Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   R7234_RS17590 Genome accession   NZ_CP137737
Coordinates   3444722..3446743 (-) Length   673 a.a.
NCBI ID   WP_000042514.1    Uniprot ID   -
Organism   Escherichia coli strain HNSQ2209     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 3439722..3451743
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R7234_RS17560 (R7234_17560) moaE 3440522..3440974 (-) 453 WP_000852290.1 molybdopterin synthase catalytic subunit MoaE -
  R7234_RS17565 (R7234_17565) moaD 3440976..3441221 (-) 246 WP_000598619.1 molybdopterin synthase sulfur carrier subunit -
  R7234_RS17570 (R7234_17570) moaC 3441214..3441699 (-) 486 WP_053270373.1 cyclic pyranopterin monophosphate synthase MoaC -
  R7234_RS17575 (R7234_17575) moaB 3441702..3442214 (-) 513 WP_000084639.1 molybdenum cofactor biosynthesis protein B -
  R7234_RS17580 (R7234_17580) moaA 3442236..3443225 (-) 990 WP_001295301.1 GTP 3',8-cyclase MoaA -
  R7234_RS17585 (R7234_17585) yvcK 3443622..3444530 (+) 909 WP_001752329.1 uridine diphosphate-N-acetylglucosamine-binding protein YvcK -
  R7234_RS17590 (R7234_17590) uvrB 3444722..3446743 (-) 2022 WP_000042514.1 excinuclease ABC subunit UvrB Machinery gene
  R7234_RS17595 (R7234_17595) bioD 3447322..3447999 (-) 678 WP_000044883.1 dethiobiotin synthase -
  R7234_RS17600 (R7234_17600) bioC 3447992..3448747 (-) 756 WP_063100612.1 malonyl-ACP O-methyltransferase BioC -
  R7234_RS17605 (R7234_17605) bioF 3448734..3449888 (-) 1155 WP_000118811.1 8-amino-7-oxononanoate synthase -
  R7234_RS17610 (R7234_17610) bioB 3449885..3450925 (-) 1041 WP_000951213.1 biotin synthase BioB -

Sequence

Protein


Download         Length: 673 a.a.        Molecular weight: 76254.11 Da        Isoelectric Point: 4.8843

>NTDB_id=823966 R7234_RS17590 WP_000042514.1 3444722..3446743(-) (uvrB) [Escherichia coli strain HNSQ2209]
MSKPFKLNSAFKPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSGKTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEF
FPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKAMLERRDVIVVASVSAIYGLGDPDLYLKMMLH
LTVGMIIDQRAILRRLAELQYARNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFDEEVERLSLFDPLTGQIVSTIPR
FTIYPKTHYVTPRERILQAMEEIKEELAARRKVLLENNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGE
PPPTLFDYLPADGLLVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYVSATPGNYE
LEKSGGDVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVLVTTLTKRMAEDLTEYLEEHGERVRYLHSDI
DTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPS
MAKAIGETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGRGKSRPIVEPDNVPMDMSPKALQQKIHELE
GLMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS

