Detailed information NTG0833434

Bioinformatically predicted

Overview

• Name: uvrB
• Type: Machinery gene
• Locus tag: U2W44_RS05435
• Genome accession: NZ_CP140114
• Coordinates: 1069542..1071533 (-)
• Length: 663 a.a.
• NCBI ID: WP_002984194.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NV6
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1064542..1076533

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
U2W44_RS05410 (U2W44_05410)	dltD	1064832..1066082 (-)	1251	WP_002984219.1	D-alanyl-lipoteichoic acid biosynthesis protein DltD	-
U2W44_RS05415 (U2W44_05415)	dltC	1066075..1066314 (-)	240	WP_002984216.1	D-alanine--poly(phosphoribitol) ligase subunit DltC	-
U2W44_RS05420 (U2W44_05420)	dltB	1066332..1067588 (-)	1257	WP_010922392.1	D-alanyl-lipoteichoic acid biosynthesis protein DltB	-
U2W44_RS05425 (U2W44_05425)	dltA	1067585..1069123 (-)	1539	WP_002989572.1	D-alanine--poly(phosphoribitol) ligase subunit DltA	-
U2W44_RS05430 (U2W44_05430)	-	1069135..1069278 (-)	144	WP_002984200.1	teichoic acid D-Ala incorporation-associated protein DltX	-
U2W44_RS05435 (U2W44_05435)	uvrB	1069542..1071533 (-)	1992	WP_002984194.1	excinuclease ABC subunit UvrB	Machinery gene
U2W44_RS05440 (U2W44_05440)	-	1071726..1073900 (+)	2175	WP_011285590.1	ABC transporter substrate-binding protein/permease	-
U2W44_RS05445 (U2W44_05445)	-	1073900..1074640 (+)	741	WP_002984187.1	amino acid ABC transporter ATP-binding protein	-
U2W44_RS05450 (U2W44_05450)	-	1074788..1074940 (-)	153	WP_003062002.1	hypothetical protein	-
U2W44_RS05455 (U2W44_05455)	-	1074937..1076316 (-)	1380	WP_047343327.1	PTS sugar transporter subunit IIC	-

Sequence

Protein

• Length: 663 a.a.
• Molecular weight: 75654.68 Da
• Isoelectric Point: 4.6420

>NTDB_id=833434 U2W44_RS05435 WP_002984194.1 1069542..1071533(-) (uvrB) [Streptococcus pyogenes strain NV6]
MIDKRDDKPFKLKSKYKPSGDQPQAIESLVDNIEGGEKAQILLGATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYG
EFKEFFPDNAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEYA
DSAVSLRPGQEISRDTLLNQLVDIQFERNDIDFQRGCFRVRGDVVEVFPASRDEHAFRVEFFGDEIDRICEIESLTGKTI
GEVDHLVLFPATHFVTNDEHMEQSIAKIQAELAEQLQLFESEGKLLEAQRLRQRTEYDIEMLREMGYTSGVENYSRHMDG
RSPGEPPYTLLDFFPEDFLIMIDESHMTMGQIKGMYNGDQARKQMLVDYGFRLPSALDNRPLRREEFESHVHQIVYVSAT
PGEYEMSQTNTIIEQIIRPTGLLDPEIDVRSSMGQMDDLLGEINQRVARDERTFITTLTKKMAEDLTDYLKEMGVKVKYM
HSDIKTLERTEIIRDLRLGVFDVLIGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNVDGHVIMYADK
MTDSMQRAIDETARRREIQIAYNKAHGIVPQTIKKDIRGLISISKTSHNDISKEEMDYESMSRGERKEAINALQKQMQEA
AELLDFELAAQMRDLILELKLMD

