Detailed information NTG0832459

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: QMO72_RS04765
• Genome accession: NZ_CP125718
• Coordinates: 1020118..1021161 (+)
• Length: 347 a.a.
• NCBI ID: WP_046837882.1
• Uniprot ID: A0A1S2MGQ4
• Organism: Staphylococcus casei strain DSM 15096
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1015118..1026161

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QMO72_RS04740 (QMO72_04740)	-	1016187..1016906 (+)	720	WP_069824827.1	glutamine amidotransferase	-
QMO72_RS04745 (QMO72_04745)	-	1016999..1017985 (-)	987	WP_046837886.1	aromatic acid exporter family protein	-
QMO72_RS04750 (QMO72_04750)	map	1018160..1018912 (+)	753	WP_103267997.1	type I methionyl aminopeptidase	-
QMO72_RS04755 (QMO72_04755)	-	1019017..1019403 (+)	387	WP_069824825.1	hypothetical protein	-
QMO72_RS04760 (QMO72_04760)	liaF	1019420..1020121 (+)	702	WP_069824824.1	cell wall-active antibiotics response protein LiaF	-
QMO72_RS04765 (QMO72_04765)	vraS	1020118..1021161 (+)	1044	WP_046837882.1	sensor histidine kinase	Regulator
QMO72_RS04770 (QMO72_04770)	vraR	1021151..1021780 (+)	630	WP_046837881.1	response regulator transcription factor	Regulator
QMO72_RS04775 (QMO72_04775)	-	1021975..1023120 (-)	1146	WP_103267998.1	YihY/virulence factor BrkB family protein	-
QMO72_RS04780 (QMO72_04780)	-	1023354..1023638 (-)	285	WP_046837879.1	hypothetical protein	-
QMO72_RS04785 (QMO72_04785)	-	1023638..1024108 (-)	471	WP_103267999.1	low molecular weight protein-tyrosine-phosphatase	-
QMO72_RS04790 (QMO72_04790)	-	1024242..1024448 (+)	207	WP_256121787.1	DUF1128 family protein	-
QMO72_RS04795 (QMO72_04795)	-	1024464..1025705 (+)	1242	WP_103268011.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40023.42 Da
• Isoelectric Point: 6.2448

>NTDB_id=832459 QMO72_RS04765 WP_046837882.1 1020118..1021161(+) (vraS) [Staphylococcus casei strain DSM 15096]
MNHYLRAIGSMLILVYSTFFAIFFIDKVFVNIMYFQGMFYTQIFGIPVLLFLNLLVILLCIIVGSVLAYKINQQNHWLQE
QIERSIEGQTVGINDQNIELYNETIELYQTLVPLNQEVHKLRMKTQNLTNESYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESQLEAPLDQQIPVLEKMIQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVVDLQKKVPMKVVHDI
EEFKVPKGIEDHLFRITQEAISNTLRHSKGTKVTIELFNRTDYLLLRIQDNGKGFNVDEKAEQSYGLKNMRERALEIGAT
YHIVSLPDSGTRIEVKAPLNKEDSYAD

Nucleotide

• Length: 1044 bp

>NTDB_id=832459 QMO72_RS04765 WP_046837882.1 1020118..1021161(+) (vraS) [Staphylococcus casei strain DSM 15096]
ATGAATCACTACTTAAGGGCAATAGGATCCATGTTAATTTTAGTCTATAGTACATTTTTCGCGATATTCTTTATTGATAA
AGTCTTTGTAAACATCATGTACTTTCAAGGTATGTTTTATACACAAATATTTGGAATACCAGTTTTACTATTTTTAAATT
TATTGGTTATATTGCTCTGTATTATAGTAGGATCAGTATTAGCATATAAAATTAATCAACAGAACCATTGGTTACAAGAA
CAAATTGAACGTTCTATAGAAGGTCAAACTGTAGGGATTAATGATCAAAATATAGAGTTGTATAATGAAACGATAGAATT
ATATCAAACACTTGTACCTTTAAATCAAGAAGTGCACAAATTAAGAATGAAAACACAAAATTTAACGAATGAATCTTATA
ATATTAATGATGTAAAAGTTAAAAAGATTATAGAAGATGAACGACAAAGACTAGCACGTGAATTACATGATTCTGTAAGC
CAACAATTATTTGCCGCAAGTATGATGCTTTCTGCTATCAAAGAATCCCAATTAGAAGCACCTTTGGATCAACAAATCCC
AGTACTTGAAAAGATGATACAAGACTCTCAATTAGAGATGAGAGCACTACTATTACACTTAAGACCACTGGGCTTAAAAG
ATAAATCGTTAGGTGAAGGGATTAAAGATTTAGTTGTAGACCTCCAGAAAAAAGTGCCAATGAAAGTTGTCCATGATATC
GAAGAGTTTAAAGTACCAAAGGGTATTGAAGATCATTTATTTAGAATCACACAAGAAGCAATTTCCAATACTTTGAGACA
TTCTAAGGGCACTAAGGTTACGATTGAATTGTTTAATAGAACAGATTATTTACTATTGCGTATACAAGATAATGGTAAAG
GATTTAATGTAGATGAGAAGGCTGAACAAAGTTATGGGTTGAAAAATATGAGAGAACGCGCATTGGAAATTGGCGCTACA
TATCATATTGTATCTTTACCAGACTCAGGAACAAGAATAGAAGTTAAGGCACCATTAAATAAGGAGGATTCATATGCCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

3D structure

• AlphaFold DB: A0A1S2MGQ4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	88.184	100	0.882