Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   U0450_RS10260 Genome accession   NZ_CP139863
Coordinates   1983011..1984999 (+) Length   662 a.a.
NCBI ID   WP_127245060.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 15P2112     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1978011..1989999
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0450_RS10245 - 1978907..1979647 (-) 741 WP_001096313.1 amino acid ABC transporter ATP-binding protein -
  U0450_RS10250 - 1979647..1981812 (-) 2166 WP_000726258.1 ABC transporter substrate-binding protein/permease -
  U0450_RS10255 - 1981981..1982934 (+) 954 WP_127245061.1 CPBP family intramembrane glutamic endopeptidase -
  U0450_RS10260 uvrB 1983011..1984999 (+) 1989 WP_127245060.1 excinuclease ABC subunit UvrB Machinery gene
  U0450_RS10265 - 1985009..1985572 (+) 564 WP_050102484.1 GNAT family N-acetyltransferase -
  U0450_RS10270 - 1985538..1986026 (+) 489 WP_050102483.1 GNAT family N-acetyltransferase -
  U0450_RS10275 - 1986098..1986565 (+) 468 WP_050102482.1 8-oxo-dGTP diphosphatase -
  U0450_RS10280 - 1986562..1987077 (-) 516 WP_000159178.1 transcription repressor NadR -
  U0450_RS10285 - 1987089..1987616 (-) 528 WP_001097402.1 ECF transporter S component -
  U0450_RS10290 - 1987898..1988461 (-) 564 WP_000747408.1 ECF transporter S component -
  U0450_RS10295 coaC 1988445..1988996 (-) 552 WP_001284130.1 phosphopantothenoylcysteine decarboxylase -
  U0450_RS10300 coaB 1989008..1989697 (-) 690 WP_000699503.1 phosphopantothenate--cysteine ligase -

Sequence

Protein


Download         Length: 662 a.a.        Molecular weight: 75801.81 Da        Isoelectric Point: 4.5441

>NTDB_id=832491 U0450_RS10260 WP_127245060.1 1983011..1984999(+) (uvrB) [Streptococcus pneumoniae strain 15P2112]
MINRITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMGATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYG
EFKEFFPENAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFRVEFFGDEIDRIREVEALTGQVL
GEVDHLAIFPATHFVTNDDHMEVAIAKIQTELEEQLAVFENEGKLLESQRLKQRTEYDIEMLREMGYTNGVENYSRHMDG
RSEGEPPYTLLDFFPDDFLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESYVHQIVYVSAT
PGDYEGEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKNERTFITTLTKKMAEDLTDYFKEMGIKVKYM
HSDIKTLERTEIIRDLRLGVFDVLVGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADT
VTQSMQRAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKTVAKEEDKEVDINSLNKQERKELVKKLEKQMQEAV
EVLDFELAAQIRDMMLEVKALD