Nucleotide

• Length: 1992 bp

>NTDB_id=833434 U2W44_RS05435 WP_002984194.1 1069542..1071533(-) (uvrB) [Streptococcus pyogenes strain NV6]
ATGATTGATAAACGTGATGATAAACCATTTAAACTAAAATCAAAGTATAAACCGTCTGGTGATCAGCCACAAGCTATTGA
AAGCCTAGTTGATAATATCGAGGGCGGAGAAAAAGCTCAGATTCTCCTAGGTGCTACAGGAACGGGAAAAACATACACCA
TGAGCCAAGTAATTAGTAAAGTAAATAAACCTACCTTAGTGATAGCTCACAATAAAACCTTAGCAGGACAATTATATGGT
GAATTTAAAGAATTTTTTCCAGACAATGCTGTGGAATATTTTGTTTCCTATTATGATTACTACCAACCTGAAGCATATGT
CCCATCAAGCGACACCTATATCGAAAAAGATAGTTCAGTCAATGATGAAATCGATAAACTTCGCCATTCAGCCACCTCTT
CTTTACTTGAGCGTAACGATGTCATAGTGGTAGCTTCTGTATCTTGTATTTATGGACTAGGTTCGCCAAAAGAGTACGCA
GATTCAGCAGTCAGCCTACGTCCAGGTCAGGAGATATCACGTGACACTTTGCTAAATCAATTAGTAGATATTCAATTTGA
GCGTAATGATATTGATTTTCAACGCGGCTGTTTTCGTGTACGTGGCGATGTTGTTGAGGTCTTTCCAGCATCCAGGGATG
AACATGCTTTTCGGGTGGAATTTTTCGGGGATGAGATTGACCGTATATGTGAAATCGAAAGTTTAACTGGTAAAACTATT
GGAGAAGTTGACCATTTGGTTTTATTTCCAGCTACTCACTTTGTAACAAATGATGAGCATATGGAGCAATCAATAGCCAA
AATTCAAGCAGAGTTAGCAGAGCAGTTACAGTTATTTGAATCTGAAGGTAAACTACTAGAAGCACAGCGATTACGCCAAA
GAACGGAATATGATATTGAAATGTTACGTGAAATGGGCTATACTAGCGGAGTCGAAAACTATTCCCGTCATATGGATGGC
AGGTCACCAGGAGAACCTCCTTATACCTTGTTAGATTTCTTCCCAGAAGATTTTTTAATTATGATTGATGAAAGTCACAT
GACAATGGGACAAATCAAAGGCATGTATAATGGTGACCAAGCCAGAAAACAAATGCTAGTTGACTATGGTTTTCGATTGC
CATCAGCTCTTGATAATCGTCCCTTAAGACGCGAGGAATTTGAAAGTCATGTGCACCAAATTGTCTATGTTTCAGCAACG
CCTGGTGAATACGAAATGTCACAGACTAATACAATTATTGAGCAAATTATTCGTCCGACTGGGCTACTTGATCCTGAAAT
TGATGTAAGGTCAAGTATGGGGCAAATGGATGATTTGTTGGGAGAAATTAACCAGCGCGTAGCGCGCGATGAACGGACGT
TCATCACAACCTTAACTAAAAAAATGGCAGAAGATTTGACTGATTATCTAAAAGAGATGGGTGTCAAGGTCAAGTATATG
CACAGTGATATTAAAACCTTAGAGCGAACAGAAATTATTCGTGATTTACGACTTGGTGTTTTTGATGTCTTGATTGGAAT
CAATCTGCTCCGTGAAGGGATTGATGTGCCAGAAGTTAGTCTTGTAGCCATTTTGGATGCTGATAAAGAGGGTTTCCTCC
GTAATGAACGCGGCTTGATTCAGACCATCGGTAGAGCAGCTCGAAACGTAGATGGTCATGTCATTATGTATGCGGACAAG
ATGACAGATTCTATGCAGCGAGCTATTGACGAAACGGCTCGTCGTCGTGAGATTCAAATAGCATATAACAAAGCGCACGG
CATCGTTCCACAAACTATAAAAAAAGACATCAGAGGCCTTATTAGTATAAGTAAAACAAGCCACAATGATATATCAAAAG
AAGAGATGGATTATGAAAGTATGTCAAGAGGAGAACGAAAAGAAGCGATCAATGCTCTGCAAAAACAAATGCAAGAGGCA
GCTGAATTACTTGATTTCGAATTGGCAGCTCAAATGCGAGACTTGATTTTAGAACTTAAATTAATGGACTAG

Domains

Predicted by InterProScan.

• Ultra-violet resistance protein B (UvrB) (556-598)

• UvrB interaction domain (UvrB_inter) (164-254)

• Helicase conserved C-terminal domain (Helicase_C) (443-548)

• UvrB/uvrC motif (UVR) (627-660)

• Type III restriction enzyme, res subunit (ResIII) (17-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrB	Streptococcus pneumoniae R6	84.917	100	0.849
uvrB	Streptococcus pneumoniae D39	84.917	100	0.849
uvrB	Streptococcus pneumoniae TIGR4	84.766	100	0.848