
VILTSYLDNEKIYPVLEAGARGYMLKTSSADEILAAIRKVALGEYAIETEVEKKVEHHKRHPDLHDDLTAREREILTLLA
KGYDNQRIADESFISLKTVKTHVSNILSKLAVSDRTQAVVYAFQHGLVAQEDQ

Nucleotide


Download         Length: 642 bp        

>NTDB_id=838211 VF946_RS09070 WP_002937025.1 1775789..1776430(-) (vraR) [Streptococcus suis strain HB18]
ATGAATACGATTCGAGTGATGCTGGTTGACGACCATGAGATGGTTCGCCTAGGATTGAAAAGTTACTTAAATTTACAGCC
AGATGTTGAAGTAGTTGCAGAAGCTAGTGATGGCGAGGAAGGTTTGGCTAAAGCGTTAGAGGTTAAACCTGATGTTGTAG
TGATGGACTTGGTTATGCCCAAGATGACTGGCGTAGAAGCAACTCTGGCCTTGCTGAAGGAATGGCCGCAAGCGCAGATT
GTCATCCTGACCTCCTATCTAGATAATGAGAAAATCTATCCTGTGCTGGAAGCAGGAGCTCGTGGCTATATGTTGAAAAC
GTCAAGTGCTGACGAAATCTTAGCAGCCATCCGCAAGGTAGCTCTTGGAGAATATGCTATTGAGACAGAAGTAGAGAAAA
AAGTAGAGCACCATAAACGCCACCCAGATTTACATGATGACTTGACAGCTCGTGAACGCGAAATCTTGACGCTGTTAGCC
AAGGGATATGATAATCAACGAATTGCAGATGAGTCCTTCATATCCTTAAAAACTGTTAAGACCCATGTTTCCAATATCTT
ATCCAAACTAGCTGTTAGCGATCGTACTCAAGCAGTTGTTTATGCTTTCCAGCATGGTTTGGTGGCGCAAGAGGACCAAT
AG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-202)

Response regulator receiver domain (Response_reg)

(6-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H3MTV8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

54.589

97.183

0.531
  degU Bacillus subtilis subsp. subtilis str. 168

38.938

100

0.413