Detailed information NTG0083088

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: R8623_RS09375
• Genome accession: NZ_AP026928
• Coordinates: 1819984..1820883 (-)
• Length: 299 a.a.
• NCBI ID: WP_024477664.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900700406
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1814984..1825883

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8623_RS09350 (PC0401_18150)	rsmA	1815209..1816081 (-)	873	WP_001216852.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
R8623_RS09355 (PC0401_18160)	-	1816332..1816625 (-)	294	WP_000333255.1	hypothetical protein	-
R8623_RS09360 (PC0401_18170)	-	1816618..1817259 (-)	642	WP_000565531.1	ABC transporter ATP-binding protein	-
R8623_RS09365 (PC0401_18180)	-	1817261..1819291 (-)	2031	WP_024477663.1	bacteriocin-associated integral membrane family protein	-
R8623_RS09370 (PC0401_18190)	-	1819368..1819664 (-)	297	WP_000815392.1	lactococcin 972 family bacteriocin	-
R8623_RS09375 (PC0401_18200)	comR	1819984..1820883 (-)	900	WP_024477664.1	helix-turn-helix transcriptional regulator	Regulator
R8623_RS09380 (PC0401_18210)	rnmV	1820955..1821515 (-)	561	WP_024477665.1	ribonuclease M5	-
R8623_RS09385 (PC0401_18220)	-	1821515..1822288 (-)	774	WP_024477666.1	TatD family hydrolase	-
R8623_RS09390 (PC0401_18230)	-	1822593..1823312 (-)	720	Protein_1836	DUF1542 domain-containing protein	-
R8623_RS09395 (PC0401_18240)	rpmH	1823521..1823655 (-)	135	WP_000831905.1	50S ribosomal protein L34	-
R8623_RS09400 (PC0401_18250)	-	1823800..1825014 (-)	1215	WP_000666469.1	pyridoxal phosphate-dependent aminotransferase	-
R8623_RS09405 (PC0401_18260)	-	1825170..1825463 (-)	294	WP_000977366.1	hypothetical protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35337.14 Da
• Isoelectric Point: 4.9064

>NTDB_id=83088 R8623_RS09375 WP_024477664.1 1819984..1820883(-) (comR) [Streptococcus pneumoniae strain PZ900700406]
MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPSLPKLDYIARRLGVPVYSLMPDFSALPPAYLELKYQI
LREPIYGKEEEYDKKEACLEEIYKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMSQIIEKEVYSTNDMLL
IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDY
QKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAKLIGDGFLVKKLTEEWQEDVKKYL

Nucleotide

• Length: 900 bp

>NTDB_id=83088 R8623_RS09375 WP_024477664.1 1819984..1820883(-) (comR) [Streptococcus pneumoniae strain PZ900700406]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAATTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGA
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGACTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTCCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTACGATAAGAAGGAAGCGTGTTTGGAAGAGATTTATAAAACATACTT
TGATAATCTTCCTAAAGAAGAACAATTAGCATGTGAAGTATTGCAGGCGTGTTTGGATACTTCTAGAACTAGAAGGCCTG
AATATGCAGAGTTAATACTTGAGGAACATATGTCTCAGATCATAGAAAAAGAAGTTTATTCAACAAATGATATGTTGTTG
ATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAAAGCTAATGCTCTT
TCTTTTGGAACAGAAAAAGGTAACTAAATTAGAAAACTTCTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTGTC
TTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCGTGTTTACAAGAAATTATGGATAAAACTCAAGATTAT
CAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGAAGAAAGAGATTTTAGTTTAGCTGAATCATT
TTATCAGTCTTCTAAAACATTTGCGAAGCTAATTGGAGATGGATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGAGG
ATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (70-291)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus suis P1/7	37.801	97.324	0.368
comR	Streptococcus suis 05ZYH33	37.801	97.324	0.368
comR	Streptococcus mutans UA159	37.415	98.328	0.368
comR	Streptococcus pyogenes MGAS8232	36.242	99.666	0.361