Nucleotide


Download         Length: 1989 bp        

>NTDB_id=832491 U0450_RS10260 WP_127245060.1 1983011..1984999(+) (uvrB) [Streptococcus pneumoniae strain 15P2112]
ATGATCAATCGCATTACAGATAATCAATTTAAACTAGTATCAAAATATCAACCTTCAGGAGACCAACCTCAAGCTATTGA
GCAGTTGGTTGATAATATCGAGGGGGGAGAAAAAGCTCAGATTCTGATGGGGGCGACCGGAACAGGGAAGACCTATACCA
TGAGTCAGGTCATTTCCAAAGTCAATAAACCAACTCTGGTTATTGCCCACAATAAAACTCTAGCAGGCCAGCTATATGGA
GAGTTTAAGGAATTTTTCCCTGAAAATGCAGTTGAGTATTTCGTATCCTACTATGATTATTACCAGCCAGAGGCCTATGT
ACCTTCTAGTGATACCTATATTGAGAAGGATAGTTCTGTCAATGATGAGATTGACAAGCTCCGCCACTCAGCGACTTCGG
CTCTTTTGGAGCGTAATGATGTTATTGTCGTGGCCTCAGTCTCTTGTATCTATGGTTTGGGTTCGCCCAAGGAATACGCT
GATAGTGTCGTTAGTCTCCGTCCAGGTCTTGAAATTTCTCGTGATAAACTCTTGAATGACTTGGTTGATATCCAGTTTGA
ACGTAATGATATTGATTTCCAACGGGGAAGATTTCGTGTTCGTGGGGATGTGGTGGAGATTTTCCCAGCATCTCGTGATG
AACACGCTTTTCGAGTAGAATTTTTTGGAGACGAAATTGACCGTATTCGTGAGGTTGAGGCCCTGACTGGTCAGGTATTG
GGAGAAGTGGATCATTTAGCGATTTTCCCAGCTACTCACTTTGTGACCAATGACGACCACATGGAAGTGGCCATTGCTAA
AATTCAGACTGAGTTGGAAGAGCAGTTAGCTGTCTTTGAGAATGAGGGCAAACTGTTAGAATCCCAGCGTTTGAAACAGC
GGACAGAGTATGATATCGAAATGTTGCGTGAGATGGGCTATACCAACGGGGTTGAGAACTATTCACGTCACATGGATGGA
CGGAGCGAAGGTGAGCCTCCTTATACGCTCTTAGATTTCTTCCCAGATGATTTCTTAATCATGATTGACGAGAGTCACAT
GACTATGGGACAAATAAAAGGCATGTACAATGGAGACCGTTCGCGTAAAGAAATGCTAGTAAATTATGGTTTCCGTTTGC
CGTCTGCTCTGGACAATCGTCCTCTCCGTCGTGAAGAATTTGAAAGCTATGTGCATCAGATTGTTTACGTTTCAGCGACA
CCAGGTGATTATGAAGGTGAACAGACTGAGACAGTGATTGAGCAAATCATTCGTCCAACAGGACTATTGGATCCAGAGGT
AGAAGTCCGTCCGACAATGGGACAGATTGATGACCTCCTAGGTGAAATCAATGCCCGTGTTGAAAAGAACGAACGGACCT
TTATTACAACCTTGACCAAGAAAATGGCAGAAGATTTGACCGACTACTTTAAGGAAATGGGCATCAAGGTCAAGTACATG
CACTCGGATATTAAGACCTTGGAACGGACGGAGATTATCCGTGACCTGCGCTTGGGTGTCTTTGATGTCTTGGTCGGAAT
TAACCTGCTCCGTGAAGGGATTGACGTTCCTGAAGTGAGCTTGGTTGCCATTCTCGATGCTGACAAGGAAGGTTTCCTAC
GTAACGAACGTGGACTCATCCAGACCATTGGCCGCGCTGCCCGTAATAGCGAAGGTCATGTCATCATGTATGCGGACACG
GTTACCCAGTCTATGCAACGTGCCATCGATGAAACTGCCCGTCGTCGCAAAATCCAGATGGCTTATAATGAAGAGCATGG
TATCGTACCACAAACCATTAAGAAAGAAATCCGTGACTTGATTGCCGTAACCAAGACTGTTGCCAAAGAAGAAGACAAGG
AAGTTGATATCAATAGTCTTAACAAACAAGAGCGCAAAGAACTGGTCAAGAAACTAGAGAAACAAATGCAAGAAGCCGTC
GAAGTGCTTGACTTTGAACTAGCAGCACAGATTCGTGATATGATGTTGGAAGTCAAGGCCTTGGATTAG

Domains

Predicted by InterProScan.

Ultra-violet resistance protein B (UvrB)

(556-598)

Type III restriction enzyme, res subunit (ResIII)

(17-143)

UvrB/uvrC motif (UVR)

(626-660)

Helicase conserved C-terminal domain (Helicase_C)

(443-549)

UvrB interaction domain (UvrB_inter)

(164-254)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

98.943

100

0.989
  uvrB Streptococcus pneumoniae D39

98.943

100

0.989
  uvrB Streptococcus pneumoniae TIGR4

98.792

100

0.988