Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   VA249_RS13170 Genome accession   NZ_AP024165
Coordinates   2857725..2858357 (+) Length   210 a.a.
NCBI ID   WP_005381432.1    Uniprot ID   U2ZZI4
Organism   Vibrio alfacsensis strain 04Ya108     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2852725..2863357
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VA249_RS13145 (VYA_24700) - 2852730..2854649 (+) 1920 WP_211915837.1 ABC transporter ATP-binding protein -
  VA249_RS13150 (VYA_24710) - 2854646..2855125 (+) 480 WP_128809985.1 TIGR02444 family protein -
  VA249_RS13155 (VYA_24720) - 2855226..2856227 (+) 1002 WP_128809984.1 hydrolase -
  VA249_RS13160 (VYA_24730) - 2856276..2856488 (+) 213 WP_128809983.1 YheU family protein -
  VA249_RS13165 (VYA_24740) - 2856616..2857485 (+) 870 WP_128812224.1 phosphoribulokinase -
  VA249_RS13170 (VYA_24750) crp 2857725..2858357 (+) 633 WP_005381432.1 cAMP-activated global transcriptional regulator CRP Regulator
  VA249_RS13175 (VYA_24760) - 2858459..2859253 (-) 795 WP_221068238.1 DUF1338 domain-containing protein -
  VA249_RS13180 (VYA_24770) astD 2859515..2860972 (-) 1458 WP_221068239.1 succinylglutamate-semialdehyde dehydrogenase -
  VA249_RS13185 (VYA_24780) astA 2861001..2862020 (-) 1020 WP_221068240.1 arginine N-succinyltransferase -
  VA249_RS13190 (VYA_24790) - 2862130..2863341 (-) 1212 WP_128809980.1 aspartate aminotransferase family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23665.48 Da        Isoelectric Point: 7.8388

>NTDB_id=83746 VA249_RS13170 WP_005381432.1 2857725..2858357(+) (crp) [Vibrio alfacsensis strain 04Ya108]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHAGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEED
QERTAWVRAKSPCEVAEISFKKFRQLIQVNPDILMRLSAQMARRLQVTSQKVGDLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEEQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=83746 VA249_RS13170 WP_005381432.1 2857725..2858357(+) (crp) [Vibrio alfacsensis strain 04Ya108]
ATGGTTCTAGGTAAACCTCAAACCGACCCAACATTAGAATGGTTTCTTTCACACTGTCACATTCATAAGTACCCATCAAA
AAGCACGCTAATTCACGCGGGCGAAAAAGCAGAAACTTTGTACTACATCGTTAAAGGTTCTGTTGCGGTTCTTATCAAGG
ACGAAGAAGGTAAGGAGATGATCCTTTCTTACCTAAACCAAGGTGACTTCATTGGTGAGCTTGGCCTATTCGAAGAAGAC
CAAGAGCGTACAGCTTGGGTTCGTGCTAAATCTCCTTGTGAAGTGGCAGAAATTTCTTTCAAGAAGTTCCGTCAACTTAT
CCAAGTAAACCCAGATATCCTTATGCGCCTTTCTGCGCAGATGGCTCGTCGTCTTCAAGTTACTAGCCAAAAAGTAGGTG
ACCTAGCGTTCCTAGACGTAACTGGTCGTATCGCTCAGACTCTTCTGAACCTAGCTAAACAACCAGATGCGATGACTCAC
CCAGACGGCATGCAAATCAAGATCACTCGTCAAGAAATCGGTCAAATTGTTGGCTGTTCTCGTGAAACCGTTGGTCGTAT
CTTGAAAATGCTAGAAGAACAAAACCTAATCTCTGCACACGGTAAAACTATCGTTGTATACGGGACTCGTTAA

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB U2ZZI4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

98.095

100

0.981
  crp Haemophilus influenzae Rd KW20

75.49

97.143

0.733
  crp Acinetobacter baumannii D1279779

47.826

98.571

0.471

Multiple sequence alignment