Detailed information NTG0082601

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: R8635_RS10050
• Genome accession: NZ_AP026924
• Coordinates: 1940503..1941402 (-)
• Length: 299 a.a.
• NCBI ID: WP_219565679.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900700063
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1935503..1946402

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8635_RS10030 (PC0062_19730)	-	1935748..1937094 (-)	1347	WP_268217916.1	IS1380-like element ISSpn5 family transposase	-
R8635_RS10035 (PC0062_19740)	-	1937260..1937568 (-)	309	WP_000333257.1	hypothetical protein	-
R8635_RS10040 (PC0062_19750)	-	1937561..1938202 (-)	642	WP_000565531.1	ABC transporter ATP-binding protein	-
R8635_RS10045 (PC0062_19760)	-	1938204..1940234 (-)	2031	WP_050076226.1	bacteriocin-associated integral membrane family protein	-
R8635_RS10050 (PC0062_19770)	comR	1940503..1941402 (-)	900	WP_219565679.1	XRE family transcriptional regulator	Regulator
R8635_RS10055 (PC0062_19780)	rnmV	1941474..1942034 (-)	561	WP_000660011.1	ribonuclease M5	-
R8635_RS10060 (PC0062_19790)	-	1942034..1942807 (-)	774	WP_000575636.1	TatD family hydrolase	-
R8635_RS10065 (PC0062_19800)	-	1943112..1944083 (-)	972	Protein_1977	DUF1542 domain-containing protein	-
R8635_RS10070 (PC0062_19810)	rpmH	1944289..1944423 (-)	135	WP_000831905.1	50S ribosomal protein L34	-
R8635_RS10075 (PC0062_19820)	-	1944568..1945782 (-)	1215	WP_000666469.1	pyridoxal phosphate-dependent aminotransferase	-
R8635_RS10080	-	1945938..1946232 (-)	295	Protein_1980	hypothetical protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35400.15 Da
• Isoelectric Point: 4.7720

>NTDB_id=82601 R8635_RS10050 WP_219565679.1 1940503..1941402(-) (comR) [Streptococcus pneumoniae strain PZ900700063]
MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPSLPKLDYIAHRLGVPVYSLMPDFSALPPAYLELKYQI
LREPIYGKEEEYDKKEACLEEIYKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEVYSTNDMLL
IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDY
QKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAQLIGDEFLVKKLTEEWQEDVKKYL

Nucleotide

• Length: 900 bp

>NTDB_id=82601 R8635_RS10050 WP_219565679.1 1940503..1941402(-) (comR) [Streptococcus pneumoniae strain PZ900700063]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAATTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGA
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGACTATATTGCTCACC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTCCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTATGATAAGAAAGAAGCGTGTTTGGAAGAGATTTATAAAACATACTT
TGATAATCTTCCTAAAGAAGAACAATTAGCATGTGAAGTATTGCAGGCGTGTTTGGATACTTCTAGAACTAGAAGGCCTG
AATATGCAGAGTTAATACTTGAGGAACATATGCCTCAGATCATAGAAAAAGAAGTTTATTCAACAAATGATATGTTGTTG
ATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAAAGCTAATGCTCTT
TCTTTTGGAACAGAAAAAGGTAACTAAATTAGAAAACTTCTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTGTC
TTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCGTGTTTACAAGAAATTATGGATAAAACTCAAGATTAT
CAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGAAGAAAGAGATTTTAGTTTAGCTGAATCATT
TTATCAGTCTTCTAAAACATTTGCGCAGCTAATTGGAGATGAATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGAGG
ATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (70-291)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	37.755	98.328	0.371
comR	Streptococcus suis P1/7	37.457	97.324	0.365
comR	Streptococcus suis 05ZYH33	37.457	97.324	0.365
comR	Streptococcus pyogenes MGAS8232	36.577	99.666	0.365