Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   U0449_RS08315 Genome accession   NZ_CP139862
Coordinates   1615539..1616216 (+) Length   225 a.a.
NCBI ID   WP_000548964.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 05H0020-2     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1610539..1621216
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0449_RS08285 - 1610907..1611614 (-) 708 WP_322397623.1 nicotinamide mononucleotide transporter -
  U0449_RS08290 - 1611732..1612382 (-) 651 WP_000188505.1 metal-dependent transcriptional regulator -
  U0449_RS08295 - 1612494..1613336 (+) 843 WP_000160934.1 metallophosphoesterase -
  U0449_RS08300 - 1613412..1613849 (+) 438 WP_001166786.1 Rrf2 family transcriptional regulator -
  U0449_RS08305 - 1613917..1614219 (+) 303 WP_000281608.1 hypothetical protein -
  U0449_RS08310 - 1614310..1615383 (-) 1074 WP_001273814.1 DUF2974 domain-containing protein -
  U0449_RS08315 braR 1615539..1616216 (+) 678 WP_000548964.1 response regulator transcription factor Regulator
  U0449_RS08320 - 1616209..1617183 (+) 975 WP_000887958.1 HAMP domain-containing histidine kinase -
  U0449_RS08325 thrS 1617232..1619175 (-) 1944 WP_000608353.1 threonine--tRNA ligase -
  U0449_RS08330 - 1619233..1619409 (-) 177 WP_000166031.1 MazG-like protein -
  U0449_RS08335 - 1619416..1619556 (-) 141 WP_000422775.1 MazG-like protein -
  U0449_RS08340 - 1619813..1620187 (-) 375 Protein_1601 hypothetical protein -
  U0449_RS08345 - 1620426..1621055 (+) 630 WP_001864883.1 NAD(P)-dependent oxidoreductase -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25949.19 Da        Isoelectric Point: 5.6311

>NTDB_id=832361 U0449_RS08315 WP_000548964.1 1615539..1616216(+) (braR) [Streptococcus pneumoniae strain 05H0020-2]
MHKILLIEDDQVIRQQVGKMLSEWGFEVVLVEDFMKVLSLFVQSEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide


Download         Length: 678 bp        

>NTDB_id=832361 U0449_RS08315 WP_000548964.1 1615539..1616216(+) (braR) [Streptococcus pneumoniae strain 05H0020-2]
ATGCACAAGATTTTATTAATAGAAGATGATCAGGTCATTCGTCAACAGGTCGGGAAAATGCTCTCTGAATGGGGATTTGA
AGTGGTCCTGGTAGAAGACTTTATGAAAGTTTTGAGTCTATTTGTTCAGTCGGAACCTCATCTGGTCCTCATGGATATTG
GTTTGCCCTTGTTTAATGGTTATCACTGGTGTCAGGAAATCCGCAAGATTTCCAAGGTACCTATCATGTTTCTTTCTTCG
AGAGACCAGGCTATGGATATTGTCATGGCAATCAATATGGGGGCAGATGACTTTGTGACCAAGCCTTTTGACCAGCAGGT
TCTTTTAGCCAAGGTTCAGGGCTTGTTGCGTCGTTCCTATGAGTTTGGGCGTGATGAGAGTTTGCTGGAATATGCTGGTG
TTATCCTCAATACCAAATCCATGGATTTACATTATCAAGGGCAAGTCTTGAATTTGACCAAGAACGAATTCCAGATTTTA
CGCGTGTTATTTGAGCATGCAGGCAACATCGTAGCACGTGACGATCTGATGCGAGAACTTTGGAACAGTGACTTTTTCAT
TGATGATAATACCCTCTCTGTCAATGTGGCTCGTTTGCGTAAAAAGTTGGAGGAGCAGGGATTGGTAGGATTTATCGAGA
CCAAGAAAGGAATAGGGTACGGATTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

48.624

96.889

0.471