Detailed information NTG0829418

Bioinformatically predicted

Overview

• Name: uvrB
• Type: Machinery gene
• Locus tag: SKB18_RS01145
• Genome accession: NZ_CP139163
• Coordinates: 227972..229957 (-)
• Length: 661 a.a.
• NCBI ID: WP_012028187.1
• Uniprot ID: A0A0H3N3Z6
• Organism: Streptococcus suis strain cnzyss2-311
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 222972..234957

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SKB18_RS10365	-	225993..226091 (-)	99	Protein_224	UvrB/UvrC motif-containing protein	-
SKB18_RS01140	-	226134..227957 (-)	1824	WP_014636397.1	DUF2971 domain-containing protein	-
SKB18_RS01145	uvrB	227972..229957 (-)	1986	WP_012028187.1	excinuclease ABC subunit UvrB	Machinery gene
SKB18_RS01150	-	230155..232353 (+)	2199	WP_012775143.1	ABC transporter substrate-binding protein/permease	-
SKB18_RS01155	-	232353..233093 (+)	741	WP_002940438.1	amino acid ABC transporter ATP-binding protein	-
SKB18_RS01160	-	233347..233838 (-)	492	WP_011922516.1	GNAT family N-acetyltransferase	-

Sequence

Protein

• Length: 661 a.a.
• Molecular weight: 75592.64 Da
• Isoelectric Point: 4.5993

>NTDB_id=829418 SKB18_RS01145 WP_012028187.1 227972..229957(-) (uvrB) [Streptococcus suis strain cnzyss2-311]
MINRNTENQFKLVSKYAPSGDQPQAIETLVDNIEGGEKAQILMGATGTGKTYTMSQVIARVNKPTLVIAHNKTLAGQLYS
EFKEFFPENAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYS
DSVVSLRPGQEISRDQLLNALVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFRVEFFGDEIDRIREIESLTGKVL
GDVDHLAIFPATHFVTNDDHMETAIAKIQAELEEQLKVFEAEGKLLEAQRLKQRTDYDIEMLREMGYTNGVENYSRHMDG
RSEGEPPYTLLDFFPEDYLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVHQIVYVSAT
PGDYEMEQTETVVEQIIRPTGLLDPEVEVRPTMGQMDDLLGEINARVEKGERTFITTLTKKMAEDLTDYLKEMGVKVKYM
HSDIKTLERTEIIRDLRLGVFDVLIGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADK
VTESMRKAMEETARRRQIQMAYNEEHGIIPQTIKKEIRDLISVTKAVTQDKEEVVDFNALNKDERKAMIKKLEGQMQEAA
EVLDFELAAQIRDMVIELKNM