Nucleotide


Download         Length: 2022 bp        

>NTDB_id=823966 R7234_RS17590 WP_000042514.1 3444722..3446743(-) (uvrB) [Escherichia coli strain HNSQ2209]
ATGAGTAAACCGTTCAAACTGAATTCCGCTTTTAAACCTTCTGGCGATCAGCCAGAGGCGATTCGACGTCTCGAAGAGGG
GCTGGAAGATGGCCTGGCGCACCAGACGTTACTTGGCGTGACTGGCTCCGGGAAAACCTTCACCATTGCCAATGTCATTG
CTGACCTTCAGCGCCCAACCATGGTACTTGCGCCCAACAAAACGCTGGCGGCCCAGCTGTATGGCGAAATGAAAGAGTTC
TTCCCGGAAAACGCGGTGGAGTATTTCGTCTCCTACTACGACTACTATCAGCCGGAAGCCTATGTACCGAGTTCCGACAC
CTTCATTGAGAAAGATGCCTCGGTTAACGAACATATTGAGCAGATGCGTTTGTCCGCCACCAAAGCGATGCTGGAGCGGC
GTGATGTGATTGTAGTGGCCTCTGTTTCCGCGATTTATGGTCTGGGCGATCCTGATTTATATCTCAAGATGATGCTCCAT
CTCACGGTCGGTATGATTATCGATCAGCGCGCGATTCTGCGCCGACTGGCGGAGCTGCAATACGCTCGTAATGATCAAGC
ATTCCAGCGTGGTACTTTCCGTGTTCGTGGCGAGGTGATTGATATCTTCCCGGCAGAATCGGATGACATTGCACTTCGCG
TGGAACTGTTTGACGAGGAAGTGGAACGATTGTCGTTATTTGACCCGCTAACCGGGCAGATTGTTTCCACCATTCCACGT
TTTACCATCTACCCGAAAACGCACTACGTCACACCGCGCGAGCGCATCCTACAGGCGATGGAGGAGATCAAAGAAGAGCT
GGCCGCCAGACGCAAAGTGCTATTGGAAAACAACAAACTGCTGGAAGAGCAGCGGCTGACCCAGCGTACCCAGTTTGATC
TGGAGATGATGAACGAGCTGGGCTACTGTTCGGGGATTGAAAACTACTCGCGCTTCCTCTCCGGTCGTGGACCGGGTGAG
CCACCGCCGACGCTGTTTGATTACCTGCCTGCCGATGGGCTGCTGGTGGTCGATGAATCTCACGTCACCATTCCACAAAT
TGGCGGCATGTATCGCGGTGACCGGGCGCGTAAAGAGACACTGGTGGAGTACGGCTTCCGCCTGCCATCAGCGCTGGATA
ACCGTCCGCTTAAGTTTGAAGAGTTCGAAGCATTAGCGCCGCAAACCATCTATGTTTCGGCGACGCCGGGTAATTACGAG
CTGGAAAAATCCGGCGGCGATGTGGTGGATCAGGTGGTGCGTCCAACCGGATTGCTTGACCCGATTATCGAAGTGCGGCC
GGTGGCGACACAGGTTGATGATCTTCTTTCGGAGATTCGTCAGCGAGCGGCAATTAACGAACGCGTACTGGTCACCACAC
TGACCAAGCGGATGGCGGAAGATCTTACCGAATATCTCGAAGAACATGGCGAGCGCGTGCGTTATCTTCACTCAGATATC
GACACCGTCGAACGTATGGAGATTATCCGCGACTTGCGTCTGGGTGAGTTCGACGTGCTGGTAGGGATCAACTTACTGCG
CGAAGGTCTGGATATGCCGGAAGTGTCGCTGGTGGCGATCCTCGACGCTGACAAAGAAGGCTTCCTGCGTTCCGAACGTT
CGTTGATCCAGACTATTGGTCGTGCGGCACGTAACGTTAACGGTAAAGCGATTCTCTACGGCGATAAGATCACCCCATCA
ATGGCGAAAGCGATTGGCGAAACCGAACGTCGCCGCGAGAAACAGCAGAAGTACAACGAGGAACACGGCATTACGCCGCA
AGGCTTGAACAAGAAAGTGGTCGATATCCTGGCGCTGGGGCAGAACATCGCCAAAACCAAAGCGAAGGGCAGAGGAAAAT
CGCGCCCGATTGTTGAGCCGGATAATGTGCCGATGGATATGTCGCCGAAAGCGTTGCAGCAGAAAATCCATGAACTGGAA
GGGCTGATGATGCAACATGCGCAGAATCTGGAGTTCGAAGAAGCGGCGCAAATTCGTGACCAGTTGCATCAGCTGCGTGA
GCTGTTTATCGCGGCTTCGTGA

Domains

Predicted by InterProScan.

UvrB interaction domain (UvrB_inter)

(159-249)

UvrB/uvrC motif (UVR)

(634-667)

Type III restriction enzyme, res subunit (ResIII)

(13-92)

Helicase conserved C-terminal domain (Helicase_C)

(436-544)

Ultra-violet resistance protein B (UvrB)

(552-593)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae TIGR4

56.522

99.108

0.56
  uvrB Streptococcus pneumoniae R6

56.372

99.108

0.559
  uvrB Streptococcus pneumoniae D39

56.372

99.108

0.559