Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   VA211_RS01935 Genome accession   NZ_CP141771
Coordinates   378563..380539 (+) Length   658 a.a.
NCBI ID   WP_324685753.1    Uniprot ID   -
Organism   Helicobacter pylori strain P08204     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 373563..385539
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VA211_RS01920 ggt 374191..375894 (+) 1704 WP_001254520.1 gamma-glutamyltransferase -
  VA211_RS01925 - 376179..376949 (+) 771 WP_324686356.1 HP1117 family Sel1-like repeat protein -
  VA211_RS01930 - 377363..378493 (+) 1131 WP_324685751.1 DUF3519 domain-containing protein -
  VA211_RS01935 uvrB 378563..380539 (+) 1977 WP_324685753.1 excinuclease ABC subunit UvrB Machinery gene
  VA211_RS01940 - 380536..381369 (-) 834 WP_324685754.1 outer membrane protein -
  VA211_RS01945 purB 381434..382756 (-) 1323 WP_324685755.1 adenylosuccinate lyase -
  VA211_RS01950 - 382866..383810 (-) 945 WP_000238169.1 thiamine pyrophosphate-dependent enzyme -
  VA211_RS01955 - 383823..385046 (-) 1224 WP_324685758.1 2-oxoacid:ferredoxin oxidoreductase subunit alpha -
  VA211_RS01960 - 385056..385448 (-) 393 WP_000656168.1 4Fe-4S dicluster-binding protein -

Sequence

Protein


Download         Length: 658 a.a.        Molecular weight: 75824.26 Da        Isoelectric Point: 6.7306

>NTDB_id=837783 VA211_RS01935 WP_324685753.1 378563..380539(+) (uvrB) [Helicobacter pylori strain P08204]
MPLFDLKSPYPPAGDQPQAIEALTKSLKNNNHYQTLVGVTGSGKTYTMANIIANTNKPTLIMSHNKTLCAQLYSEFKAFF
PHNRVEYFISHFDYYQPESYIPRRDLFIEKDSSINDDLERLRLSAATSLLGYDDVIVIASVSANYGLGNPEEYLKVMEKI
KVGEKRVYKGFLLKLVEMGYSRNEVVFDRGSFRATGECVDIFPAYNDAEFIRIEFFGDEIERIAVFDALERNEIKRLDSV
MLYAASQFAVGSERLNLAIKSIEDELALRLKFFKEQDKMLEYNRLKQRTEHDLEMISATGVCKGIENYARHFTGKAPNET
PFCLFDYLGIFGREFLVIVDESHVSLPQFGGMYAGDMSRKSVLVEYGFRLPSALDNRPLKFDEFIHKNCQFLFVSATPNK
LELELSKENVAEQIIRPTGLLDPKFEVRDSDKQVQDLFDEIKLVVARNERVLITTLTKKMAEELCKYYAEWGLKARYMHS
EIDAIERNHIIRSLRLKEFDILIGINLLREGLDLPEVSLVAIMDADKEGFLRSETSLIQTMGRAARNANGKVLLYAKKIT
QSMQKAFEITSYRRAKQEEFNKLHNITPKTVTRALEEELKLRDDEVKIAKALKKDKIPKSEREKIIKELDKKMRECAKNL
DFEEAMRLRDEIAQLRTL

