Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   H7679_RS02460 Genome accession   NZ_AP023392
Coordinates   471858..473150 (+) Length   430 a.a.
NCBI ID   WP_184496055.1    Uniprot ID   -
Organism   Streptococcus suis strain DAT300     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 466858..478150
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7679_RS02435 (DAT300_04490) - 467663..468304 (+) 642 WP_024413700.1 response regulator transcription factor -
  H7679_RS02440 (DAT300_04500) - 468354..469754 (+) 1401 WP_024413701.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  H7679_RS02445 (DAT300_04510) - 469756..470127 (+) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -
  H7679_RS02450 (DAT300_04520) cysK 470153..471079 (-) 927 WP_024413702.1 cysteine synthase A -
  H7679_RS02455 (DAT300_04530) - 471169..471801 (-) 633 WP_024389592.1 YigZ family protein -
  H7679_RS02460 (DAT300_04540) comFA/cflA 471858..473150 (+) 1293 WP_184496055.1 DEAD/DEAH box helicase Machinery gene
  H7679_RS02465 (DAT300_04550) - 473143..473808 (+) 666 WP_024389594.1 ComF family protein -
  H7679_RS02470 (DAT300_04560) hpf 473885..474427 (+) 543 WP_004194117.1 ribosome hibernation-promoting factor, HPF/YfiA family -

Sequence

Protein


Download         Length: 430 a.a.        Molecular weight: 48880.50 Da        Isoelectric Point: 9.2911

>NTDB_id=82940 H7679_RS02460 WP_184496055.1 471858..473150(+) (comFA/cflA) [Streptococcus suis strain DAT300]
MKELENYYGRLFTKYQLTAKEREIAEKVPSITKKNNCFRCGTTFKEENKLPNDAYYCRACLLLGRVRSDEKLYHFPQKDF
PITKCLKWKGQLTDWQQRISDGLVANVENNRATLVHAVTGAGKTEMIYHTVASVIDKGGAVCLASPRIDVCIELYKRLQN
DFSVPISLLHGESEPYFRTPLVVATTHQLLKFYQAFDLVLIDEVDAFPYADNPMLYQAVDNAVKEAGVQVFLTATSTDEL
DKKVRTGKLSRLSLPRRFHGNPLVVPQKVWFSKFDDTLKKNRLVPKLKKAIEEQRKSGFPLLIFVPEISKGQEFTKIMKK
TFPEETIGFVSSQTENRLEIVEGFRKREITVLISTTILERGVTFPCVDVFVVQANHYLFTASSLVQIAGRVGRSIERPTG
LLQFYHEGSTGAIEKAIAEIKQMNKEAGYV

Nucleotide


Download         Length: 1293 bp        

>NTDB_id=82940 H7679_RS02460 WP_184496055.1 471858..473150(+) (comFA/cflA) [Streptococcus suis strain DAT300]
ATGAAAGAATTAGAAAATTATTATGGAAGATTATTTACCAAATACCAATTGACAGCAAAAGAAAGAGAAATAGCAGAAAA
AGTGCCAAGTATTACAAAAAAGAATAACTGCTTTCGCTGTGGAACAACTTTTAAAGAAGAAAACAAATTGCCAAACGATG
CTTATTACTGTAGAGCCTGCTTGCTTCTAGGCAGAGTGCGGTCAGACGAAAAACTCTATCATTTTCCTCAGAAAGATTTT
CCAATTACTAAGTGTTTAAAGTGGAAAGGTCAACTAACTGATTGGCAACAAAGAATTTCAGATGGACTAGTTGCAAACGT
GGAAAATAATCGTGCGACATTGGTTCATGCAGTAACAGGAGCAGGTAAGACAGAAATGATCTACCATACCGTTGCCTCAG
TGATTGATAAAGGCGGAGCGGTTTGCCTAGCCAGTCCTCGAATTGATGTTTGTATCGAACTCTATAAACGTCTGCAAAAT
GACTTTTCAGTTCCAATTAGTTTACTACATGGAGAGTCTGAACCCTATTTCCGAACCCCATTAGTTGTAGCAACCACACA
TCAGTTATTAAAATTTTATCAGGCCTTTGATTTGGTTTTGATTGATGAAGTAGACGCCTTTCCCTATGCAGATAATCCCA
TGCTCTATCAAGCAGTAGACAATGCGGTCAAGGAAGCCGGTGTTCAAGTTTTTCTGACGGCGACTTCAACAGATGAATTG
GATAAAAAAGTCAGAACAGGCAAATTAAGCCGTCTTAGTTTGCCAAGGCGCTTTCATGGCAACCCACTTGTTGTCCCGCA
AAAAGTCTGGTTTAGTAAATTCGATGATACCCTAAAGAAAAATAGACTAGTTCCAAAGTTGAAAAAAGCGATTGAAGAAC
AGAGAAAGTCGGGCTTCCCCTTACTCATTTTTGTCCCAGAAATCTCTAAAGGTCAAGAATTTACCAAGATAATGAAAAAA
ACATTCCCAGAAGAAACAATTGGCTTTGTATCCAGTCAAACAGAAAATCGCCTTGAAATAGTTGAAGGGTTTCGCAAGAG
AGAAATCACAGTCTTAATCTCGACTACTATTCTTGAACGTGGGGTGACCTTCCCATGTGTAGACGTCTTTGTTGTTCAAG
CCAATCATTACCTCTTCACAGCGTCAAGTCTTGTTCAGATTGCAGGCCGGGTCGGCAGGAGTATAGAACGTCCGACTGGT
TTACTCCAGTTTTATCATGAGGGAAGTACAGGAGCCATTGAAAAGGCAATCGCTGAAATTAAACAGATGAACAAGGAGGC
TGGTTATGTCTAA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(289-393)

Type III restriction enzyme, res subunit (ResIII)

(91-235)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

67.517

100

0.677
  comFA/cflA Streptococcus pneumoniae Rx1

66.821

100

0.67
  comFA/cflA Streptococcus pneumoniae D39

66.821

100

0.67
  comFA/cflA Streptococcus pneumoniae R6

66.821

100

0.67
  comFA/cflA Streptococcus pneumoniae TIGR4

66.821

100

0.67
  comFA/cflA Streptococcus mitis SK321

66.357

100

0.665
  comFA Lactococcus lactis subsp. cremoris KW2

54.408

92.326

0.502
  comFA Latilactobacillus sakei subsp. sakei 23K

38.515

100

0.386
  comFA Bacillus subtilis subsp. subtilis str. 168

38.072

96.512

0.367

Multiple sequence alignment