Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   VA243_RS04250 Genome accession   NZ_CP141774
Coordinates   893372..895348 (-) Length   658 a.a.
NCBI ID   WP_324714287.1    Uniprot ID   -
Organism   Helicobacter pylori strain P07353     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 888372..900348
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VA243_RS04225 - 888459..888851 (+) 393 WP_000656174.1 4Fe-4S dicluster-binding protein -
  VA243_RS04230 - 888862..890085 (+) 1224 WP_324714284.1 2-oxoacid:ferredoxin oxidoreductase subunit alpha -
  VA243_RS04235 - 890098..891042 (+) 945 WP_000238165.1 thiamine pyrophosphate-dependent enzyme -
  VA243_RS04240 purB 891145..892467 (+) 1323 WP_324714285.1 adenylosuccinate lyase -
  VA243_RS04245 - 892528..893361 (+) 834 WP_324714286.1 outer membrane protein -
  VA243_RS04250 uvrB 893372..895348 (-) 1977 WP_324714287.1 excinuclease ABC subunit UvrB Machinery gene
  VA243_RS04255 - 895465..895596 (-) 132 WP_324715115.1 histidinol dehydrogenase -
  VA243_RS04260 - 895570..895993 (-) 424 Protein_826 hypothetical protein -
  VA243_RS04265 - 896505..897275 (-) 771 WP_324714288.1 HP1117 family Sel1-like repeat protein -
  VA243_RS04270 ggt 897542..899245 (-) 1704 WP_120855362.1 gamma-glutamyltransferase -

Sequence

Protein


Download         Length: 658 a.a.        Molecular weight: 75936.34 Da        Isoelectric Point: 6.6988

>NTDB_id=837873 VA243_RS04250 WP_324714287.1 893372..895348(-) (uvrB) [Helicobacter pylori strain P07353]
MPLFDLKSPYPPAGDQPQAIEALTKSLKNNNHYQTLVGVTGSGKTYTMANIIANTNKPTLIMSHNKTLCAQLYSEFKAFF
PHNRVEYFISHFDYYQPESYIPRRDLFIEKDSSINDDLERLRLSATTSLLGYDDVIVIASVSANYGLGNPEEYLKVMEKI
KVGEKHAYKSFLLKLVEMGYSRNEVVFDRGSFRATGECVDIFPAYNDAEFIRIEFFGDEIERIAVFDALEKNEIKRLDSV
MLYAASQFAVGSERLNLAIKSIEDELALRLKFFKEQDKMLEYNRLKQRTEHDLEMISATGVCKGIENYARHFTGKAPNET
PFCLFDYLGIFEREFLVIVDESHVSLPQFGGMYAGDMSRKSVLVEYGFRLPSALDNRPLKFDEFIHKNCQFLFVSATPNK
LELELSQKNVAEQIIRPTGLLDPKFEVRDSDKQVQDLFDEIKLVVARDERVLITTLTKKMAEELCKYYAEWGLKARYMHS
EIDAIERNHIIRSLRLKEFDILIGINLLREGLDLPEVSLVAIMDADKEGFLRSETSLIQTMGRAARNANGKVLLYAKKTT
QSMQKAFEITSYRRAKQEEFNKLHHITPKTVTRTLEEELKLRDDEIKIAKALKKDKIPKSEREKIIKELDKKMRECAKNL
DFEEAMRLRDEIAKLRTL