Nucleotide


Download         Length: 1977 bp        

>NTDB_id=837783 VA211_RS01935 WP_324685753.1 378563..380539(+) (uvrB) [Helicobacter pylori strain P08204]
ATGCCTTTATTTGATTTAAAAAGCCCTTACCCACCAGCAGGCGATCAGCCCCAAGCCATAGAAGCCTTAACGAAAAGCTT
GAAAAATAACAACCATTATCAAACTTTAGTGGGGGTTACAGGGAGCGGTAAGACTTATACGATGGCCAATATCATCGCTA
ATACCAACAAACCCACTCTGATCATGAGCCATAATAAGACCTTATGCGCGCAGCTCTATAGCGAATTTAAGGCGTTTTTC
CCGCATAATAGGGTGGAGTATTTCATCTCCCACTTTGACTACTACCAGCCTGAAAGCTATATCCCTAGAAGGGATTTATT
CATTGAAAAAGACAGCTCTATTAATGATGATTTAGAGCGTTTGAGGTTGAGCGCGGCCACCTCACTTTTAGGTTATGATG
ATGTGATCGTGATAGCGAGCGTTTCGGCTAATTATGGTTTGGGTAACCCTGAAGAATATTTAAAAGTCATGGAAAAAATC
AAAGTGGGCGAGAAGCGCGTTTATAAGGGCTTTTTACTCAAGCTAGTAGAAATGGGTTATAGCCGTAATGAAGTGGTGTT
TGATAGAGGGAGCTTCAGGGCGACCGGAGAATGCGTGGATATTTTTCCCGCTTATAATGACGCTGAATTTATTAGGATTG
AATTTTTTGGCGATGAGATAGAAAGGATTGCTGTCTTTGACGCTTTAGAAAGAAATGAAATCAAGCGATTGGATTCTGTC
ATGCTTTATGCGGCCAGTCAGTTTGCGGTGGGGAGTGAGAGGTTGAATTTAGCCATTAAAAGCATTGAAGATGAACTCGC
TTTAAGATTGAAATTTTTTAAAGAGCAGGATAAAATGCTTGAATACAACCGCCTCAAACAACGCACCGAGCATGATTTAG
AAATGATTAGCGCAACCGGTGTGTGTAAGGGCATTGAAAATTACGCGCGCCATTTTACAGGCAAAGCCCCCAATGAAACG
CCTTTTTGTTTGTTTGATTATTTAGGGATATTTGGGCGGGAGTTTTTAGTCATTGTGGATGAAAGCCATGTGAGTTTGCC
GCAGTTTGGGGGGATGTATGCAGGGGATATGAGCAGGAAAAGCGTTTTAGTGGAATATGGTTTTAGATTGCCTAGCGCTT
TAGACAACCGCCCTTTAAAATTTGATGAATTTATCCATAAAAATTGCCAGTTCCTTTTTGTGTCCGCCACGCCCAATAAG
CTAGAATTAGAGCTTTCTAAAGAGAATGTTGCTGAGCAAATCATTCGCCCTACAGGGCTTTTAGACCCTAAATTTGAAGT
GCGAGACAGCGATAAGCAAGTCCAGGATTTATTTGATGAAATCAAGTTAGTGGTGGCTAGAAATGAAAGGGTGCTTATCA
CCACGCTCACTAAAAAAATGGCAGAAGAATTGTGCAAATATTATGCTGAATGGGGCTTGAAAGCGCGTTACATGCATAGT
GAAATTGATGCGATTGAAAGGAATCACATCATCCGTTCTTTAAGGCTTAAAGAATTTGACATTTTAATAGGGATCAATCT
TTTAAGAGAAGGGCTGGATTTGCCTGAAGTCTCTTTAGTAGCGATCATGGATGCGGATAAAGAAGGGTTTTTAAGGAGTG
AAACAAGCCTCATTCAAACCATGGGGCGAGCCGCTAGAAACGCTAATGGCAAGGTTTTATTATACGCTAAAAAAATCACC
CAAAGCATGCAAAAAGCCTTTGAAATTACGAGCTACAGGCGTGCTAAGCAAGAAGAGTTTAATAAGCTTCACAATATCAC
CCCCAAAACCGTTACTCGCGCTTTAGAAGAGGAGTTGAAATTAAGAGACGATGAGGTTAAAATCGCTAAAGCCTTAAAAA
AAGACAAAATCCCTAAAAGTGAAAGGGAAAAAATCATTAAAGAACTGGATAAAAAAATGCGAGAATGTGCGAAAAATTTG
GATTTTGAAGAAGCGATGCGTTTGAGAGACGAAATCGCTCAATTAAGAACGCTTTAA

Domains

Predicted by InterProScan.

Type III restriction enzyme, res subunit (ResIII)

(15-123)

UvrB/uvrC motif (UVR)

(623-657)

Helicase conserved C-terminal domain (Helicase_C)

(445-547)

UvrB interaction domain (UvrB_inter)

(160-248)

Ultra-violet resistance protein B (UvrB)

(554-595)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

49.623

100

0.5
  uvrB Streptococcus pneumoniae D39

49.623

100

0.5
  uvrB Streptococcus pneumoniae TIGR4

49.623

100

0.5