Detailed information NTG0827461

Bioinformatically predicted

Overview

• Name: uvrB
• Type: Machinery gene
• Locus tag: SGW60_RS06110
• Genome accession: NZ_CP138667
• Coordinates: 1216198..1218183 (-)
• Length: 661 a.a.
• NCBI ID: WP_000229253.1
• Uniprot ID: A0A0H2XGZ8
• Organism: Staphylococcus aureus strain DA70900
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1211198..1223183

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SGW60_RS06100	hprK	1211860..1212792 (-)	933	WP_000958224.1	HPr(Ser) kinase/phosphatase	-
SGW60_RS06105	uvrA	1213344..1216190 (-)	2847	WP_000662681.1	excinuclease ABC subunit UvrA	Machinery gene
SGW60_RS06110	uvrB	1216198..1218183 (-)	1986	WP_000229253.1	excinuclease ABC subunit UvrB	Machinery gene
SGW60_RS06115	-	1218452..1218688 (-)	237	WP_000638419.1	CsbA family protein	-
SGW60_RS06120	-	1218685..1219335 (-)	651	WP_000538141.1	YfbR-like 5'-deoxynucleotidase	-
SGW60_RS06125	-	1219509..1220348 (-)	840	WP_000753321.1	CHAP domain-containing protein	-
SGW60_RS06130	-	1220496..1220603 (-)	108	WP_072360986.1	hypothetical protein	-
SGW60_RS06140	-	1222173..1222277 (-)	105	WP_001790092.1	hypothetical protein	-

Sequence

Protein

• Length: 661 a.a.
• Molecular weight: 76648.34 Da
• Isoelectric Point: 5.0538

>NTDB_id=827461 SGW60_RS06110 WP_000229253.1 1216198..1218183(-) (uvrB) [Staphylococcus aureus strain DA70900]
MVEHYPFKIHSDFEPQGDQPQAIKEIVEGIKAGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFK
EFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLV
VSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEFFGDEIDRIREVNYLTGEVLKER
EHFAIFPASHFVTREEKLKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPL
GSTPYTLLDYFGDDWLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGP
YEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQTRVERNERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSE
IKTLERIEIIRDLRMGTYDVIVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDKGEVIMYADKMTD
SMKYAIDETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKERQKTIDNIEKEMKQAAK
DLDFEKATELRDMLFELKAEG

Nucleotide

• Length: 1986 bp

>NTDB_id=827461 SGW60_RS06110 WP_000229253.1 1216198..1218183(-) (uvrB) [Staphylococcus aureus strain DA70900]
ATGGTTGAACATTATCCTTTTAAAATACATTCTGATTTTGAGCCTCAAGGTGACCAACCGCAAGCAATTAAAGAAATCGT
GGAAGGTATTAAAGCGGGGAAAAGACATCAAACTTTATTAGGTGCTACTGGCACAGGGAAAACATTTACGATGAGTAATG
TTATTAAAGAAGTTGGGAAACCAACGTTAATTATCGCGCATAACAAAACATTAGCAGGACAATTATATAGTGAGTTTAAA
GAATTTTTTCCTGAAAACAGGGTGGAATACTTTGTAAGTTACTATGATTATTATCAACCAGAGGCATACGTACCGTCTAC
TGACACTTTTATTGAAAAAGATGCCTCAATCAATGATGAAATTGATCAACTACGACATTCTGCTACAAGTGCATTATTTG
AACGCGATGATGTAATTATTATTGCTAGTGTAAGTTGTATATATGGTTTAGGTAATCCTGAAGAATATAAAGATTTAGTA
GTAAGTGTTCGAGTTGGTATGGAAATGGATAGAAGTGAATTACTTAGAAAACTTGTAGATGTGCAATATACACGAAATGA
CATCGATTTCCAACGAGGAACGTTTCGAGTGCGTGGTGATGTAGTGGAAATATTCCCAGCCTCTAAAGAAGAACTTTGTA
TAAGGGTTGAGTTTTTCGGCGATGAGATTGACCGTATCCGAGAAGTTAACTACCTAACAGGTGAAGTGTTGAAAGAAAGA
GAACATTTTGCGATATTCCCAGCTTCTCACTTCGTAACACGTGAAGAAAAGTTGAAAGTTGCGATTGAACGTATTGAAAA
AGAATTGGAAGAACGATTGAAAGAATTACGAGATGAGAATAAATTACTAGAAGCGCAAAGGTTAGAACAGCGTACCAACT
ATGATTTAGAAATGATGCGAGAGATGGGATTCTGTTCAGGAATTGAAAACTATTCCGTACATTTAACTTTGCGACCACTG
GGTTCGACACCATATACTTTATTGGATTACTTTGGCGATGATTGGTTAGTAATGATTGATGAATCACATGTGACATTACC
GCAAGTTCGAGGCATGTATAACGGAGACAGAGCGCGTAAACAAGTTTTGGTGGATCATGGGTTTAGATTACCGAGTGCAT
TAGATAACCGTCCACTTAAATTTGAAGAATTTGAAGAAAAGACAAAACAACTTGTGTATGTATCTGCAACGCCTGGACCA
TACGAAATTGAACATACGGATAAGATGGTTGAACAAATTATTCGTCCTACTGGTTTACTGGATCCTAAGATTGAGGTTAG
ACCTACTGAAAATCAAATTGACGATTTATTAAGTGAAATTCAAACAAGAGTTGAGCGTAATGAACGCGTACTTGTTACAA
CGCTCACTAAAAAGATGAGTGAAGATTTAACCACATACATGAAAGAAGCGGGTATTAAAGTTAATTATCTGCATTCAGAA
ATCAAGACATTAGAACGAATCGAAATAATTAGAGACTTACGAATGGGTACATATGATGTTATCGTAGGTATTAATTTATT
AAGAGAGGGTATTGATATACCAGAAGTTTCTCTAGTTGTCATATTAGATGCAGATAAAGAAGGGTTTTTACGTTCTAACC
GCTCATTAATTCAAACAATAGGTAGAGCTGCGCGTAACGATAAAGGTGAAGTCATTATGTATGCCGATAAAATGACTGAT
TCGATGAAGTATGCAATTGATGAGACACAACGTCGTCGAGAAATACAGATGAAACATAATGAAAAACATGGTATTACACC
TAAAACAATTAATAAAAAAATACATGATTTAATTAGTGCTACTGTTGAAAATGACGAAAATAATGACAAAGCACAAACTG
TGATACCTAAGAAGATGACGAAAAAAGAACGTCAAAAGACAATCGACAATATAGAAAAAGAAATGAAACAAGCAGCGAAA
GATTTAGATTTCGAGAAAGCTACAGAATTAAGAGATATGTTATTTGAATTAAAAGCAGAAGGGTGA

Domains

Predicted by InterProScan.

• Helicase conserved C-terminal domain (Helicase_C) (434-546)

• Ultra-violet resistance protein B (UvrB) (553-594)

• Type III restriction enzyme, res subunit (ResIII) (14-140)

• UvrB/uvrC motif (UVR) (626-659)

• UvrB interaction domain (UvrB_inter) (161-251)

3D structure

• AlphaFold DB: A0A0H2XGZ8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrB	Streptococcus pneumoniae R6	67.534	98.79	0.667
uvrB	Streptococcus pneumoniae TIGR4	67.534	98.79	0.667
uvrB	Streptococcus pneumoniae D39	67.534	98.79	0.667