Detailed information    

insolico Bioinformatically predicted

Overview

Name   pptA   Type   Regulator
Locus tag   H7674_RS02150 Genome accession   NZ_AP023388
Coordinates   420090..420815 (+) Length   241 a.a.
NCBI ID   WP_002983379.1    Uniprot ID   A0A4U7HHL6
Organism   Streptococcus pyogenes strain NIH35     
Function   export ComS (predicted from homology)   
Competence regulation

Genomic Context

Location: 415090..425815
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7674_RS02120 (SPNIH35_03700) - 415269..416729 (+) 1461 WP_002988645.1 NCS2 family permease -
  H7674_RS02125 (SPNIH35_03710) tsaE 416883..417344 (+) 462 WP_002988647.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  H7674_RS02130 (SPNIH35_03720) - 417319..417843 (+) 525 WP_011285082.1 GNAT family N-acetyltransferase -
  H7674_RS02135 (SPNIH35_03730) brpA 417852..419135 (+) 1284 WP_002983372.1 biofilm formation/cell division transcriptional regulator BrpA -
  H7674_RS02140 (SPNIH35_03740) - 419246..419602 (-) 357 WP_002988657.1 hypothetical protein -
  H7674_RS02145 (SPNIH35_03750) - 419599..420018 (-) 420 WP_011285081.1 HIT family protein -
  H7674_RS02150 (SPNIH35_03760) pptA 420090..420815 (+) 726 WP_002983379.1 ABC transporter ATP-binding protein Regulator
  H7674_RS02155 (SPNIH35_03770) - 420818..421852 (+) 1035 WP_011285080.1 ABC transporter permease -
  H7674_RS02160 (SPNIH35_03780) ccrZ 421916..422707 (+) 792 WP_002983385.1 cell cycle regulator CcrZ -
  H7674_RS02165 (SPNIH35_03790) trmB 422707..423342 (+) 636 WP_002983387.1 tRNA (guanosine(46)-N7)-methyltransferase TrmB -
  H7674_RS02175 (SPNIH35_03800) rimP 423601..424137 (+) 537 WP_002988815.1 ribosome maturation factor RimP -
  H7674_RS02180 (SPNIH35_03810) nusA 424312..425469 (+) 1158 WP_002983485.1 transcription termination factor NusA -
  H7674_RS02185 (SPNIH35_03820) rnpM 425485..425781 (+) 297 WP_002983486.1 RNase P modulator RnpM -

Sequence

Protein


Download         Length: 241 a.a.        Molecular weight: 26678.75 Da        Isoelectric Point: 4.5624

>NTDB_id=82728 H7674_RS02150 WP_002983379.1 420090..420815(+) (pptA) [Streptococcus pyogenes strain NIH35]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide


Download         Length: 726 bp        

>NTDB_id=82728 H7674_RS02150 WP_002983379.1 420090..420815(+) (pptA) [Streptococcus pyogenes strain NIH35]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGATAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCCTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGCTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(17-160)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4U7HHL6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pptA Streptococcus salivarius strain HSISS4

72.803

99.17

0.722
  pptA Streptococcus thermophilus LMD-9

71.967

99.17

0.714

Multiple sequence alignment