Detailed information NTG0082694

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: KUN2590_RS07800
• Genome accession: NZ_AP023387
• Coordinates: 1501253..1502254 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain NIH34
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1496253..1507254

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KUN2590_RS07785 (SPNIH34_14950)	thrS	1496423..1498366 (-)	1944	WP_011054265.1	threonine--tRNA ligase	-
KUN2590_RS07790 (SPNIH34_14960)	-	1498788..1500122 (-)	1335	WP_002985676.1	glycosyltransferase family 4 protein	-
KUN2590_RS07795 (SPNIH34_14970)	-	1500124..1501122 (-)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
KUN2590_RS07800 (SPNIH34_14980)	ccpA	1501253..1502254 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
KUN2590_RS07805 (SPNIH34_14990)	-	1502428..1503513 (+)	1086	WP_011054264.1	aminopeptidase P family protein	-
KUN2590_RS07810 (SPNIH34_15000)	-	1503562..1504227 (+)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
KUN2590_RS07815 (SPNIH34_15010)	-	1504238..1504615 (+)	378	WP_002985686.1	VOC family protein	-
KUN2590_RS07820 (SPNIH34_15020)	-	1504760..1505686 (+)	927	WP_011106859.1	glycosyltransferase family 2 protein	-
KUN2590_RS07825 (SPNIH34_15030)	-	1505897..1506580 (+)	684	WP_011017476.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=82694 KUN2590_RS07800 WP_002985680.1 1501253..1502254(-) (ccpA) [Streptococcus pyogenes strain NIH34]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=82694 KUN2590_RS07800 WP_002985680.1 1501253..1502254(-) (ccpA) [Streptococcus pyogenes strain NIH34]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCACGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559