Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilE   Type   Machinery gene
Locus tag   SE146_RS11170 Genome accession   NZ_CP138339
Coordinates   2117305..2117745 (-) Length   146 a.a.
NCBI ID   WP_319078439.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain TH2288     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2112305..2122745
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SE146_RS11140 (SE146_11125) - 2113372..2113871 (-) 500 Protein_2148 pilin -
  SE146_RS11145 (SE146_11130) pilE 2114240..2114383 (-) 144 WP_003691943.1 hypothetical protein Machinery gene
  SE146_RS11150 (SE146_11135) - 2114848..2115168 (-) 321 Protein_2150 pilin -
  SE146_RS11155 (SE146_11140) - 2115134..2115586 (-) 453 Protein_2151 pilin -
  SE146_RS11160 (SE146_11145) lpxC 2115715..2116638 (-) 924 WP_003687007.1 UDP-3-O-acyl-N-acetylglucosamine deacetylase -
  SE146_RS11170 (SE146_11155) pilE 2117305..2117745 (-) 441 WP_319078439.1 pilin Machinery gene
  SE146_RS11175 (SE146_11160) - 2117841..2118280 (-) 440 Protein_2154 pilin -
  SE146_RS11180 (SE146_11165) - 2118806..2119534 (-) 729 WP_353114220.1 pilin -
  SE146_RS11185 (SE146_11170) - 2119560..2119775 (-) 216 Protein_2156 pilin -
  SE146_RS11190 (SE146_11175) - 2120105..2120296 (+) 192 WP_014580443.1 hypothetical protein -
  SE146_RS11195 (SE146_11180) - 2120360..2121049 (-) 690 WP_003696506.1 SprT family zinc-dependent metalloprotease -
  SE146_RS11200 (SE146_11185) - 2121046..2121789 (-) 744 WP_003687014.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  SE146_RS11205 (SE146_11190) gmhB 2121819..2122382 (-) 564 WP_003687015.1 D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase -

Sequence

Protein


Download         Length: 146 a.a.        Molecular weight: 15755.55 Da        Isoelectric Point: 7.1360

>NTDB_id=824826 SE146_RS11170 WP_319078439.1 2117305..2117745(-) (pilE) [Neisseria gonorrhoeae strain TH2288]
MPTRLDSRLRGNDEAILLAEGQKSAVTEYYLNHGTWPENNGDAGVASASKIIGKYVKQVEVKNGVVTAQMASTGVNKEIQ
DKKLSLWAKREDGSVKWFCGQPVTRTEANAKAGTDDVAKADTTGKDKEIDTKHLPSTCRDESSAGT

Nucleotide


Download         Length: 441 bp        

>NTDB_id=824826 SE146_RS11170 WP_319078439.1 2117305..2117745(-) (pilE) [Neisseria gonorrhoeae strain TH2288]
GTGCCGACAAGGCTGGATTCCCGCCTGCGCGGGAATGACGAAGCCATCCTTTTGGCCGAAGGTCAAAAATCAGCCGTTAC
CGAGTATTACCTGAATCACGGCACATGGCCGGAAAACAACGGTGATGCCGGCGTGGCATCCGCTTCAAAAATCATAGGCA
AATATGTTAAGCAAGTTGAAGTCAAAAACGGCGTCGTTACCGCCCAAATGGCTTCAACCGGCGTAAACAAAGAAATCCAA
GACAAAAAACTCTCCCTGTGGGCCAAGCGTGAAGACGGTTCGGTAAAATGGTTCTGCGGACAGCCGGTTACGCGCACCGA
AGCCAACGCCAAAGCCGGCACCGACGACGTCGCCAAAGCCGACACCACCGGCAAAGACAAAGAAATCGACACCAAGCACC
TGCCGTCAACCTGCCGCGATGAATCATCTGCCGGTACGTGA

Domains

Predicted by InterProScan.

Pilin (bacterial filament) (Pilin)

(14-139)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilE Neisseria gonorrhoeae strain FA1090

72.414

99.315

0.719
  pilE Neisseria gonorrhoeae MS11

68.493

100

0.685