Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   U0448_RS04615 Genome accession   NZ_CP139860
Coordinates   891143..891637 (-) Length   164 a.a.
NCBI ID   WP_224757304.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 21011     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 886143..896637
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0448_RS04585 - 886443..887318 (+) 876 WP_050258944.1 substrate-binding domain-containing protein -
  U0448_RS04590 pstC 887436..888299 (+) 864 WP_000165892.1 phosphate ABC transporter permease subunit PstC -
  U0448_RS04595 pstA 888292..889107 (+) 816 WP_000049768.1 phosphate ABC transporter permease PstA -
  U0448_RS04600 pstB 889109..889861 (+) 753 WP_000536449.1 phosphate ABC transporter ATP-binding protein PstB -
  U0448_RS04605 phoU 889876..890526 (+) 651 WP_001245781.1 phosphate signaling complex protein PhoU -
  U0448_RS04610 - 890603..891028 (+) 426 Protein_864 transposase -
  U0448_RS04615 comR 891143..891637 (-) 495 WP_224757304.1 helix-turn-helix transcriptional regulator Regulator
  U0448_RS04620 - 891795..892811 (+) 1017 WP_000415108.1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase -
  U0448_RS04625 galU 892833..893732 (+) 900 WP_000202227.1 UTP--glucose-1-phosphate uridylyltransferase GalU -
  U0448_RS04630 - 893799..894476 (-) 678 WP_000658494.1 rhomboid family intramembrane serine protease -
  U0448_RS04635 - 894460..894999 (-) 540 WP_000834343.1 5-formyltetrahydrofolate cyclo-ligase -
  U0448_RS04640 - 895011..896141 (-) 1131 WP_000885100.1 N-acetyldiaminopimelate deacetylase -

Sequence

Protein


Download         Length: 164 a.a.        Molecular weight: 19810.88 Da        Isoelectric Point: 4.8839

>NTDB_id=832083 U0448_RS04615 WP_224757304.1 891143..891637(-) (comR) [Streptococcus pneumoniae strain 21011]
MIQYMLIIEVNNSGSSCRLREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRPILTKLKYIAERLEVEDYK
LMPSYIELDKEYLELKYFLMRTPTYEDETITQKKESVFDKIFEEYYDRLPEEERFIIPNYSYLALTNYTVQKLPEKLVEI
LSFW

Nucleotide


Download         Length: 495 bp        

>NTDB_id=832083 U0448_RS04615 WP_224757304.1 891143..891637(-) (comR) [Streptococcus pneumoniae strain 21011]
TTGATTCAGTATATGCTTATAATAGAGGTAAACAACTCAGGAAGTTCTTGTAGGTTGCGAGAGTTTGGCGAAAAAATTAA
AAGATTACGTTTGGCTAAAAAAATCAGTCGTTCAGAATTTTGTGGTGATGAGTCTGAATTAAGTATCCGTCAATTAATTA
GAATTGAAAATGGAGAATCCAGACCAATACTAACAAAGTTAAAATATATTGCTGAACGTTTGGAGGTTGAAGATTACAAG
TTGATGCCAAGTTATATAGAGTTGGATAAGGAATACCTAGAATTGAAGTATTTCTTGATGAGGACTCCTACATACGAAGA
TGAAACTATCACCCAAAAGAAAGAGAGTGTTTTTGATAAGATTTTTGAAGAGTATTATGATAGGCTACCTGAGGAAGAAA
GATTTATCATCCCAAATTATTCATATCTGGCACTAACGAACTACACAGTTCAAAAATTACCAGAAAAGCTAGTTGAAATA
CTGTCCTTCTGGTGA

Domains

Predicted by InterProScan.

ComR tetratricopeptide (ComR_TPR)

(90-137)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus pyogenes MGAS8232

55.833

73.171

0.409
  comR Streptococcus pyogenes MGAS315

54.167

73.171

0.396
  comR Streptococcus mutans UA159

52.5

73.171

0.384