Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   QMO72_RS04770 Genome accession   NZ_CP125718
Coordinates   1021151..1021780 (+) Length   209 a.a.
NCBI ID   WP_046837881.1    Uniprot ID   A0A1S2MGW6
Organism   Staphylococcus casei strain DSM 15096     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1016151..1026780
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QMO72_RS04740 (QMO72_04740) - 1016187..1016906 (+) 720 WP_069824827.1 glutamine amidotransferase -
  QMO72_RS04745 (QMO72_04745) - 1016999..1017985 (-) 987 WP_046837886.1 aromatic acid exporter family protein -
  QMO72_RS04750 (QMO72_04750) map 1018160..1018912 (+) 753 WP_103267997.1 type I methionyl aminopeptidase -
  QMO72_RS04755 (QMO72_04755) - 1019017..1019403 (+) 387 WP_069824825.1 hypothetical protein -
  QMO72_RS04760 (QMO72_04760) liaF 1019420..1020121 (+) 702 WP_069824824.1 cell wall-active antibiotics response protein LiaF -
  QMO72_RS04765 (QMO72_04765) vraS 1020118..1021161 (+) 1044 WP_046837882.1 sensor histidine kinase Regulator
  QMO72_RS04770 (QMO72_04770) vraR 1021151..1021780 (+) 630 WP_046837881.1 response regulator transcription factor Regulator
  QMO72_RS04775 (QMO72_04775) - 1021975..1023120 (-) 1146 WP_103267998.1 YihY/virulence factor BrkB family protein -
  QMO72_RS04780 (QMO72_04780) - 1023354..1023638 (-) 285 WP_046837879.1 hypothetical protein -
  QMO72_RS04785 (QMO72_04785) - 1023638..1024108 (-) 471 WP_103267999.1 low molecular weight protein-tyrosine-phosphatase -
  QMO72_RS04790 (QMO72_04790) - 1024242..1024448 (+) 207 WP_256121787.1 DUF1128 family protein -
  QMO72_RS04795 (QMO72_04795) - 1024464..1025705 (+) 1242 WP_103268011.1 aminopeptidase -
  QMO72_RS04800 (QMO72_04800) - 1025878..1026399 (+) 522 WP_073504123.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23702.20 Da        Isoelectric Point: 4.6181

>NTDB_id=832460 QMO72_RS04770 WP_046837881.1 1021151..1021780(+) (vraR) [Staphylococcus casei strain DSM 15096]
MPIKVLFVDDHEMVRIGISSYLSTQPDIDVVGEGKSGNEAIEKAHQLNPDLILMDLLMDDMDGVEATELIKKDLPHIKVV
MLTSYIEDNEVYRALDSGVDSYILKTTSASDIAEAIRKTYNDESVFEAEVLVKMRNRMKQRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=832460 QMO72_RS04770 WP_046837881.1 1021151..1021780(+) (vraR) [Staphylococcus casei strain DSM 15096]
ATGCCGATTAAAGTTTTATTTGTTGATGATCATGAAATGGTACGAATAGGTATTTCTAGTTATTTATCAACACAACCAGA
TATTGATGTTGTAGGAGAAGGTAAGTCAGGGAATGAAGCGATAGAAAAAGCACATCAACTTAATCCAGATTTAATCCTCA
TGGACTTACTTATGGATGATATGGATGGTGTAGAAGCTACAGAACTTATCAAAAAAGATTTACCTCATATTAAAGTGGTC
ATGTTAACAAGTTACATTGAGGATAATGAAGTATACCGCGCCTTAGATTCAGGTGTAGACAGTTATATTTTAAAAACTAC
AAGCGCAAGTGATATTGCTGAAGCAATACGTAAGACATATAATGATGAGTCTGTATTTGAAGCAGAAGTATTAGTGAAAA
TGAGAAATAGAATGAAACAACGTGCCGAGTTATATGAAATGCTTACAGAACGTGAGATGGAAATTTTATTACTTATTGCT
AAAGGATACTCGAATCAAGAAATAGCTAGTGCTTCACACATTACAATCAAAACCGTCAAGACCCATGTAAGTAATATATT
AAGTAAATTGGAAGTACAAGATAGAACACAAGCAGTTATTTATGCGTTCCAACATAATTTAATACAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-117)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1S2MGW6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

88.517

100

0.885
  degU Bacillus subtilis subsp. subtilis str. 168

33.929

100

0.364