Nucleotide

• Length: 1986 bp

>NTDB_id=829418 SKB18_RS01145 WP_012028187.1 227972..229957(-) (uvrB) [Streptococcus suis strain cnzyss2-311]
ATGATCAATCGAAATACTGAAAACCAATTTAAACTTGTGTCAAAATATGCACCGTCTGGTGACCAGCCCCAAGCCATTGA
AACCTTGGTTGATAACATCGAGGGGGGCGAAAAAGCCCAGATTCTCATGGGGGCGACTGGTACTGGTAAGACCTATACCA
TGAGCCAGGTTATCGCCCGTGTCAATAAGCCAACCTTGGTCATCGCCCACAACAAGACCTTGGCTGGTCAGCTTTATAGT
GAGTTCAAGGAATTCTTTCCAGAAAATGCGGTCGAATACTTCGTGTCTTACTATGATTACTACCAGCCAGAAGCTTATGT
ACCGTCTAGCGATACCTATATCGAAAAGGATAGTTCGGTCAATGATGAGATTGACAAACTCCGTCACTCTGCGACCTCAG
CTCTGCTAGAACGCAATGATGTCATTGTGGTAGCTTCTGTTTCTTGTATCTACGGTTTGGGTTCACCCAAGGAATATTCA
GATAGCGTGGTCAGCCTGCGACCAGGTCAGGAGATTTCCCGTGATCAGTTGCTCAATGCCTTGGTGGATATCCAGTTTGA
GCGGAACGACATCGACTTCCAACGGGGACGGTTCCGTGTGCGTGGCGATGTGGTGGAGATTTTCCCAGCTTCCCGTGACG
AACATGCCTTTCGTGTGGAGTTTTTCGGGGATGAAATCGACCGCATTCGTGAGATTGAAAGCCTGACAGGCAAGGTTTTG
GGCGATGTGGACCACTTGGCCATTTTCCCTGCCACCCACTTCGTGACCAACGATGACCACATGGAAACGGCCATTGCCAA
GATTCAGGCGGAACTAGAAGAGCAACTCAAGGTCTTTGAGGCAGAAGGAAAACTCTTAGAAGCTCAGCGATTGAAACAAC
GAACCGACTACGATATCGAGATGCTTCGGGAGATGGGCTATACCAACGGAGTTGAGAACTATTCACGACACATGGACGGG
CGAAGTGAGGGGGAGCCTCCTTATACCCTGCTGGACTTTTTCCCTGAGGACTATCTGATTATGATTGACGAGAGCCACAT
GACCATGGGGCAGATTAAGGGGATGTACAATGGTGACCGCTCACGCAAGGAGATGCTGGTTAACTATGGTTTCCGTCTAC
CGAGTGCATTGGATAATCGTCCGCTGCGCAGGGAAGAATTTGAGAGTCATGTCCACCAGATTGTCTATGTATCTGCGACG
CCGGGTGACTATGAAATGGAGCAGACAGAGACCGTTGTCGAGCAGATTATCCGGCCGACCGGGCTTTTGGATCCAGAAGT
GGAAGTCCGTCCAACTATGGGCCAAATGGACGACCTCCTAGGTGAAATCAATGCCCGTGTTGAAAAAGGCGAGCGAACCT
TTATCACTACCCTGACCAAGAAAATGGCAGAGGACTTGACCGACTACCTGAAAGAAATGGGCGTCAAGGTCAAGTATATG
CACTCGGACATCAAGACCTTGGAGCGTACGGAGATTATCCGTGATCTTCGCTTGGGTGTCTTTGATGTTTTGATAGGGAT
TAACCTGCTTCGTGAAGGGATTGACGTGCCAGAAGTTAGTCTAGTCGCTATCTTAGACGCAGACAAGGAGGGCTTCCTCC
GTAATGAACGGGGGCTCATCCAGACAATCGGTCGAGCGGCTCGTAACTCTGAAGGTCATGTGATTATGTATGCGGACAAG
GTCACCGAGTCCATGCGGAAGGCCATGGAAGAAACAGCCCGCCGCCGTCAAATCCAGATGGCTTATAATGAAGAGCATGG
CATTATTCCACAGACCATTAAGAAAGAGATCCGTGACCTGATTAGCGTGACCAAGGCTGTCACTCAGGACAAGGAAGAGG
TTGTGGACTTCAATGCTCTTAATAAAGATGAACGCAAGGCCATGATCAAGAAACTGGAAGGTCAGATGCAGGAAGCCGCA
GAAGTGCTTGACTTTGAACTGGCAGCCCAGATTCGCGATATGGTCATTGAGTTGAAGAATATGTAG

Domains

Predicted by InterProScan.

• Ultra-violet resistance protein B (UvrB) (556-598)

• Type III restriction enzyme, res subunit (ResIII) (21-143)

• UvrB/uvrC motif (UVR) (626-660)

• UvrB interaction domain (UvrB_inter) (164-254)

• Helicase conserved C-terminal domain (Helicase_C) (445-549)

3D structure

• AlphaFold DB: A0A0H3N3Z6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrB	Streptococcus pneumoniae R6	91.225	100	0.912
uvrB	Streptococcus pneumoniae D39	91.225	100	0.912
uvrB	Streptococcus pneumoniae TIGR4	91.074	100	0.911