Detailed information NTG0082801

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: H7675_RS06925
• Genome accession: NZ_AP023389
• Coordinates: 1389625..1390626 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain KUN-0012590
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1384625..1395626

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7675_RS06910 (KUN2590_13140)	thrS	1384795..1386738 (-)	1944	WP_184004612.1	threonine--tRNA ligase	-
H7675_RS06915 (KUN2590_13150)	-	1387160..1388494 (-)	1335	WP_011284590.1	glycosyltransferase family 4 protein	-
H7675_RS06920 (KUN2590_13160)	-	1388496..1389494 (-)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
H7675_RS06925 (KUN2590_13170)	ccpA	1389625..1390626 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
H7675_RS06930 (KUN2590_13180)	-	1390800..1391885 (+)	1086	WP_031488434.1	aminopeptidase P family protein	-
H7675_RS06935 (KUN2590_13190)	-	1391934..1392599 (+)	666	WP_031488435.1	NAD(P)H-dependent oxidoreductase	-
H7675_RS06940 (KUN2590_13200)	-	1392610..1392987 (+)	378	WP_002985686.1	VOC family protein	-
H7675_RS06945 (KUN2590_13210)	-	1393132..1394058 (+)	927	WP_002994177.1	glycosyltransferase family 2 protein	-
H7675_RS06950 (KUN2590_13220)	-	1394269..1394952 (+)	684	WP_002990714.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=82801 H7675_RS06925 WP_002985680.1 1389625..1390626(-) (ccpA) [Streptococcus pyogenes strain KUN-0012590]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=82801 H7675_RS06925 WP_002985680.1 1389625..1390626(-) (ccpA) [Streptococcus pyogenes strain KUN-0012590]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACTAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559