Nucleotide


Download         Length: 1977 bp        

>NTDB_id=837873 VA243_RS04250 WP_324714287.1 893372..895348(-) (uvrB) [Helicobacter pylori strain P07353]
ATGCCTTTATTTGATTTAAAAAGCCCTTATCCACCAGCAGGCGATCAGCCCCAAGCTATAGAAGCCTTAACGAAGAGCTT
AAAAAATAACAACCATTATCAAACTTTAGTGGGGGTTACAGGGAGCGGTAAGACTTATACGATGGCCAATATCATCGCTA
ATACCAACAAACCCACTCTGATCATGAGCCATAATAAGACCTTATGCGCACAGCTCTATAGCGAGTTTAAGGCGTTTTTC
CCGCATAATAGGGTGGAGTATTTTATCTCCCACTTTGACTACTACCAGCCTGAAAGCTATATCCCTAGAAGGGATTTATT
CATTGAAAAAGACAGCTCTATTAATGATGATTTAGAGCGTTTGAGATTGAGCGCGACCACCTCACTTTTAGGTTATGATG
ATGTGATCGTGATAGCGAGCGTTTCGGCTAATTATGGTTTGGGTAACCCTGAAGAATATTTAAAAGTCATGGAAAAAATC
AAAGTGGGTGAGAAGCACGCTTATAAGAGCTTTTTATTAAAGCTAGTAGAAATGGGTTATAGCCGTAATGAAGTGGTGTT
TGATAGGGGGAGCTTTAGGGCGACCGGAGAATGCGTGGATATTTTCCCCGCTTATAATGACGCTGAATTTATCAGGATTG
AATTTTTTGGCGATGAGATAGAAAGGATTGCTGTCTTTGACGCTTTAGAAAAAAATGAAATCAAGCGCTTGGATTCTGTC
ATGCTTTATGCGGCCAGTCAGTTTGCCGTAGGGAGTGAGAGACTGAATTTAGCCATTAAAAGCATTGAAGATGAACTCGC
TTTAAGATTGAAATTTTTTAAAGAGCAGGATAAAATGCTTGAATACAACCGCCTCAAACAACGCACCGAGCATGATTTAG
AAATGATTAGCGCAACCGGTGTGTGTAAGGGCATTGAAAATTACGCGCGCCATTTTACGGGCAAAGCCCCTAATGAAACG
CCTTTTTGCTTGTTTGATTATTTAGGGATATTTGAGCGGGAGTTTTTAGTCATTGTGGATGAAAGCCATGTGAGTTTGCC
GCAGTTTGGAGGGATGTATGCAGGGGATATGAGCAGGAAAAGCGTTTTAGTGGAATATGGTTTTAGATTGCCTAGCGCTT
TAGACAACCGCCCTTTAAAATTTGATGAATTTATCCATAAAAATTGCCAGTTCCTTTTTGTGTCCGCTACGCCCAATAAG
CTAGAATTAGAGCTTTCTCAAAAGAATGTCGCTGAGCAAATCATTCGCCCTACAGGGCTTTTAGACCCTAAATTTGAAGT
GCGAGACAGCGATAAGCAAGTCCAAGATTTATTTGATGAAATCAAGTTAGTGGTGGCTAGAGATGAAAGGGTGCTTATCA
CCACGCTCACTAAAAAAATGGCAGAAGAATTGTGCAAATATTATGCCGAATGGGGCTTGAAAGCGCGTTACATGCATAGT
GAAATTGATGCGATTGAAAGAAATCACATCATCCGCTCTTTAAGGCTTAAAGAATTTGACATTTTAATAGGGATCAATCT
TTTAAGAGAAGGGCTGGATTTGCCTGAAGTCTCTTTAGTAGCGATCATGGATGCGGATAAAGAAGGGTTTTTAAGGAGCG
AAACAAGCCTCATTCAAACCATGGGGCGAGCCGCTAGAAACGCTAATGGCAAGGTTTTATTATACGCTAAAAAAACCACT
CAAAGCATGCAAAAAGCCTTTGAAATTACAAGTTACAGGCGCGCTAAGCAAGAAGAGTTTAATAAGCTTCATCATATCAC
CCCCAAAACCGTTACTCGCACTTTAGAAGAGGAGTTGAAATTAAGAGACGATGAGATTAAAATCGCTAAAGCCTTAAAAA
AGGACAAAATCCCTAAAAGCGAAAGGGAAAAAATCATTAAAGAACTGGATAAAAAAATGCGAGAATGCGCGAAAAATTTG
GATTTTGAAGAAGCGATGCGTTTGAGAGACGAAATCGCTAAATTAAGAACGCTTTAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(623-657)

Type III restriction enzyme, res subunit (ResIII)

(15-137)

UvrB interaction domain (UvrB_inter)

(159-248)

Ultra-violet resistance protein B (UvrB)

(554-595)

Helicase conserved C-terminal domain (Helicase_C)

(445-547)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

49.623

100

0.5
  uvrB Streptococcus pneumoniae D39

49.623

100

0.5
  uvrB Streptococcus pneumoniae TIGR4

49.623

100

0.5